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      • Young Girl Bra’s Market Research and Product Development Based on Functionality Value Study

        Cai, Jian-mei;Wen, Yingyu;Gan, Wen-yun 한양대학교 2011 韓國 生活 科學 硏究 Vol.31 No.1

        The young girl bra market awaked, it created the industrial value would be unable to estimate. This study sets out to focus on the analysis of young girl bra’s market research and product development based on functionality value. The methodology for this research involves multiple case studies involving girl bra target consumers. Functionality value and related theory guide product development concept as the key point. The research has identified young girl bra market is a size able blank in China. How to guide consumers’consumption awareness correctly by developing the functionality girl bra would be this research’s achievement. The paper linked scientific theory with practical market demand closely, comprehensive analysis of characteristics of adolescent girls in perfect underwear market segment, correct guidance bra consumer market, meet the girl consumer demand, and on the basis of functionality value in girls bra development would better reflected. The observations and analyses of girl bra functionality value would be the core of this paper, which is rarely known by people.

      • Prevalence of Human Papillomavirus Infection in Oral Squamous Cell Carcinoma: a Case-control Study in Wuhan, China

        Gan, Li-Li,Zhang, Hao,Guo, Ji-Hua,Fan, Ming-Wen Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

        High risk forms of the human papilloma virus (HPV) are generally accepted as necessary causative agents for cervical cancer. Recently, a possible relation between HPV and oral squamous cell carcinoma (OSCC) has also been noticed. The present study was conducted to investigate the prevalence of HPV infection in OSCCs in Wuhan city. DNA samples were collected from fresh tissues in 200 patients with OSCC and 68 normal controls. The polymerase chain reaction and direct sequencing were used to identify the HPV types in the samples. The prevalence of HPV of all types in the OSCC group was higher than in the control group (55/200 vs 2/68, OR=11.5, 95% CI=2.6-50.2). HPV16 and HPV18 were the main types detected, with HPV6 was the only low-risk type identified. High-risk HPV types HPV16 and HPV18 are prevalent in OSCC patients and may participate in the development of OSCC with traditional risk factors, tobacco and alcohol, possibly exerting synergistic effects. The results of multinomial logistic regression showed that those who smoked, consumed alcohol and with HPV infection have the highest risk of developing oral cancer (OR=13.3, 95% CI=3.1-56.8). Adjusted for age, smoking and alcohol use, HPV infection was independently associated with oral squamous cell carcinoma.

      • Application of Improved Decision Tree Method based on Rough Set in Building Smart Medical Analysis CRM System

        Hongsheng Xu,Lan Wang,Wenli Gan 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.1

        Medical Customer Relationship Management (CRM) is a kind of study method for the patient and potential patient carries on the exchange, timely access to and convey information, tracking to give the necessary guidance. The purpose of community hospital CRM is the daily business management and decision analysis of the hospital with the relationship between doctors and patients. Decision tree learning is an inductive learning algorithm based example. Rough set theory is used to process uncertain and imprecise information. In this paper, a decision tree algorithm based on rough set is proposed, and the improved decision tree algorithm based on rough classification is better than the standard C4.5 algorithm in classification accuracy and regression rate by experiment. Finally, the improved decision tree method is applied to the smart medical analysis CRM system. The experimental results show that the method can improve the management efficiency of CRM.

      • KCI등재

        Antiserum Preparation of Recombinant Sweet Potato Latent Virus-Lotus (SPLV-Lotus) Coat Protein and Application for Virus-Infected Lotus Plant Detection

        Zhen He,Tingting Dong,Wen Chen,Tielin Wang,Haifeng Gan,LiangJun Li 한국식물병리학회 2020 Plant Pathology Journal Vol.36 No.6

        Lotus is one of the most important aquatic vegetables in China. Previously, we detected sweet potato latent virus from lotus (SPLV-lotus) and found that it has highly significant sequence diversity with SPLV-sweet potato isolates (SPLV-sp). Here, we developed serological methods for the detection of SPLV-lotus in Chinese lotus cultivation areas. Based on the high sensitivity of SPLV-lotus coat protein antiserum, rapid, sensitive and large-scale diagnosis methods of enzyme-linked immunosorbent assay (ELISA) and dot blot in lotus planting area were developed. The established ELISA and dot blot diagnostic methods can be used to detect SPLVlotus from samples successfully. And our results also showed that the SPLV-lotus and sweet potato isolates appeared clearly distinction in serology. Our study provides a high-throughput, sensitive, and rapid diagnostic method based on serology that can detect SPLV on lotus, which is suggested to be included in viral disease management approach due to its good detection level.

      • KCI등재

        Strength criterion of plain recycled aggregate concrete under biaxial compression

        Zhen-Jun He,Gan-Wen Liu,Wan-Lin Cao,Chang-Yang Zhou,Zhang Jia-Xing 사단법인 한국계산역학회 2015 Computers and Concrete, An International Journal Vol.16 No.2

        This paper presents results of biaxial compressive tests and strength criterion on two replacement percentages of recycled coarse aggregate (RPRCA) by mass for plain structural recycled aggregate concrete (RAC) at all kinds of stress ratios. The failure mode characteristic of specimens and the direction of the cracks were observed and described. The two principally static strengths in the corresponding stress state were measured. The influence of the stress ratios on the biaxial strengths of RAC was also analyzed. The experimental results showed that the ratios of the biaxial compressive strength  3f to the corresponding uniaxial compressive strength c for the two RAC are higher than that of the conventional concrete (CC), and dependent on the replacement percentages of recycled coarse aggregate, stress states and stress ratios; however, the differences of tensile-compressive ratios for the two RAC and CC are smaller. On this basis, a new failure criterion with the stress ratios is proposed for plain RAC under biaxial compressive stress states. It provides the experimental and theoretical foundations for strength analysis of RAC structures subject to complex loads.

      • Induction of Apoptosis in Glioma Cells and Upregulation of Fas Expression Using the Human Interferon-β Gene

        Guo, Yan,Wang, Gan,Gao, Wen-Wei,Cheng, Shi-Wen,Wang, Ren,Ju, Shi-Ming,Cao, He-Li,Tian, Heng-Li Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

        We investigated whether IFN-${\beta}$ inhibits the growth of human malignant glioma and induces glioma cell apoptosis using the human IFN-${\beta}$ gene transfected into glioma cells. A eukaryonic expression vector ($pSV2IFN{\beta}$) for IFN-${\beta}$ was transfected into the glioma cell line SHG44 using liposome transfection. Stable transfection and IFN-${\beta}$ expression were confirmed using an enzyme-linked immunosorbent assay (ELISA). Cell apoptosis was also assessed by Hoechst staining and electron microscopy. In vivo experiments were used to establish a SHG44 glioma model in nude mice. Liposomes containing the human IFN-${\beta}$ gene were injected into the SHG44 glioma of nude mice to observe glioma growth and calculate tumor size. Fas expression was evaluated using immunohistochemistry. The IFN-${\beta}$ gene was successfully transfected and expressed in the SHG44 glioma cells in vitro. A significant difference in the number of apoptotic cells was observed between transfected and non-transfected cells. Glioma growth in nude mice was inhibited in vivo, with significant induction of apoptosis. Fas expression was also elevated. The IFN-${\beta}$ gene induces apoptosis in glioma cells, possibly through upregulation of Fas. The IFN-${\beta}$ gene modulation in the Fas pathway and apoptosis in glioma cells may be important for the treatment of gliomas.

      • KCI등재

        Current updates and research on plant-based vaccines for coronavirus disease 2019

        Asqwin Uthaya Kumar,Kirthikah Kadiresen,Wen Cong Gan,Anna Pick Kiong Ling 대한백신학회 2021 Clinical and Experimental Vaccine Research Vol.10 No.1

        The primary outbreak of severe acute respiratory syndrome coronavirus 2, causing pneumonia-like symptoms in patients named coronavirus disease 2019 (COVID-19) had evolved into a global pandemic. COVID-19 has surpassed Middle East respiratory syndrome and severe acute respiratory syndrome in terms of rate and scale causing more than one million deaths. Development of an effective vaccine to fight against the spread of COVID-19 is the main goal of many countries around the world and plant-based vaccines are one of the available methods in vaccine developments. Plant-based vaccine has gained its reputation among researchers for its known effective manufacturing process and cost effectiveness. Many companies around the world are participating in the race to develop an effective vaccine by using the plant system. This review discusses different approaches used as well as highlights the challenges faced by various companies and research groups in developing the plant-based COVID-19 vaccine.

      • Semantic Annotation of Ontology by Using Rough Concept Lattice Isomorphic Model

        Hongsheng Xu,Ruiling Zhang,Chunjie Lin,Wenli Gan 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.2

        Semantic annotation is the process based on ontology annotation concept class, attribute and other metadata for cyber source and its various parts. Ontology mapping is to calculate the similarity between two ontology elements. Ontology merging is two or more source ontology merging into a goal Ontology. The basic principle of the concept lattice isomorphic generating is isomorphic to the background of the isomorphic concept lattice, and as concept lattice isomorphic background can generate the concept lattice. This paper analyzes the methods of ontology mapping and merging based on rough concept lattice isomorphic model and presents semantic annotation of ontology by using rough concept lattice isomorphic model. Experiments show that this method is better than the traditional method in semantic annotation accuracy and breadth.

      • KCI등재

        Post-fire Study on Mechanical Properties of Damaged Ultra-high Strength Concrete

        Xiao Lyu,Guang-Hao Jia,Gan-Ping Shu,Xin Zhang,Er-Feng Du,Wen-Ming Wang 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.6

        In order to study the eff ect of steel tube, pre-load and temperature on residual performance of heated ultra-high strength concrete (UHSC), an experimental program was carried out to investigate the physical and mechanical properties of UHSC post-fi re in room temperature. With total of 54 standard cylindrical concrete specimens subjected to various temperatures ranging from 62 °C to 496 °C, their residual compressive strength, elastic modulus, peak strain was measured after natural cooling down. By comparing the test results of standard cylindrical concrete specimens with the results of the bare specimens in and after fi re, it is known that the residual compressive strength of standard cylindrical concrete specimens decayed more serious after exposing to same temperature. Seen from the results, the temperature which the specimens suff ered was found to be responsibility to the reduction of the compressive strength, elastic modulus, peak strain. As the temperature up to 300 °C, the strength reduction coeffi cient of UHSC was 0.67 ~ 0.68 and the elastic modulus reduction coeffi cient of UHSC was 0.41 ~ 0.51 with peak strain coeffi cient ε cr ( T ) /ε 0 1.57 ~ 1.67. Finally, based on the analysis of test results, simple formulae were proposed to describe the eff ect of temperature on residual performance of heated UHSC which infi lled the steel tube.

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