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      • KCI등재

        Structure and thermoelectric behavior of polyaniline-based/ CNT-composite

        Abd-Elsalam Ayat,Badr Hussein O.,Abdel-Rehim Ahmed A.,El-Mahallawi Iman S. 한국물리학회 2022 Current Applied Physics Vol.36 No.-

        Thermoelectric materials have the capability of harvesting and converting the heat wasted into useful electrical current. Polymer thermoelectric composites have recently received attention and experienced a rapid development because of their low density, versatility, ease of synthesis and processing and low thermal conductivity. Herein, we report on synthesis and characterization of pristine polyaniline and polyaniline/carbon nanotubes network nanocomposite. In the preparation, aniline was polymerized via a facile chemical oxidative polymerization process, in which 30 wt% multiwall carbon nanotubes were in situ incorporated. Both pristine polyaniline and its composite were examined by XRD. For their thermoelectric performance, Seebeck coefficient and electrical conductivity were characterized using a home-built setup operated by keithley Multimeter (Model:2000). The fabricated composite exhibited superior increase in Seebeck coefficient and power factor to reach 141 μV/K and 0.004 μW/mK2, respectively at 95 ◦C. The corresponding I–V curves were further measured. The current was found to increase substantially to reach 2.2 mA at 1 V; almost one order of magnitude higher when compared to that of the pristine polyaniline sample.

      • KCI등재

        Prevalence of Eosinophilic Esophagitis in Adult Patients with Upper Gastrointestinal Symptoms in a Locality in Upper Egypt

        Magdy Fouad,Yasser Mahrous Fouad,Hamdy Ahmed Mokareb,Dalia Mohammed Abdel-Rehim 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.4

        Background/Aims: Eosinophilic esophagitis (EoE) is gaining importance in the diagnosis of upper gastrointestinal (UGI) symptoms. Diagnosis is based on the clinical presentation of esophageal dysfunction and pathological findings in the absence of other causes oftissue eosinophilia. Our study was designed to evaluate EoE prevalence in patients with UGI symptoms in our locality (El-Minia, Egypt). Methods: This single-center, cross-sectional study recruited all patients with UGI symptoms who agreed for endoscopic evaluation. Esophageal biopsy samples were obtained and histological evaluation for the presence of eosinophils was performed for every patient. EoE was defined when at least 15 eosinophils were present in a single high-power field, in the absence of other causes of esophagealeosinophilia. Results: Between 2013 and 2015, 218 of 476 adult patients with UGI symptoms underwent upper endoscopy after giving consent. Amongthe 218 patients, only 4 (1.87%) had the diagnosis of EoE based on the presence of eosinophils in esophageal biopsies and exclusion ofother causes of esophageal eosinophilia. Three patients with EoE presented mainly with dysphagia (75%) and/or other UGI symptoms,such as heartburn. Conclusions: We observed a low prevalence of EoE in our locality. The diagnosis of EoE should be considered in patients withdysphagia and/or heartburn.

      • SCOPUSKCI등재

        Post-pandemic influenza A (H1N1) virus detection by real-time PCR and virus isolation

        Zaki, Ali Mohamed,Taha, Shereen El-Sayed,Shady, Nancy Mohamed Abu,Abdel-Rehim, Asmaa Saber,Mohammed, Hedya Said The Microbiological Society of Korea 2019 미생물학회지 Vol.55 No.1

        Influenza A (H1N1) virus caused a worldwide pandemic in 2009-2010 and still remains in seasonal circulation. Continuous surveillance activities are encouraged in the post pandemic phase to watch over the trend of occurrence every year, this is better to be done by a rapid and sensitive method for its detection. This study was conducted to detect proportions of occurrence of influenza A virus (H1N1) in patients with influenza-like illness. Samples from 500 patients with influenza or influenza-like clinical presentation were tested by real-time reverse transcription polymerase chain reaction (RT-PCR) and virus tissue culture. Among the total 500 participants, 193 (38.6%) were females and 307 (61.4%) males. Seventy-one patients (14.2%) were positive for H1N1 virus infection with real-time RT-PCR while 52 (10.4%) were positive by tissue culture. Non-statistically significant relation was found between age and gender with the positivity of H1N1. Sensitivity and specificity of real-time RT-PCR was 98.08% and 95.54%, respectively, in comparison to virus isolation with accuracy 95.8%. This study showed that H1N1 virus was responsible for a good proportion of influenza during the post-pandemic period. Real-time RT-PCR provides rapidity and sensitivity for the detection of influenza A virus (H1N1) compared with virus isolation and thus it is recommended as a diagnostic tool.

      • KCI등재

        Synthesis, Pharmacological Activity Evaluation and Molecular Modeling of New Polynuclear Heterocyclic Compounds Containing Benzimidazole Derivatives

        Fatma A. Bassyouni,Tamer S. Saleh,Mahmoud M. ElHefnawi,Sherein I. Abd El-Moez,Waled M. El-Senousy,Mohamed E. Abdel-Rehim 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.12

        Novel heterocyclic compounds containing benzimidazole derivatives were synthesized from 2-(1Hbenzimidazol-2-yl) acetonitrile (1) and arylhydrazononitrile derivative 2 was obtained via coupling of 1 with 4-methyl phenyldiazonium salt, which was then reacted with hydroxylamine hydrochloride to give amidooxime derivative 3. This product was cyclized into the corresponding oxadiazole derivative 4 upon reflux in acetic anhydride. Compound 4 was refluxed in DMF in the presence of triethylamine to give the corresponding 5-(1H-benzimidazol-2-yl)-2-p-tolyl-2H-1,2,3-triazol-4-amine 6. Treatment of compound 6 with ethyl chloroformate afforded 2,6-dihydro-2-(4-methylphenyl)-1,2,3-triazolo[4'',5''-4',5']pyrimido[1,6-a]benzimidazole-5(4H)-one (8). 1,2-bis(2-cyanomethyl-1H-benzimidazol-1-yl)ethane-1,2-dione (10) was synthesized via the condensation reaction of 2-(1H-benzimidazol-2-yl) acetonitrile (1) and diethyloxalate. The reactivity of compound 10 towards some diamine reagents was studied. The in vitro antimicrobial activity of the synthesized compounds was investigated against several pathogenic bacterial strains such as Escherichia coli O157, Salmonella typhimurium, E. coli O119, S. paratyphi, Pseudomonas aeruginosa, Staphylococcus aureus, Listeria monocytogenes and Bacillus cereus. The results of MIC revealed that compounds 12a-c showed the most effective antimicrobial activity against tested strains. On the other hand, compounds 12a, b exhibited high activity against rotavirus Wa strain while compounds 12b, c exhibited high activity against adenovirus type 7. In silico target prediction, docking and validation of the compounds 12a-c were performed. The dialkylglycine decarboxylase bacterial enzyme was predicted as a potential bacterial target receptor using pharmacophorebased correspondence with previous leads; giving the highest normalized scores and a high correlation docking score with mean inhibition concentrations. A novel binding mechanism was predicted after docking using the MOE software and its validation.

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