개에서 직장탈의 수술적 치료 1례

박정희,김영실,신영지,박창식,전무형,김명철,정성목 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

A 3-year old, male Jindo dog was referred with history of tenesmus, dyschezia and recurrent rectal prolapse. On the physical examination, the rectum was prolapsed about 10 cm, congested and necrotized. Fecal incontinence and pain were observed. Complete blood count revealed a mild leukocytosis and there were no remarkable abnormalities in serum biochemistry profiles. It was diagnosed as a rectal prolapse. Rectal resection and anastomosis was performed for necrotic tissue removal. On postoperative fecal smear, protothecosis was observed. Amphotericin B was administered. There has been no evidence of recurrence of rectal prolapse for ten months.

개에서 직장탈의 수술적 치료 1례

박정희,김영실,신영지,박창식,전무형,김명철,정성목 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

A 3-year old, male Jindo dog was referred with history of tenesmus, dyschezia and recurrent rectal prolapse. On the physical examination, the rectum was prolapsed about 10 em, congested and necrotized. Fecal incontinence and pain were observed. Complete blood count revealed a mild leukocytosis and there were no remarkable abnormalities in serum biochemistry profiles. It was diagnosed as a rectal prolapse. Rectal resection and anastomosis was performed for necrotic tissue removal. On postoperative fecal smear, protothecosis was observed. Amphotericin B was administered. There has been no evidence of recurrence of rectal prolapse for ten months.

개에 있어서 심장사상충증을 동반한 창상성 횡격막 허니아의 수술적 치료 1례

조승혁,임영환,손정민,노경완,박창식,전무형,김명철,송근호,정성목 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

A 7-month old. castrated male Shih-tzu dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with history of depression. dyspnea. mild scale. tachypnea. exercise intolerance and severe leanness. On physical examination. cardiac arrhythmias was heard and heart worm ELISA test was positive. Microfilaria was found on the direct blood smear. Survey radiographs showed loss of diaphragmatic line and cardiac silhouette. displacement of lung fields and presence of gas filled intestines in the thoracic cavity. Rib fracture and pelvic fracture with callus formation were found incidentally. On the basis of physical examination and radiographic findings. it was diagnosed as traumatic diaphragmatic hernia and heart worm disease. Herniorrhaphy was performed. Postoperatively. it was treated for heart worm disease and scale. There is no evidence of recurrence of diaphragmatic hernia and heart worm disease over 1 year.

개에 있어서 심장사상충증을 동반한 창상성 횡격막 허니아의 수술적 치료 1례

조승혁,임영환,손정민,노경완,박창식,전무형,김명철,송근호,정성목 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

A 7-month old, castrated male Shih-tzu dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with history of depression, dyspnea, mild scale, tachypnea, exercise intolerance and severe leanness. On physical examination, cardiac arrhythmias was heard and heart worm ELISA test was positive. Microfilaria was found on the direct blood smear. Survey radiographs showed loss of diaphragmatic line and cardiac silhouette, displacement of lung fields and presence of gas filled intestines in the thoracic cavity. Rib fracture and pelvic fracture with callus formation were found incidentally. On the basis of physical examination and radiographic findings, it was diagnosed as traumatic diaphragmatic hernia and heart worm disease. Herniorrhaphy was performed. Postoperatively, it was treated for heart worm disease and scale. There is no evidence of recurrence of diaphragmatic hernia and heart worm disease over 1 year.

Clinical Antagonistic Effect of Atipamezole in Cats Anesthetized with Tiletamine-Zolazepam and Medetomidine

Hyung-Ung Kim,Chang-Sik Park,Moo-Hyung Jun,Seong-Mok Jeong,Myung-Cheol Kim 한국임상수의학회 2007 한국임상수의학회지 Vol.24 No.2

Clinical Antagonistic Effect of Atipamezole in Cats Anesthetized with Tiletamine-Zolazepam and Medetomidine

Kim, Hyung-Ung,Park, Chang-Sik,Jun, Moo-Hyung,Jeong, Seong-Mok,Kim, Myung-Cheol 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

연구의 목적은 고양이에서 zoletil^(?)과 medetomidine 약물 마취 시 atipamezole의 임상적 길항 효과를 보기 위함이다. 마취를 하고 다시 회복 되는 동안에 체온, 심박수, 호흡수를 측정하였다. 이 연구에서는 12 마리의 건강한 한국 잡종 고양이를 사용하였다. 각 6마리씩 무작위로 선별하여 대조군(zoletil^(?)과 medetomidine, ZM)과 실험군(zoletil^(?), medetomidine과 길항제인 atipamezole, ZMA) 두 군으로 나누었다. 모든 고양이들은 투여 전 15분, 주사후 5분, 25분, 105분에 평가하였으며, 길항제인 atipamezole은 마취 주사 후 20분에 근육 주사 하였다. 회복 시간, 심박수, 호흡수는 두 군간 유의성이 있는 결과를 보였고 체온은 유의성을 나타내지 않았다. 두 군 모두 zoletil^(?)과 medetomidine 마취 주사 후 4분 내에 횡와 되는 결과를 보였고 마취 시간도 3시간 가까이 지속해 고양이에 있어서 이들 약물이 좋은 마취 효과가 있음을 보여 주었다. 회복 시 마취 부작용은 거의 보이지 않았다. 고양이가 마취에서 회복되어 기립 자세를 하기까지 걸리는 시간이 ZM 군에서는 210.8±45.6 시간으로 나타났고, ZMA 군에서는 154.2±21.1 시간으로 나타났다. 길항제를 투여한 ZMA 군에서 회복시간이 거의 한 시간 가까이 단축되어 ZMA군이 ZM군보다 회복이 빠르다는 결과를 보였다. 본 연구에서 atipamezole은 medetomidine-tiletamine/zolazepam으로 병용 마취된 고양이에서 유용한 회복효과를 발휘하였다. The purpose of the study is to evaluate the clinical antagonistic effect of atipamezole(0.25 mg/kg,IM) in cats anesthetized with tiletamine-zolazepam (zoletil^(?), 10 mg/kg, IM) and medetomidine (0.05 mg/kg, IM). Twelve healthy 1 year old Korean mixed breed cats were used for this study. They were 4 males and 8 females. These cats were randomly assigned to two groups. One was control group (Zoletil^(?) + medetomidine, ZM), and the other was treatment group (Zoletil^(?)+medetomidine and antagonism by atiparnezole, ZMA). All cats were examined 15 minutes before,5, 25, 65 and 105 minutes after administration of tiletarnine-zolazepam and medetomidine. Atipamezole was injected intramuscularly 20 minutes after ZM administation. Recovery time, heart rate, respiratory rate, total plasma protein and blood glucose were significantly different between ZM group and ZMA group (P < 0.05). However, rectal temperature was not significantly different between ZM group and ZMA group. Two groups were able to induce sternal recumbency within 2 minutes and lateral recumbency within 4 minutes after the anesthetics injection. Mean sternal position time (mean ± SD) was 174.0± 44.6 and 116.2 ± 27.3 minutes, and mean standing position time was 210.8 ± 45.6 and 154.2 ± 21.1 minutes in ZM and ZMA group, respectively. In these two groups, adverse effects during recovery time from anesthesia were not seen. As a result, the ZMA group had a faster recovery than the ZM group. Thus it was concluded that atipamezole could exert a useful reversal effect in cats anesthetized with rnedetornidine-tiletamine/zolazepam combination.

Attenuation of Renal Ischemia-Reperfusion Injury by Antioxidant Vitamins in Pigs

Kim, Myung-jin,Lee, Soo-jin,Park, Chang-sik,Son, Hwa-young,Jun, Moo-hyung,Jeong, Seong-mok,Kim, Myung-cheol 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

돼지에서 신장의 허혈-재관류 손상의 감소에 대한 비타민 C와 E의 영향을 알아보기 위하여 본 연구를 실시 하였다. 돼지 10두를 2개의 군으로 구분하여,60분 동안 체온과 같은 허혈을 한쪽 신장에 유발하고 반대쪽 신장은 절제하였다. 처치군은 수술 2일전 비타민 C와 E를 이틀 동안 전처치하고, 그 뒤에 수술 중 비타민 C와 heparin이 첨가 된 생리식염수를 관주-흡인 하였다. 대조군은 heparin이 첨가된 생리식염수의 관주-흡인만을 하였다. Blood urea nitrogen, creatinine 및 antioxidant superoxide dismutase (SOD)를 측정하기 위하여 수술 전,수술 후 1,3,7,14일에 혈액 샘플을 채취하였다. 수술 후 14일에 안락사를 시키고,병리조직검사를 위하여 신장를 적출하였다. BUN은 대조군과 처치군 사이에 수술 후 1일,3일 또는 7일에 유의성이 있는 차이가 인정되었다. (p < 0.05). Creatinine은 대조군과 처치군 사이에 수술 후 3일에 유의성이 있는 차이가 인정되었다 (p < 0.05). 혈장에서의 항산화 효소의 활성은 대조군과 처치군 사이에서 수술 후 14일에 유의성이 있는 차이가 인정되었다 (p < 0.05). 병리조직 검사 결과에서 처치군이 대조군 보다 더 적은 신장 세뇨관에서의 손상의 정도를 보였다. 비다민C와 E는 돼지에서 신장의 허혈-재관류 손상을 감소시켰다. This study was to investigate the effects of ascorbic acid and alpha-tocopherol on the attenuation of renal ischemia-reperfusion (IR) injury in pigs. Ten pigs were subjected to 60 minutes of warm unilateral renal ischemia followed by removal of contralateral kidney and then divided into two groups. Treatment group was performed ascorbic acid and alpha-tocopherol pretreatment 2 days before operation and ascorbic acid with heparin-saline solution irrigation-aspiration. Otherwise, control group used only irrigation-aspiration of heparin-saline solution. Blood samples were collected from these pigs for measurement of serum blood urea nitrogen (BUN) and creatinine values, antioxidant superoxide dismutase (SOD) at pre, day I, day 3, day 7 and day 14. The kidneys were taken for histopathologic evaluation after euthanasia on postoperative day 14. The levels of BUN were significantly increased in the control group on day 1, day 3 and day 7 (P < 0.05). And the level of creatinine was significantly increased in the control group on day 3 (p < 0.05). Activity of antioxidant enzymes in plasma revealed significant difference (p < 0.05) between control and treatment group at day 14. In histopathologic findings, treatment group was showed less damage than that of control group on the basis of renal tubular damage. It was concluded that ascorbic acid and alpha-tocopherol attenuated renal I/R injury in the pigs.

Attenuation of Renal Ischemia-Reperfusion Injury by AntioxidantVitamins in Pigs

Myung-jin Kim,Soo-jin Lee,Chang-sik Park,Hwa-young Son,Moo-hyung Jun,Seong-mok Jeong,Myung-cheol Kim 한국임상수의학회 2007 한국임상수의학회지 Vol.24 No.2

Acupuncture analgesia for operation in Korean native goats

Lee, Soo-jin,Park, Chang-sik,Jun, Moo-hyung,Kim, Nam-joong,Lee, Jae-il,Kim, Young-suk,Kim, Myung-jin,Lee, Jae-yon,Jeong, Seong-mok,Kim, Duck-hwan,Kim, Myung-cheol 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

The purpose of this study is to establish the analgesic effects of electroacupuncture for Korean native goat. Electroacupuncture was applied to the 6 Korean native goats. In 3 of them, rumenotomy was performed, and in the other 3, laparotomy was done. The analgesic induction time was 15 to 30 minutes. The acupoints used were Tian-ping (Celestial Peace, GV-5), Bai-hui (Hundred Meetings, Gv-20), left 13th thoracic nerve and left 3rd lumbar nerve. Electroacupuncture was performed in lateral recumbency. Needles were inserted 1-2cm deep, and connected to the electroacupuncture apparatus. The electrical stimulation condition was 30 Hz and 2-6 volts. Initially, the voltage of analgesia mode was maximized in each channel. And, the output was slowly reduced to the critical point that goats could tolerate without obvious discomfort or pain. Surgical operation was done successfully under electroacupuncture analgesia in 6 Korean native goats. In addition, the changes of temperature, heart rate and respiratory rate were studied during acupuncture analgesia. For 3 months after surgery, no experimental animals showed clinical problem in 6 Korean native goats.

Analgesic Effects of on the Oral Cavity by Electroacupuncture in Dogs

Choi, Kyeong-ha,Kim, Duck-hwan,Jeong, Seong-mok,Park, Chang-sik,Jun, Moo-hyung,Kim, Myung-cheol 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10