데스메막박리 자동각막내피층판이식술 후 발생한 단순포진바이러스 각막염 1예

정세형,조재갑,윤경철,Se Hyeong Jeong,MD,Jae Kap Cho,MD,Kyung Chul Yoon,MD 대한안과학회 2012 대한안과학회지 Vol.53 No.3

Purpose: To report a case of herpes simplex keratitis after descemet stripping automated endothelial keratoplasty (DSAEK). Case summary: A 66-year-old male underwent DSAEK in his right eye due to bullous keratopathy after cataract surgery. The corneal epithelium which was removed during surgery was healed, but the patient was experiencing pain and decreased visual acuity in his right eye 1 month after surgery. Increasing corneal epithelial defects and corneal edema were observed on slit-lamp examination. Therapeutic soft contact lenses and artificial tears were used for treatment but were not effective, thus amniotic membrane transplantation was performed. Three months after transplantation, the epithelial defect appeared as a geographic ulcer suspecting to be herpes simplex keratitis; therefore, ganciclovir ophthalmic ointment and oral acyclovir were administered. Six months after antiviral therapy, the epithelial lesion of herpes simplex keratitis completely disappeared, leaving only mild corneal opacity. Conclusions: If corneal epithelial defects are persistent after DSAEK in patients even with no past history of herpes simplex keratitis, herpes simplex keratitis should be considered in the differential diagnosis. J Korean Ophthalmol Soc 2012;53(3):473-477

전층각막이식술 후 각막감각의 장기 변화 및 이와 관련된 눈물막변수의 분석

정세형,오한진,윤경철,Se Hyeong Jeong,MD,Han Jin Oh,MD,Kyung Chul Yoon,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.9

Purpose: To evaluate the long-term changes in the corneal sensitivity and to analyze which tear film parameters correlate with corneal sensitivity after penetrating keratoplasty (PKP). Methods: Twenty-eight eyes of 28 patients who underwent PKP were included in the present study. Corneal sensitivity, Schirmer test, tear break-up time, tear clearance rate, and keratoepitheliopathy were evaluated at 1, 3, 6, 12, and 24 months postoperatively. Then, which tear film parameters correlated with corneal sensitivity during the follow-up period were analyzed. Results: Corneal sensitivity was 5.18 ± 3.96 mm at one month postoperatively and increased to 29.64 ± 12.39 mm (p < 0.05) at 24 months postoperatively but was still not in the normal range. Tear break-up time and keratoepitheliopathy improved at postoperative three months and six months, respectively, compared with one month postoperatively, and both measures normalized at 24 months postoperatively. Schirmer test results and tear clearance rate were in the normal range during the follow-up period. Corneal sensitivity was correlated with tear break-up time from three to 24 months postoperative and with tear clearance rate from one month to 24 months postoperative (p < 0.05). Conclusions: Change in corneal sensitivity after penetrating keratoplasty correlates with tear break-up time and tear clearance rate; therefore, tear break-up time and tear clearance rate can be used as parameters for management of dry eye after PKP. J Korean Ophthalmol Soc 2012;53(9):1247-1253

기존 치료에 반응하지 않는 진균 각막염에서 전방내 보리코나졸 주입술의 임상 효과

정세형,이효석,조재갑,윤경철,Se Hyeong Jeong,MD,Hyo Seok Lee,MD,Jae Kap Cho,MD,Kyung Chul Yoon,MD,PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.5

Purpose: To evaluate clinical effects of intracameral voriconazole injection in fungal keratitis refractory to conventional therapy. Methods: Thirty-eight eyes of 38 patients with fungal keratitis were included in this study. The patients were divided into 3 groups: 13 patients with intracameral voriconazole injection (50 μg/0.1 ml; group A), 11 patients with intracameral amphotericin B injection (10 μg/0.1 ml; group B), and 14 patients with conventional therapy only (group C). Clinical factors including treatment success rate and time to successful treatment were evaluated. Results: Treatment success was accomplished in 12 eyes in group A (92.3%), 10 eyes in group B (90.9%), and 12 eyes in group C (85.7%). Time to treatment success in group A, B, and C was 36.1 ± 10.4 days (p = 0.04), 34.2 ± 7.8 days (p = 0.03), and 49.5 ± 16.7 days, respectively. Patients who had received intracameral voriconazole injection or amphotericin B showed faster fungal keratitis improvement than patients who received conventional treatment. Time to re-epithelialization and time to disappearance of hypopyon showed a similar clinical course. Conclusions: Intracameral voriconazole injection, which has a similar therapeutic effect as intracameral amphotericin B injection in the management of fungal keratitis, can be helpful in the treatment of intractable fungal keratitis.

불확실 변동특성이 고려된 철골 평면 트러스의 이산화 최적설계

정세형(Jeong Se-Hyung),손수덕(Shon Su-Deok),오영대(Oh Young-Dae),강문명(Kang Moon-Myung) 대한건축학회 2003 大韓建築學會論文集 : 構造系 Vol.19 No.8

This study is proposed to suggest reliability analysis and stochastical discrete optimum design method using stochastic finite element method(SFEM) for plane steel trusses. Usually there are a lot of uncertainties about the error of assumed load, material property, member size and structural analysis in structures. In existing deterministic method, the member design has been accomplished applying safety factor after structural analysis, but it is not enough to consider the uncertainties of structure above mentioned. Thus, in order to consider uncertainties of structure, it is proposed the stochastical analysis method of plane steel trusses using the reliability analysis method, SFEM and advanced first order second moment method(AFSOM). And the optimum method applied in this study is micro-genetic algorithms with stochastical discrete optimum design method in satisfaction of target reliability index.

유수정체 안내후방렌즈삽입술 후 망막신경섬유층 두께 측정값의 변화

이태희,박정원,정세형,박상우,Tae Hee Lee,Jung Won Park,Se Hyung Jeong,Sang Woo Park 대한안과학회 2014 대한안과학회지 Vol.55 No.5

Purpose: In the present study we evaluated the changes of measured retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) after phakic intraocular lens (implantable collamer lens, ICL) implantation and analyzed the factors correlated with the changes of measured RNFL thickness. Methods: Forty eyes of 40 patients (Group A: 20 patients using spectral domain OCT and Group B: 20 patients using time domain OCT) who underwent ICL implantation were included in this study. RNFL thickness was measured 1 week before surgery and 1 month postoperatively using OCT. The changes of measured RNFL thickness and the correlation between patients' data were analyzed. Results: The postoperative measured RNFL thickness of the average, inferior, temporal, and superior quadrants were increased compared to preoperative measured RNFL thickness in Group A. Group B had similar results in the average, inferior, and superior quadrants (<em>p</em> < 0.05). However, the postoperative changes of RNFL measurements were not correlated with the preoperative spherical equivalent, the degree of spherical equivalent change and diopters of implanted lens (<em>p</em> > 0.05). Conclusions: The measured RNFL thickness after ICL implantation may increase compared to the preoperative value. Caution should be taken when interpreting the RNFL thickness values measured by OCT in patients with myopia who undergo ICL implantation. J Korean Ophthalmol Soc 2014;55(5):702-710

버섯부산물유래 가수분해효소분비 박테리아의 분리 및 동정

김영일 ( Young Il Kim ),정세형 ( Se Hyung Jeong ),석준상 ( Joon Sang Seok ),양시용 ( Si Yong Yang ),허정원 ( Jung Won Huh ),곽완섭 ( Wan Sup Kwak ) 한국동물자원과학회 2008 한국축산학회지 Vol.50 No.5

식품 및 환경, 기타 버섯폐배지로부터 섬유소분해력이 높은 중온성 균의 분리 및 균주생산을 위한 배지조건의 최적화

김영일 ( Young Il Kim ),정세형 ( Se Hyung Jung ),석준상 ( Joon San Seok ),양시용 ( Si Yong Yang ),허정원 ( Jeong Weon Huh ),곽완섭 ( Wan Sup Kwak ) 한국미생물생명공학회 2007 한국미생물·생명공학회지 Vol.35 No.3

가정용 ESS를 위한 10kW급 고효율 PCS 개발

박성열(Sung-Youl Park),정현주(Hyeon-Ju Jeong),권민호(Min-Ho Kwon),정세형(Se-Hyung Jung),최세완(Se-Wan Choi),송옹규(Yong-Gyu Song) 전력전자학회 2015 전력전자학술대회 논문집 Vol.2015 No.07

진화론적 구조최적화(ESO) 기법에 의한 위상최적화 연구

편해완(Pyeon Hae-Wan),大森博司(Ohmori Hiroshi),정세형(Jeong Se-Hyoung),강문명(Kang Moon-Myung) 대한건축학회 2003 大韓建築學會論文集 : 構造系 Vol.19 No.8

The purpose of this study is to improve convergence speed of topology optimization procedure for the plane and space structures using the existing ESO method. At the existing ESO topology optimization procedure for the plane and space structures, the adjustment of member sizes according to target stress has been executed by increasing or reducing a very small value from each member size. In this case, it takes too much iteration till convergence. Accordingly, it is practically hard to abtain optimum topology for a large scale structures. For that reason, it is necessary to improve convergence speed of ESO method more effectively. During the topology decision procedure, member sizes are adjusted by calculating approximate solution for member sizes corresponding to the target stress at every step, the new member sizes are adjusted by such method are applied in FEA procedure of next step. The member size adujusting methods for frame and truss structures are suggested in this study are Newton-Raphson method and direct stress corresponding method respectively.

지속가능한 남북교류 및 협력방안 고찰

강신형(Kang, Shin-Hyoung),신동수(Shin, Dong-Soo),정세형(Jeong, Se-Hyeong),최진호(Choi, Jin-Ho) 경희대학교 경희법학연구소 2013 KHU 글로벌 기업법무 리뷰 Vol.6 No.1

남북 간 교류 및 협력에 관하여 많은 연구와 논의들이 진행되고 있지만, 이러한 노력들은 현 재의 남북한이 처한 현실처럼 분쟁발생시 교류중단이라는 극한 상황에 치닫게 되면 한 순간 에 물거품이 되어 버릴지 모르는 치명적인 약점을 가지고 있다. 본고는 이러한 점에 착안하여 남북교류협력의 지속성에 논점을 맞추어 남북교류협력 방안에 대하여 고찰한다. 교류와 협력은 그 구체적 당사자 간의 신뢰 형성을 기반으로 하여야 하며 이를 구축하기 위해서 적지 않은 시간과 노력이 필요함은 당연하다. 그러나 오랜 신뢰형성과정 에도 불구하고 분쟁 발생시 조화로운 해결방안을 찾지 못하여 교류중단이라는 극단의 카드를 꺼내게 된다면 그 기반이 무너지는 것은 한 순간이며 그 결과 막대한 경제적 손해가 발생할 뿐 만 아니라 추후 교류 재개 시 그만큼의 또 다른 노력을 시작해야 하는 비효율성을 가져온다. 우선 이러한 문제점에 대한 해결방안을 검토하기 전에 기본적으로 선제되어야 할 분쟁 발생 전 남북교류협력 방안에 대하여 검토한다. 그 자체로서 지속가능성이 있는 교류협력방안이 전제되어 있어야 외적 요인으로 인한 지속성 차단 문제를 해결하기 위한 노력을 검토할 수 있기 때문이다. 이러한 논리를 바탕으로 정부차원, 민간차원 그리고 경제적, 인도적 차원으로 나누어 현재 남북교류협력의 현황을 알아보고 그 활성화 방안을 논의한다. 그 다음으로 이러한 논의를 통하여 검토된 구체적 방안들의 실효성을 지속적으로 유지시켜 나가기 위하여 그리고 이러한 노력의 궁극적 지향점인 통일을 목표로 한 남북의 지속가능한 교류협력을 이뤄내기 위하여, 교류협력 중단이라는 극단적 상황을 초래할 수 있는 분쟁을 해결하기 위한 방안을 실현가능성에 무게중심을 두고 모색한다. 이를 위해, 정부 간 분쟁해결 방안에 관해서는 ‘국제 중재’라는 국제분쟁해결 절차 적용에 관하여 논의한다. 그리고 민간 교류당사자의 분쟁에 관하여는 현재 남북상사분쟁해결절차합의 서를 기본 토대로 하여 상사분쟁을 중심으로 그 문제점과 해결방안을 검토하고 이를 비상사 분쟁에도 유추적용하는 방향으로 논의한다. 또한, 정부 간 분쟁 발생시 정부가 취하는 조치로 인하여 급작스런 교류 중단이 발생하는 경우, 민간 교류당사자가 입게 될 불측의 손해에 대하 여 민간 교류당사자를 보호할 수 있는 방안을 제안하여 민간의 남북교류협력 사업에 대한 관 심과 참여를 촉진할 수 있도록 한다. So far we have discussed and studied much about how to increase the Inter-Korean exchange and cooperation. But most of such discussions and measures could suddenly erupt like a bubble when inter-Korean relations or international situations are aggravated contrary to our expectations. This paper studies all the issues with focus on the sustainability of the inter-Korean relations. It is advisable that the inter-Korean exchange and cooperation should be based on mutual trust between North and South Korea. Of course, it would take long to establish and strengthen such base. In the process of long trust building efforts, we have seen from time to time insurmountable deadlock and no exchange at all because the North and the South have no effective alternatives. It was typical when the Cheon-an naval ship exploded and sank in the Yellow Sea. Without doubt, it costs too much time and energy to restore the previous relationship. Before we seek the solution, we need to understand current methods to cooperate each other. So we may suggest a better approach to it as a sustainable cooperation method. We will devide the method as two by two phases i.e., government-civil sector and economical-humanitarian way. And finally, we will focus on the solution to maintain the relationship and cooperation in an extreme situation. To this end, we will explore the international arbitration to settle the disputes between the North and the South Korean governments. Also we will review the current inter-Korean agreement to settle commercial disputes between the two Koreas, and a kind of analogy may apply to non-commercial disputes. Further, we will survey what we can do to make a breakthrough if there occurs a unforeseeable deadlock between the North and the South in the future.