성견 2급 치근이개부 병변 치료시 이종골 이식 및 혈소판 농축 혈장의 골재생에 관한 효과

임성빈,이광수,박영채,유형근,신형식,Lim, Sung-Bin,Lee, Kwang-Soo,Park, Young-Chae,You, Hyung-Keun,Shin, Hyung-Shik 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.2

New techniques for regenerating the destructed periodontal tissue have been studied for many years. Current acceptable methods of promoting periodontal regeneration are basis of removal of diseased soft tissue, root treatment, guided tissue regeneration, graft materials, and biological mediators. Platelet Rich Plasma has been reported as a biological mediator which regulates activities of wound healing progress including cell proliferation, migration, and metabolism. The purpose of this study is to evaluate the effects of using the Platelet Rich Plasma as a regeneration promoting agent for furcation involvement defect. Five adult beagle dogs were used in this experiment. The dogs were anesthetized with Ketamin HCl(0.1 ml/kg, IV)and Xylazine hydrochloride($Rompun^{(R)}$, Bayer, 0.1 ml/kg, IM) and conventional periodontal prophylaxis were performed with ultrasonic scaler and hand instruments. With intrasulcular and crestal incision, mucoperiosteal flap was elevated. Following decortication with 1/2 high speed round bur, degree II furcation defect was made on mandibular third(P3), forth(P4) and fifth(P5) premolar, and stopping was inserted. After 4 weeks, stopping was removed, and bone graft was performed. Ca-P was grafted in P3(experimental group I), Combination of Ca-P and plasma rich platelet were grafted in P4(experimental group II), and P5 was remained at control group.Systemic antibiotics(gentamicin sulfate)and anlgesics(phenyl butazone) were administrated intramuscular for 2 weeks after surgery. Irrigation with 0.1% Chlorhexidine Gluconate around operate sites was performed during the whole experimental period except one day immediate after surgery. Soft diets were fed through the whole experiment period. After 4, 8 weeks, the animals were sacrificed by perfusion technique. Tissue block was excised including the tooth and prepared for light microscope with Gomori's trichrome staining. At 4 weeks after surgery, there were rapid osteogenesis phenomenon on the defected area of the Platelet Rich Plasma plus Ca-P BBP group and early trabeculation pattern was made with new osteoid tissue produced by activated osteoblast. Bone formation was almost completed to the fornix of furcation by 8 weeks after surgery. In conclusion, Platelet Rich Plasma can promote rapid osteogenesis during healing of periodontalregeneration.

상수처리 : FI-FFF를 이용한 미생물의 Biofouling Potential 연구

임성빈 ( Seong Bin Lim ),최수훈 ( Soo Hoon Choi ),문지희 ( Ji Hee Moon ),이상엽 ( Sang Youp Lee ),홍승관 ( Seung Kwan Hong ) 한국물환경학회 ( 구 한국수질보전학회 ) 2009 공동 추계학술발표회 Vol.2009 No.-

두뇌 기능 구현을 위한 뇌 정보처리의 공학적 해석

임성빈(Seong-Bin Lim),최우경(Woo-Kyung Choi),김성주(Seong-Joo Kim),하상형(Sang-Hyung Ha),전홍태(Hong-Tae Jeon) 한국지능시스템학회 2005 한국지능시스템학회 학술발표 논문집 Vol.15 No.2

현존하는 정보처리 시스템 중에서 가장 뛰어난 성능을 지니고 있는 것은 인간의 두뇌라고 할 수 있다. 두뇌의 정보처리 메커니즘을 보다 정확하게 구현할 수 있는 시스템은 입력에 대한 정확한 인지 능력, 상황 판단 능력, 학습 및 추론 능력, 출력의 결정 능력 등의 성능 구현은 물론이며, 감정과 비교될 수 있는 시스템의 상태를 평가하여 판단 및 결정에 적용함으로써 매우 뛰어난 지능형 시스템이 될 수 있다. 이러한 뇌 정보처리 시스템의 구현에 앞서 본 논문에서는 생물학적인 대뇌 피질의 구조를 살피고 정보의 처리 영역을 고찰하고 정보의 흐름을 소개하였으며 이를 바탕으로 뇌 정보처리 메커니즘을 공학적인 측면에서 해석해 보았다. 특히, 뇌 영역의 기능 및 구조적인 특징, 정보의 처리과정 등을 공학적으로 해석하였으며 이는 뇌의 기능을 모방한 공학적인 모델을 구현하는데 있어서 기초가 될 것이다.

금속표면처리기업의 생산기술역량이 시장지향성과 경영성과에 미치는 영향

임성빈(Lim Sung-Bin) 실천경영학회 2020 실천경영연구 Vol.15 No.1

In this study, the researcher studied how the technical capabilities in reflection of the needs of the customers influenced the business performance through mediating market orientation. For this, the technical capability was used as the exogenous variable, while market orientation and business performance as the endogenous variables. The data collected in this study were codified and processed using IBM SPSS statistics version 23.0 for windows and AMOS 23.0. And, the results of these analyses were as follows; First, in order to confirm the general characteristics and the approximate statistical values for each survey question, the researcher conducted a frequency analysis accompanied by a descriptive statistical analysis on the survey items. Second, in order to present various questions in an appropriate number of factors, an explorative factor analysis was conducted. And, a confirmatory factor analysis was conducted in order to reverify the convergent validity and determination validity. Third, in order to verify the internal consistence of the variables, Cronbach s was used to conduct a confidence analysis. Fifth, a path analysis was conducted in order to verify the hypothesis drawn from this study.

Fl-FFF를 이용한 미생물이 Biofouling Potential 연구

임성빈 ( Seong Bin Lim ),최수훈 ( Soo Hoon Choi ),문지희 ( Ji Hee Moon ),이상엽 ( Sang Youp Lee ),홍승관 ( Seung Kwan Hong ) 한국물환경학회 2009 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2009 No.-

인공신경망을 이용한 개인 신용평가 알고리즘

임성빈(Sung-Bin Lim),최우경(Woo-Kyung Choi),김성현(Sung-Hyun Kim),김용민(Yong-Min Kim) 한국지능시스템학회 2005 한국지능시스템학회 학술발표 논문집 Vol.15 No.1

최근 우리나라는 가계신용의 급신장과 신용불량의 급증 등으로 개인 신용부문이 금융기관의 건전성 유지에 부정적인 영향을 미치고 있다. 이러한 잠재적 문제를 사전에 방지하기 위해 금융기관 등에서는 개인 신용평가에 대한 수요가 커지고 있는 실정이다. 주어진 데이터로부터의 반복적인 학습 과정을 거쳐 패턴을 분류하고 또한 모델과 학습 방법에 따라 입력변수와 목적변수의 속성이 연속 형이나 이산형인 경우를 모두 다룰 수 있는 신경망 모델은 개개인의 다양하고 복잡한 데이터를 입력변수로 받아서 신용등급을 나누는데 우수한 능력을 보여줄 수 있다. 본 논문에서는 신경망 모델을 이용해 개인의 신용등급을 객관적이고 일률적으로 평가해서 등급을 나누어주는 알고리즘을 제안하고자 한다.

수종의 재생 술식 시행이 매식체 근원심부의 골재생에 미치는 영향

이명자,임성빈,정진형,홍기석,Lee, Myung-Ja,Lim, Sung-Bin,Chung, Chin-Hyung,Hong, Ki-Seok 대한치주과학회 2005 Journal of Periodontal & Implant Science Vol.35 No.2

The successful implantation necessitate tissue regeneration m site of future implant placement, there being severe bone defect. Therapeutic approaches to tissue regeneration in the site have used bone grafts, root surface treatments, barrier membranes, and growth factors, the same way being applied to periodontal tissue regeneration. Great interest in periodontal tissue regeneration has lead to research in bone graft, guided-tissue regeneration, and the administration of growth factors as possible means of regenerating lost periodontal tissue. The blood component separated by centrifuging the blood is the platelet-rich plasma. There are growth factors, PDGF, $TGF{beta}1$, $TGF{beta}2$ and IGF in the platelet-rich plasma. The purpose of this study was to study the histopathological correlation between the use of platelet-rich plasma and the healing of bone defect around implant fixture site. Implant fixtures were inserted and graft materials were placed into the left femur of in the experimental group, while the control group received only implant fixtures. In the first experimental group, platelet-rich plasma and BBP xenograft were placed at the implant fixture site, and the second experimental group had platelet-rich plasma, BBP xenograft, and the e-PTFE membrane placed at the fixture site. The degree of bone regeneration adjacent to the implant fixture was observed and compared histopathologically at 2, 4, and 8 weeks after implant fixture insertion. The results of the experiment were as follows: 1. Bone remodeling in acid etched surface near the implant fixture of all experimental groups was found to be greater than new bone formation. 2. Bone remodeling in acid etched surface distant to the implant fixture of all experimental groups was decreased and new bone formation was not changed. 3. Significant new bone formation in machined surface near the implant fixture of bothl experimental groups was observed in 2 weeks. 4. New bone formation in machined surface distant to the implant fixture of both experimental groups was observed. Bone remodeling was significant in near the implant fixture and not in distant to the implant fixture. The results of the experiment suggested that the change of bone formation around implant. Remodeling in machined surface distant to the implant fixture of both experimental groups, and new bone formation and remodeling near the implant fixture were significant.

성견 발치와에 매식한 2종의 Bovine Bone Powder가 치유에 미치는 영향에 관한 조직학적 연구

박태성,임성빈,정진형,김종여,Park, Tae-Seong,Lim, Sung-Bin,Chung, Chin-Hyung,Kim, Jong-Yeo 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.3

Several extraction cases with advanced bone loss as a result of periodontal disease, root or labial bone fracture, extensive caries, and periapical lesions occur esthetic, functional problems and severe bone loss. Therefore, to treat these cases used several surgical methods and socket preservation among this therapies have been evaluated simple, effective and good prognosis in the implant placement. Socket preservation therapy have been used with barrier membranes or/and graft materials. Deproteinized bovine bone mineral have been evaluated ideal grafting materials. Recently, calcium-phosphate thin film coated bovine bone powders were developed in our country, but the study for these material wasn't reported. When two types of xenograft materials were implanted in extraction sockets of Beagle dogs, the effects of these were analyzed after 4 weeks and 8 weeks histological views. The results of this study were as follows. 1. In control groups, 4 weeks after implantation, the extraction sockets were filled with connective tissue which has dilated vessels and epithelial growth. And after 8 weeks, irregular connective bundles were observed. But new bone formation was not seen. 2. In Bio-Oss groups, epithelial growth was not seen and bone powder was covered with connective tissue fiber. New bone formation was found around the interproximal bone. There was no special change seen after 8 weeks, connective tissue fibers became more regular, and bone growth near bone powder was not made well. 3. In Ca-P BBP groups, epithelial cells didn't grow in the extraction sockets, there was a lot of new bone made around the bone powder after 8 weeks, new bone around bone powder was replaced with mature bone. It is thought that bone powder grafting into the extraction sockets is very useful for conservation of ridge, and Ca-P BBP is more effective in bone formation than Bio-Oss.

임프란트와 지대주 간 내측 연결을 갖는 2종의 임프란트에서 저작압이 임프란트 주위골 내응력 분포에 미치는 영향에 관한 연구

유미경,임성빈,정진형,홍기석,Yoo, Mi-Kyung,Lim, Sung-Bin,Chung, Chin-Hyung,Hong, Ki-Seok 대한치주과학회 2006 Journal of Periodontal & Implant Science Vol.36 No.2

Adequate bone quality and stress distribution to the bone are of decisive importance for implant success. Even though the success rates of dental implants have been high, implant failures do occur. Overloading has been identified as a primary factor behind dental implant failure. The purpose of this study was to theoretically investigate the effect of two types of implants on the stress distribution in poor bone quality. Employing the finite element method, the study modeled a 4.1 mm diameter, 12.0 mm length implant placed in cortical or spongeous bone. A static loading of lOON was applied at the occlusal surface at 0, 30 degrees angle to the vertical axis of the implant. von Mises stresses concentrations in the supporting bone were analyzed with finite element analysis program. The results were as follows; 1. The stresses at the marginal bone were higher under buccal oblique load(30 degrees off of the long axis) than under vertical load. 2. Under buccal oblique load, the stresses were higher at the lingual marginal bone than at the buccal marginal bone, and the differences were almost the same. 3, Under vertical and oblique load, the stress was the highest at the marginal bone and lowest at the bone around apical portions of implant in cortical bone. 4, Under vertical load, Model 1 showed more effective stress distribution than Model 2 irrespective of bone types. On the other hand, Model 2 showed lower stress concentration than Model 1 under buccal oblique load.

혈소판 농축 혈장과 혼합된 자가골 및 이종골 이식재가 치주 조직의 재생에 미치는 효과

김동기,임성빈,정진형,홍기석,Kim, Dong-Gi,Lim, Sung-Bin,Chung, Chin-Hyung,Hong, Ki-Seok 대한치주과학회 2004 Journal of Periodontal & Implant Science Vol.34 No.3

Regeneration of Periodontium with PRP does not only improve regeneration rate and density of bone but have a possibility to estimate faster healing process for soft tissue. And also, autogenous bone and xenogenic bone graft are effective on regeneration of periodontium. The purpose of this study is to evaluate the effectiveness of autogenous bone and xenogenic bone $(BBP^{(R)})$ grafts with the PRP technique on regeneration of periodontium. 52 Generally healthy Pt. who had pocket depth 5mm at any of 6 surfaces of the teeth were in the study at Dept. of Perio. in Dankook Dental Hospital. Open Flap was treated for 18 infra-bony pockets as control group, autogenous bone with PRP was inserted for 25 infrabony pockets as first test group, and $(BBP^{(R)})$ with PRP was inserted for 22 infrabony pockets as 2nd test group. Then evaluation was made after 3 and 6 months 1. There were significant differences between average probing pocket depth and clinical attachment level of 3, 6 months and minimal and maximal attachment level after 6 months each other. 2. There were significant differences in average probing pocket depth of control group and 2nd experimental group between 1 and 6 months. For clinical attachment level and minimal and maximal proving attachment level, there was a significant difference after 6 month of surgery. 3. There was no significant difference between two test groups for average probing depth, clinical attachment level, and minimal and maximal probing attachment level. As the result, PRP with bone graft could be very effective for regeneration of periodontium and there was no difference between xenogenic bone and autogenous bone.