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성인 남성의 혈청 테스토스테론 농도와 전립선 특이항원의 관계에 대한 통합적 고찰
안경주(An, Gyeong-Ju) 한국기초간호학회 2020 Journal of korean biological nursing science Vol.22 No.2
Purpose: The purpose of this study was to review primary research exploring the correlations between the levels of serum testosterone and the prostate-specific antigen (PSA) in healthy men without prostate diseases. Methods: An integrative review was conducted using the Whittemore & Knafle (2005) framework. The keywords, ‘testosterone & prostate-specific antigen’, ‘testosterone & PSA’ and ‘healthy men’ were used to search peer-reviewed publications in six databases. Among 1,959 searched articles, eleven articles were selected after excluding articles that do not meet inclusion criteria. Literature quality was moderate (Level 3). Results: As a result of this study, it was confirmed through the nine articles that healthy adult men showed no significant correlation between the serum testosterone and the PSA. Conversely, two articles presented that the serum PSA correlate positively with the testosterone. In particular, it is inferred that the effect of the serum testosterone and the PSA secreted into a 24-hour circadian rhythm with different amplitudes and slopes would have had great influence. However, it does not consider the factors affecting the testosterone and the PSA, such as race, liver disease, and BMI, so there is insufficient empirical data to clearly explain the relationship between the testosterone and the PSA. Conclusion: The correlation between the serum testosterone and the PSA in healthy adult men is insignificant in relation to the circadian rhythm of the testosterone and the PSA secretion. It is that a large-scale study including various influencing factors using new biochemical indicators such as pro PSA be conducted in the future.
DHEA 투여가 뇌허혈 유발 쥐의 Type I, II 근육에 미치는 효과
안경주,최명애,An, Gyeong-Ju,Choe, Myoung-Ae 한국기초간호학회 2002 Journal of korean biological nursing science Vol.4 No.2
The purpose of this study was to determine the effect of DHEA on Type I(soleus) and II muscles(plantaris, gastrocnemius) in a focal brain ischemia model rat. Thirty-seven male Sprague-Dawley rats with $200{\sim}250g$ body weights were randomly divided into four groups : CINS(cerebral ischemia + normal saline), CIDH(cerebral ischemia + DHEA), SHNS(sham + normal saline), SHDH (sham + DHEA). Both the CINS and CIDH groups were undergone a transient right middle cerebral artery occlusion operation. In the SHNS and SHDH groups, a sham operation was done. DHEA was administered daily at a dose of 0.34mmol/kg, and normal saline was administered daily at the same dose by intraperitoneal injection for 7days after operation. Cerebral infarction in the CINS and CIDH groups was identified by staining with 2% triphenyltetrazolium chloride solution for 60 minutes. The data were analyzed by Kruskal-Wallis test and Mann-Whitney U test using the SPSSWIN 9.0 program. The results were summarized as follows: 1) The muscle weights of soleus(Type I), plantaris and gastrocnemius(Type II) in CINS group were significantly less than those of the SHNS group(p<.01). The muscle fiber cross-sectional area of the CINS group was significantly less than that of the SHNS group in Type I muscle fiber of the soleus and Type II muscle fiber of the plantaris and gastrocnemius(p<.05). The myofibrillar protein content of the CINS group was significantly less than that of the SHNS group in the left gastrocnemius and right soleus(p<.05). 2) The muscle weights of the soleus, plantaris and gastrocnemius except the unaffected side of the plantaris in the CIDH significantly increased compared to those of the CINS group(p<.05). The muscle fiber cross-sectional area of the CIDH group significantly increased compared to that of the CINS group in Type II muscle fiber of the plantaris and gastrocnemius(p<.05). The myofibrillar protein content of the CIDH group significantly increased compared to that of the CINS group in the left soleus(p<.05). 3) On the post-op 8 day, the body weight of the CINS group was significantly less than that of the CIDH, SHNS and SHDH groups(p<.01). Total diet intake of the CINS and CIDH groups was significantly less than that of the SHNS and SHDH groups(p<.01). Based on these results, it was identified that muscle atrophy could be induced during the 7 days after cerebral infarction, and DHEA administration during the early stage of cerebral infarction might attenuate muscle atrophy.
노인의 골다공증과 체질량지수의 관계에 관한 이론적 고찰
안경주,An, Gyeong Ju 한국가정간호학회 2018 가정간호학회지 Vol.25 No.1
Purpose: The purpose of this study was to review the literature to explore the relationship between body mass index (BMI) and bone mineral density (BMD) in elderly using an integrative review. Methods: The keywords 'osteoporosis,' 'body mass index,' and 'bone mineral density' were used to search peer-reviewed publications through four databases. Among 1,389 searched articles, eight articles were selected after excluding those that did not meet the inclusion criteria. Results: Seven articles stated that BMI was positively associated with BMD among elderly. In the elderly, the prevalence of osteoporosis was 25-55.7% in women, and 11-13% in men. Conclusion: This study found that high BMI may be helpful to increase BMD among elderly although the mechanism was not clear. It is necessary to identify BMD and fractures in elderly according to body composition in future research.
서울대 간호학 박사학위논문 분석을 통한 간호학 연구의 경향
안경주,함은미,박광희,강지연,박성희,이희주,류세앙,이명선,김금순,최명애,이소우,이은옥,An, Gyeong-Ju,Ham, Eun-Mi,Park, Kwang-Hee,Kang, Ji-Yeon,Park, Sung-Hee,Lee, Hee-Ju,Ryu, Sea-Ang,Yi, Myung-Sun,Kim, Keum-Soon,Choe, Myoung-Ae,Lee, So-Woo 서울대학교 간호과학연구소 2004 간호학의 지평 Vol.1 No.1
Purpose: The purpose of this study was to identify the trend of nursing research by analyzing doctoral dissertations of nursing college at Seoul National University. Method: The doctoral dissertations used in this study were 69 thesis from 1989 to 2001. The methodological characteristics, theory, philosophy and world view in these thesis were explored. Key words were classified according to metaparadigm and were compared with MeSH term. Result: There were 54 dissertations of quantitative research and 12 dissertations of qualitative research. Most of subjects of the thesis were patients with 20~65 years old. The written consent to participate in research was not described in great part of thesis. As to measurement, questionnaire was most frequent used. In independent variables cognitive nursing interventions were used frequently. Psychosocial variables as a dependent variable were used mainly. In theory level of research, situation-producing research was performed. In type of nursing knowledge according to Caper many dissertations studied about empirical knowledge. More than half of doctoral dissertations used borrowed theory from nursing related disciplines. Most of studies were done within empirical positivism and organic viewpoint. Key words related to the concept of environment among four metaparadigm has been insufficiently studied. English key words in doctoral thesis were out of accordance largely with MeSH term English. Conclusion: These results show that it is necessary to develop the nursing theory for nursing knowledge body.
일개 도시주민의 품위 있는 죽음 태도에 대한 예측 요인
조계화,안경주,김균무,김연자,Jo, Kae Hwa,An, Gyeong Ju,Kim, Gyun Moo,Kim, Yeon Ja 한국호스피스완화의료학회 2012 한국호스피스.완화의료학회지 Vol.15 No.4
목적: 본 상관관계 연구는 품위 있는 죽음과 연명치료중단에 대한 일개도시 성인 남녀의 인식과 태도를 조사하는 한편, 품위 있는 죽음에 대한 그들의 태도를 예측할 수 있는 요인을 확인하기 위해 시도되었다. 방법: 일개 대도시 중 3개 마을의 성인남녀 총 291명을 편의 표출하였다. 구조화된 설문지 문항에는 연명치료중단에 대한 인식, 연명치료중단에 대한 태도, 품위 있는 죽음 척도에 대한 태도 등을 포함하였다. 자료는 기술통계, 피어슨 상관계수 및 다중회귀분석을 이용하여 분석하였다. 결과: 연명치료중단 및 품위 있는 죽음에 대한 태도는 통계학적으로 유의미한 양의 상관관계(r=0.49, P<0.001)를 보였다. 연명치료중단에 대한 태도, 연령, 종교, 연명치료중단의 적절한 프로세스 및 사전의료의향서(Advanced Medical Directives) 등은 품위 있는 죽음에 대한 태도의 중요한 예측 변수들로, 총 분산의 49.3%를 설명할 수 있었다. 결론: 본 연구 결과는 연명치료중단 및 사전의료의향서 프로세스 상에서 간호사의 적절한 역할 등 새로운 의학적 의사결정 시스템을 개발하는 데에 활용될 수 있다. Purpose: This correlation study was performed to examine Korean adults' perceptions and attitudes towards death with dignity and the withdrawal of life sustaining treatment and to identify factors that predict their attitude towards death with dignity. Methods: The study was conducted using convenience sampling of 291 adults from three towns of a metropolitan city in Korea. Data were collected using structured questionnaires which surveyed people's perception about and attitudes towards withdrawal of life sustaining treatment and scaled their attitude towards death with dignity. Data were analyzed by using descriptive statistics, Pearson correlation coefficients and multiple regression. Results: The attitude towards the withdrawal of life sustaining treatment and death with dignity showed a significant positive correlation (r=0.49, P<0.001). For attitudes towards death with dignity, significant predictors were attitudes towards the withdrawal of life sustaining treatment, age, religion, a proper withdrawal process and advanced medical directives, which explained 49.3% of total variance. Conclusion: The results of this study may contribute to development of a new medical decision-making system including nurses' appropriate roles in the process of withdrawing life sustaining treatment and advanced medical directives.
수술실간호사와 병동간호사의 감염관련특성과 환자안전문화가 혈행성 감염예방 인식에 미치는 영향
전해옥(Jeon, Hae Ok),안경주(An, Gyeong Ju),이종희(Lee, Jong Hee),이경미(Lee, Kyoung Mi) 한국기초간호학회 2021 Journal of korean biological nursing science Vol.23 No.1
Purpose: This study aimed to identify the factors influencing infection-related characteristics and patient safety culture on awareness of blood-borne infection prevention between operating room nurses and general ward nurses. Methods: Participants were 198 nurses(operating room nurses 98 and general ward nurses: 100) working at three general hospitals and three university hospitals in three cities. Data were collected using a structured questionnaire from September 11 to October 14, 2020. Data were analyzed using descriptive statistics, t-tests, ANOVA, Pearson’s correlation coefficient, and multiple regression with IBM SPSS/WIN 26.0 program. Results: Typically, 39.8% of nurses in the operating room and 24.0% of ward nurses experienced injuries such as needles and sharp instruments used by the patient. The awareness of patient safety culture was identified to be higher for the ward nurses. Factors influencing the awareness of blood-borne infection prevention in operating room nurses were patient safety culture and wearing protective equipment for infection prevention while nursing infected patients. Moreover, the explanatory power of these variables was 19.4%. In general ward nurses, the patient safety culture was identified as a significant predictor, which accounted for 16.5% of awareness of blood-borne infection prevention. Conclusion: To prevent hospital infection, a strategy is needed to improve the level of awareness of blood-borne infection prevention and patient safety culture of operating room nurses. To this end, the difference in infection-related characteristics and influencing factors between the operating room nurses and the general ward nurses should be considered and planned.