안면신경마비 동물모델에서 전기활성고분자를 이용한 눈 깜박임 기능의 회복

권성근,성명훈,김광현,김희찬,Kwon, Seong-Keun,Sung, Myung-Whun,Kim, Kwang-Hyun,Kim, Hee-Chan 대한기관식도과학회 2006 大韓氣管食道科學會誌 Vol.12 No.2

There have been numerous modalities to recover blink function of orbicularis oculi muscle in patients with facial paralysis. However, there is still no optimal method for reanimation of eyelid. In this study, we tried to recover blink function of paralyzed rabbit's eyelid with the ion polymer metal composite (IPMC) which is one of the electroactive polymers that is spotlighted as artificial muscle. We manufactured IPMC by plating the platinum over perfluorosulphonic acid polymer ($Nafion^{(R)}$). IPMC was coated by Norland optical adhesive for the purpose of insulation and keeping it from dry. IPMC modifications by roughening the surface of Nafion, repetitive plating (maximum 4 times) with platinum, and lengthening the width of IPMC were done. The facial paralysis was induced in the rabbit by sectioning of facial nerve at the main trunk. After minimum period of 4 weeks, IPMC was inserted in the paralyzed rabbit's eyelid. By modification, the force generated by IPMC was enhanced. Restoration of blink function in paralyzed rabbit was achieved on electrical stimulation of the IPMC by 5 voltage direct current. IPMC can be promising option for facial reanimation, but further studies are needed to enhance the efficiency of IPMC.

이하선 종양으로 오인된 방선균증 1예

권성근(Seong Keun Kwon),지준혁(Jun Hyuk Chi) 대한두경부종양학회 2010 대한두경부 종양학회지 Vol.26 No.2

Actinomycosis is an unusual granulomatous infection caused by gram-positive anaerobic bacteria called Ac-tinomyces species(predominantly Actinomyces israelii), which is a common and normally nonpathogenic orga-nism found in the nose and throat. The three major clinical presentations of actinomycosis include the cervico-facial(the most common, 55%), thoracic, and abdominopelvic region. Actinomycosis typically has a chronic, in-dolent course characterized by swelling and induration of the soft tissues and eventual spontaneous drainage through multiple sinus tracts. Actinomycosis is difficult to diagnose because of variable presentation mimicking neo-plasm and fastidious nature of the organism in culture. We present a case of actinomycosis in the parotid tip area which was mistaken for a salivary tumor.

후두에 발생한 혈관평활근종 1예

권성근(Seong Keun Kwon) 대한두경부종양학회 2007 대한두경부 종양학회지 Vol.23 No.2

Angioleiomyomas are a vascular subtype of leiomyomas or benign smooth muscle tumors. The majority of these tumors occur in the extremities. Angioleiomyoma of the larynx has been reported but is exceedingly rare. Laryngeal angiomyomas can present with hoarseness, dyspnea, or globus sensation, and often misdiagnosed as asthma. We report a case of a 74-year old man with laryngeal angioleiomyoma misdiagnosed as asthma.

부서진 기관튜브로 발생한 소아 기관지 이물

한민석,권성근,Han, Min-Seck,Kwon, Seong-Keun 대한기관식도과학회 2010 大韓氣管食道科學會誌 Vol.16 No.1

Fracture of tracheostomy tube with subsequent migration into the tracheobronchial tree is rare, but tracheobronchial foreign body in child carries the potentially fatal risk of respiratory obstruction, We report a case of a 5-year-old girl who had aspirated a fractured tracheostomy tube which was removed under rigid bronchoscope.

성문 상부에 발생한 혼합형 혈관종

이은경,권성근,Lee, Eun-Kyeung,Kwon, Seong-Keun 대한기관식도과학회 2010 大韓氣管食道科學會誌 Vol.16 No.2

Laryngeal hemangioma occurs mostly in infantile patients and infantile hemangiomas can be frequently seen in the subglottic area. So, respiratory distress is a main symptom in this entity. But adult hemangiomas are rare and can be seen in different locations such as in epiglottis, aryepiglottic fold, arytenoids and false and true vocal folds. Authors experienced a case of mixed hemangioma at the right aryepiglottic fold in a 42 years-old-man who was presented with snoring, throat foreign body sense for 3 months. So, we report this case with a review of the literature.

후두부에 발생한 과오종 1예

김보해,권성근,Kim, Bo Hae,Kwon, Seong Keun 대한후두음성언어의학회 2012 대한후두음성언어의학회지 Vol.23 No.2

Hamartoma is benign pathologic lesion that looks like a neoplasm. But actually hamartoma is derived from congenital developmental errors of mature tissue. That is a focal overgrowth of normal tissue components. Hamartomas have been reported as arising anywhere in the body, but rarely has it been found in the head and neck region. Above all, laryngeal hamartoma has been described few times. We report an unusual case of hamartoma located in the larynx. Epiglottis mass was found incidentally by gastrofibroscopic examination. After the mass was excised by $CO_2$ laser, pathologic diagnosis has confirmed the mass as hamartoma.

장기간 기관절개공을 유지한 소아 환자들에서의 기도 세균집락에 관한 연구: 균동정 부위와 시차 간의 차이 비교

한승훈,김영석,권성근,Han, Seung Hoon,Kim, Young Seok,Kwon, Seong Keun 대한후두음성언어의학회 2021 대한후두음성언어의학회지 Vol.32 No.1

Background and Objectives Tracheostomy lead to persistent bacterial colonization of the respiratory tract. Surgical site infection and restenosis by the pathogenic bacteria is the most fatal complication after open airway surgery. The aim of this study is to describe the culture results of larynx and tracheostoma in patients with tracheostomy and the preoperative, intraoperative culture results in patients underwent open airway surgery. Materials and Method A retrospective review was performed on 18 patients who underwent culture between 2017 and 2019. Results Pseudomonas or antibiotic resistance bacteria were identified in 11 patients out of 18 patients (61.1%); Ceftriaxone-resistant Streptococcus (38.9%), Pseudomonas (33.3%), Methicillin-resistant Staphylococcus aureus (16.7%), extended-spectrum β-lactamases (ESBL) producing Klebsiella pneumoniae (11.1%). Among 18 patients, 6 patients showed the different culture result between larynx and tracheostoma. In 4 out of 10 patients who underwent open airway surgery, the bacteria were not identified before surgery, but the bacteria were isolated in the intraoperative culture. In one patient, the bacteria detected intraoperatively were different from those detected before surgery. Conclusion Preoperative respiratory tract culture and usage of perioperative antibiotics according to the culture are necessary. It is crucial to verify the bacterial culture in both tracheostoma and larynx. And it should be performed immediately before open airway surgery.

기관식도 침범이 있는 분화 갑상선암의 치료

하정훈,정은정,노동환,권성근,성명훈,김광현,Jeong-Hun Hah,M.D.,Eun-jung Jung,M.D.,Dong Hwan Roh,M.D.,Seong Keun Kwon,M.D.,Myung-Whun Sung,M.D. and Kwang Hyun Kim,M.D. 대한갑상선-내분비외과학회 2004 The Koreran journal of Endocrine Surgery Vol.4 No.2

Purpose: Well differentiated thyroid carcinomas are mostly curable diseases. Invasion of aerodigestive tract by thyroid carcinoma is rare. However, it is considered as a poor prognostic indicator of survival. Some studies showed that local invasion of thyroid carcinoma was the cause of death in many patients. Therefore, adequate local control of the tumor is critical to avoid the mortality as well as the morbidity of the disease. To find proper and adequate treatment modality of locally invasive thyroid carcinoma, we evaluated treatment modalities and outcomes in the patients with thyroid carcinoma with invasion of aerodigestive tract. Methods: Forty patients with thyroid carcinoma invading aerodigestive tract who were treated from July 1989 through July 2002 were reviewed retrospectively. Results: Direct intraluminal invasion of the thyroid carcinoma requires definitive resection of the aerodigestive tract. In case that the extent of tumor was thought to be limited to perichondrium or extraluminal invasion, tracheal shaving procedure was performed. Five-year and 10-year local control rates were 81.6% and 57.4%, respectively. Disease-specific survival rates of 5-year and 10-year were 90.1% and 81.1%, respectively. Conclusion: For the successful treatment of invasive thyroid carcinoma, the resection of the functional structures or the aerodigestive tract should be determined prudently according to the presence of the intraluminal invasion. (Korean J Endocrine Surg 2004;4:101-105)

인두 이물감을 호소하는 환자에서 식도 내 공기에 대한 연구

심예지,남동우,김보해,진영주,유윤종,김민수,정은재,권성근,하정훈,권택균,Shim, Ye Ji,Nam, Dongwoo,Kim, Bo Hae,Jin, Young Ju,Ryu, Yoon-Jong,Kim, Min-Su,Chung, Eun-Jae,Kwon, Seong Keun,Hah, J Hun,Kwon, Tack-Kyun 대한후두음성언어의학회 2015 대한후두음성언어의학회지 Vol.26 No.2

Background and Objectives : The etiology of globus pharyngeus remains uncertain. It has been known there is a relationship between the presence of air bubbles in esophagus and GERD symptoms. The aim of this study is to identify relationship between the globus symptom and the presence of air column in esophagus. Subjects and Methods : The study population consisted of 46 patients who underwent CT scan as part of evaluation for globus. Controls were chosen from the population consisted of patients with lymphadenopathy who underwent CT scan. The correlation between the presence of globus symptom and diameter, volume, and position of the air column was assessed using t-test. Reproducibility of diameter and volume of the esophageal air column was analyzed using intraclass correlation coefficient. Results : In study group, the mean volume of the air column was $769.56{\pm}983.08mm^3$, the mean diameter was $8.24{\pm}4.90mm$, the mean distance from the inferior border of posterior lamina of cricoid cartilage was $88.86{\pm}28.01mm$. In control group, $682.18{\pm}767.28mm^3$, $8.37{\pm}5.50mm$, $88.34{\pm}21.06mm$, respectively. There were no differences of diameter, volume and distance of the air column between the two groups. We failed to obtain acceptable reliability when we compare the diameter and the volume of the esophageal air column. Conclusion : There was no relationship between air column of esophagus and presence of globus symptom. And the measurement of diameter and volume of the esophageal air column change over time and it should be considered in a further study.

두경부암 환자의 대체요법 이용 실태

김광현(Kwang Hyun Kim),정은정( Eun Jung Jung),하정훈(Jeong Hun Hah),권성근(Seong Keun Kwon),성명훈(Myung Whun Sung) 대한두경부종양학회 2005 대한두경부 종양학회지 Vol.21 No.1

Background and Objectives: The popularity of complementary and alternative medicine(CAM) has grown at an astonishing rate in recent years. Because patients are interested in CAM and want to use it, physicians also should be concerned about CAM and know about the current situation of its usage. In this study, we tried to determine the prevalence of CAM use in the patients with head and neck cancer and correlate with demographics and tumor characteristics. Materials and Methods: A total of 87 patients with head and neck cancer previously treated with surgery at Seoul National University Hospital from March through June, 2004 were enrolled in this study. The patients were completed, questionnaire about the use of CAM and demographic information. Tumor characteristics were obtained from the patient's medical records. Results: Of the 87 patients, 33 patients(37.9%) use at least one CAM. There was no statistically significant correlation between patient's data and prevalence of CAM use. Of those patients using CAM, 16(48.5%) of 33 were using 2 or more therapies. The majority of agents used by patients in this study are mushrooms such as Phellinus and Reishi, followed by dietary therapy. A majority(60.6%) of patients were introduced to alternative medicine by friends or family members. Conclusion: Considerable cancer patients use CAM. Head and neck oncologists should inform themselves about CAM to counsel and educate the patients. Further scientific investigations on promising CAM agents may help advance cancer treatment.