http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
한약복합추출물 HT008의 제조방법에 따른 항염증 효능 및 성분함량 비교연구
이동헌 ( Dong Hun Lee ),송정빈 ( Jung Bin Song ),송미경 ( Mi Kyung Song ),( Bhakta Prasad Gaire ),박주연 ( Ju Yeon Park ),김애홍 ( Ai Hong Jin ),최호영 ( Ho Young Choi ),김호철 ( Ho Cheol Kim ) 대한본초학회 2013 大韓本草學會誌 Vol.28 No.4
Objectives : The biological activities and compound contents of herbal medicine vary depending on manufacturing processes. In this study, we compared anti-inflammatory effects and compound contents of three kinds of multi-herbal extract HT008 produced by different manufacturing processes in order to determine chemical and biological equivalence. Methods : HT008 was produced by three different manufacturing methods: 1. Freeze dried extract of Eleutherococcus senticosus, Scutellaria baicalensis and Angelica sinensis (HT008 FD), 2. Spray dried extract of E. senticosus and S. baicalensis combined with reflux extract of A. sinensis (HT008 SD), 3. Spray dried extract of E. senticosus and S. baicalensis combined with supercritial fluid extract of A. sinensis (HT008 SF). Anti-inflammatory effects were evaluated using acetic acid induced pain model and λ-carageenan induced paw edema model. Compound contents were evaluated by HPLC quantitative analysis of standard compounds of HT008, eleutheroside E, baicalin, z-ligustilide. Results : HT008 FD, HT008 SD and HT008 SF significantly decreased acetic acid induced pain index and λ -carrageenan induced paw edema volume compared with that of control group. There was no significant difference in efficacy among the HT008 FD, HT008 SD and HT008 SF. Standard compound contents of HT008 FD, HT008 SD and HT008 SF were quantified within the range of Korean pharmacopoeia or other research. Conclusions : Three different manufacturing methods of multi-herbal extracts have been developed without noticeable difference in the efficacy or compound contents. The results might be used to establish manufacturing process and industrialization of herbal extracts.
崔在亨(Jae-Hyeong Choi),崔眞郁(Jin-Wook Choi),李海根(Haigun Lee),宋廷彬(Jung-Bin Song),金海鍾(Hae-Jong Kim),成耆哲(Ki-Chul Seong),金相賢(Sang-Hyun Kim) 대한전기학회 2009 전기학회논문지 Vol.58 No.1
Recently, for improvement of the magnetic field of high temperature superconductor (HTS) apparatus, many studies investigating on operating in the range of 20 - 65 K with liquid helium or the conducting method using cryocooler are actively reviewed. Also, the cooling method using solid nitrogen as cryogen is being suggested. Since the nitrogen has very large specific heat in solid state, it is expected that it can be operated for a long time without a continuous supply of cooling energy. However, there are still insufficient data on the characteristics of solid nitrogen such as thermodynamic properties and liquid-solid phase change. Especially, there was almost no study done on the electrical insulation properties of solid nitrogen so far. In this study, solid nitrogen to find the electrical characteristics was made by using cryocooler and cryostat, and investigated the flashover discharge and breakdown. The results of this study will be useful as a basic data for electrical insulation design of the HTS system using solid nitrogen as cryogen.