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운동이 일부 남녀 대학생들의 혈청과 뇨중 칼슘, 마그네슘 및 아연함량에 미치는 영향
임상선,김형락,차연수,안창범,정복미 여수대학교 1997 論文集 Vol.11 No.2
This study investigated the effect of regular exercise on mineral status in college students. Mineral status for calcium, magnesium, and zinc was evaluated prior to beginning the study and again after 35 days of exercise training for 30 minutes per day. The results obtained were summarized as follows: 1) Serum concentrations of calcium and magnesium were decreased in female subjects but were not affected in males. 2) Urinary excretion of calcium and magnesium was significantly increased in male subjects but unchanged in females. 3) Serum and urinary zinc concentrations were not affected in either male or female subjects. These results suggest that regular exercise may have different effect on calcium and magnesium in humans, depending on gender.
Youn, Dong-Ye,Lee, Dong-Hyoung,Lim, Mi-Hyun,Yoon, Jung-Sook,Lim, Ji Hee,Jung, Seung Eun,Yeum, Chung Eun,Park, Cheol Whee,Youn, Ho-Joong,Lee, Jae-Seon,Lee, Seong-Beom,Ikawa, Masahito,Okabe, Masaru,Tsuj American Physiological Society 2008 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND M Vol.295 No.6
<P>Bcl-2 interacting cell death suppressor (Bis), also known as Bag3 or CAIR-1, is involved in antistress and antiapoptotic pathways. In addition to Bcl-2, Bis binds to several proteins, suggesting it has diverse functions in normal and pathological conditions. To better define the physiological function of Bis in vivo, we developed bis-deficient mice with a cre-loxP system. Targeted disruption of exon 4 of the bis gene was demonstrated by Southern blotting and PCR, and Western blotting showed that no intact or truncated Bis protein was synthesized in bis(-/-) mice. While heterozygotes were fertile and appeared normal, Bis-deficient mice showed growth retardation and died by 3 wk after birth. The relative weight of the thymus and spleen was reduced and the total numbers of white blood cells, splenocytes, and thymocytes were significantly reduced compared with wild-type littermates. Serum profiles indicated significant hypoglycemia as well as decrease in triglyceride and cholesterol levels. Expression profiles of metabolic genes indicated that gluconeogenesis and beta-oxidation are activated in the liver of bis(-/-) mice. This activation, as well as a decrease in peripheral fat and an induction of fatty liver, appears to be an adaptive response to hypoglycemia. Our study reveals that the absence of Bis has considerable influences on postnatal growth and survival, possibly due to a nutritional impairment.</P>
임미희 ( Mi-hee Lim ),안세연 ( Se-youn Ahn ),이은선 ( Eun-sun Lee ),정재연 ( Jae-yeon Jung ),한지연 ( Ji-youn Han ),황윤숙 ( Yoon-sook Hwang ),한수진 ( Su-jin Han ) 한국치위생학회(구 한국치위생교육학회) 2020 한국치위생학회지 Vol.20 No.6
Objectives: This study aimed to check the effect of preschool visiting oral health education programs and provide baseline data for an oral health education program that suggests the necessity of oral health education in children’s living places. Methods: The preschool visiting oral health education was conducted with the parents of 3-year-old and 4-year-old children at a preschool in the jurisdiction of the Seoul Metropolitan Office of Education, with teachers observing the education, and oral health educators to examine the effect of the oral health education, the effectiveness of the education, the status of oral health care, and the degree of cooperation for the education. Results: Regarding oral health behaviors after the education program, the attitude toward brushing teeth after food intake increased from 2.86 to 3.17 and thinking of the relationship with dental caries and eating food increased from 2.57 to 2.90. The satisfaction with the children’s health education was very high at over 4.9 points in most items. The teachers’ interest in children’s oral care was 4.26 points, and the degree of their cooperation for education was 4.41 points; 96.4% responded that they were willing to conduct reeducation. Conclusions: Children’s oral health education should be conducted steadily and repeatedly.
이선미 ( Sun Mi Lee ),류정숙 ( Jung Sook Yoo ),안세연 ( Se Youn Ahn ),임미희 ( Mi Hee Lim ),한지연 ( Ji Youn Han ),전미경 ( Mi Kyoung Jun ),이현옥 ( Hyun Ok Lee ),원영순 ( Young Soon Won ) 한국치위생과학회 2015 치위생과학회지 Vol.15 No.3
This study was conducted to provide baseline data which could suggest a direction of role based efficient integrated clinical education by avoiding duplicate of contents through analyzing clinical courses. Among the 7 clinical courses, orthodontics and periodontology were the most published subjects which were published in 5 kinds of books and dental materials was the least published subject which was published in 2 kinds of books on investigation of overlapping contents based on titles that appeared on chapters and verses of all textbooks for clinical courses. Dental implant was covered in 4 subjects such as oral maxillofacial surgery, prosthodontics, periodontology and dental materials which was the most number. Other overlapping contents were restoration treatment, occlusion and malocclusion, temporomandibular joint diseases, anesthesiaㆍsedation, tooth trauma, systemic disease and dental treatment, dental casting, isolation techniques, tooth bleaching, pulp protection, gingivitisㆍperiodontitis, tooth development, etc. Reviews of textbooks of clinical courses should be conducted in a detailed manner by systematic, various studies in order to improve quality of the textbooks.
Effect of Modulation of hnRNP L Levels on the Decay of bcl-2 mRNA in MCF-7 Cells
Lim, Mi-Hyun,Lee, Dong-Hyoung,Jung, Seung-Eun,Youn, Dong-Ye,Park, Chan-Sun,Lee, Jeong-Hwa The Korean Society of Pharmacology 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.1
It has been shown that CA repeats in the 3'-untranslated region (UTR) of bcl-2 mRNA contribute the constitutive decay of bcl-2 mRNA and that hnRNP L (heterogenous nuclear ribonucleoprotein L) interacts with CA repeats in the 3'-UTR of bcl-2 mRNA, both in vitro and in vivo. The aim of this study was to determine whether the alteration of hnRNP L affects the stability of bcl-2 mRNA in vivo. Human breast carcinoma MCF-7 cells were transfected with hnRNP L-specific shRNA or hnRNP L-expressing vector to decrease or increase hnRNP L levels, respectively, followed by an actinomycin D chase. An RT-PCR analysis showed that the rate of degradation of endogenous bcl-2 mRNA was not affected by the decrease or increase in the hnRNP L levels. Furthermore, during apoptosis or autophagy, in which bcl-2 expression has been reported to decrease, no difference in the degradation of bcl-2 mRNA was observed between control and hnRNP L-knock down MCF-7 Cells. On the other hand, the levels of AUF-1 and nucleolin, transacting factors for ARE in the 3'UTR of bcl-2 mRNA, were not significantly affected by the decrease in hnRNP L, suggesting that a disturbance in the quantitative balance between these transacting factors is not likely to interfere with the effect of hnRNP L. Collectively, the findings indicate that the decay of bcl-2 mRNA does not appear to be directly controlled by hnRNP L in vivo.