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( Hye Ree Jang ),( Byoung Jin Min ),( Jung Mi Byun ),( Young Nam Kim ),( Kyung Bok Lee ),( Moon Su Sung ),( Ki Tae Kim ),( Dae Hoon Jeong ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
목적: Pelvic, para-aortic lymph node (PALN) evaluation is a major component of the surgical staging procedure for endometrial and ovarian cancer. The surgical goals of the lymph node dissection are to define the extent of disease and to improve survival by removing metastatic lymph nodes. However, there were many controversies upon levels of lymph node dissection. Aim : To evaluate the importance of para-aortic lymphadenectomy (PAL) up to the level of renal vessels, and to determine the extent of PAL with endometrial and ovarian cancer. 방법: A retrospective study about endometrial and ovarian cancer who had underwent surgical staging or debulking surgery between January 2014 and June 2016 at Busan Paik hospital was conducted. 결과: One hundred and twelve patients with endometrial and ovarian cancer underwent PAL as a part of debulking surgery. Twenty patients (17.8%) had pelvic lymph node metastasis; 16 patients (14.2%) had pelvic and PALN metastasis and 4 patients (3.6%) had only pelvic lymph node metastasis. Six patients (5.3%) had no pelvic lymph node metastasis but had PALN metastasis. Forty-six patients within the same group (41%) underwent PAL up to the level of renal vessels and separate lymph node by two groups; upper and lower area of inferior mesenteric artery (IMA). In this group, 9 patients (19.5%) had PALN metastasis; 6 patients (13%) had both upper and lower area of IMA lymph node metastasis (5 ovarian cancer,1 endometrial cancer), 2 patients (4.3%) had no pelvic lymph node metastasis but had lower area of IMA lymph node metastasis (all 2 ovarian cancer) and 1 patient (2.1%) had only upper area of IMA lymph node metastasis(1 ovarian cancer). 결론: PAL up to the renal vessels may help to find gross metastasis and apply appropriate adjuvant treatment. Moreover, some patients turned out to have lymph node metastasis above the level of IMA without metastasis below. In conclusion, the PALN sampling up to the level of the renal vessels is a hard but necessary workup for gynecologist.
Hybrid leiomyosarcoma/rhabdomyosarcoma with asymptomatic pulmonary metastasis : A Case Report
( Hye Ree Jang ),( Yong Hee Park ),( Soo Jin Jung ),( Hyo Jung An ),( Young Nam Kim ),( Dae Hoon Jeong ),( Moon Su Sung ),( Kyung Bok Lee ),( Ki Tae Kim ),( Jung Mi Byun ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
We report a rare composite uterine neoplasm composed of leiomyosarcoma and pleomorphic rhabdomyosarcoma. An uncommon uterine malignancy was encountered in a 55-year-old female who presented with vaginal bleeding and asymptomatic pulmonary metastasis. The patient was diagnosed with a high grade sarcoma with highly suggestive of pleomorphic rhabdomyosarcoma after an endometrial sampling. The patient underwent a hysterectomy/salpingo-oophorectomy, with complete surgical staging, and was found to have a tumor invading >50% of the myometrium with no metastases to the lymph nodes and soft tissues.The final pathology revealed the leiomyosarcoma with focal rhabdomyosarcomatous differentiation with extensive necrosis. In addition, the patient was diagnosed metastatic lung cancer by CT-guided lung biopsy. She receives adjuvant chemotherapy with modified CyVADIC (cyclophosphamide, vincristine, doxorubicin, dacarbazine) and radiotherapy for metastatic lung cancer. This represents a rare example of a uterine mesenchymal neoplasm exhibiting various lines of differentiation. Key words: Leiomyosarcoma, Rhabdomyosarcoma, Lung metastasis.
복부 브레이싱 운동이 20대 성인의 호흡기능에 미치는 영향에 관한 예비연구
장혜리(Hye-Ree Jang),황보각(Bogak Hwang),이도연(Do-Youn Lee) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.7
요부안정화 운동은 척추 주변 근육과 복부 근육을 강화시켜 최근 임상에서 많이 사용하는 운동 방법이지만 호흡기능에 어떠한 영향을 미치는지에 대한 연구는 부족한 실정이다. 이에 본 연구에서는 대표적인 요부안정화 운동인 복부브레이싱 운동이 정상 성인의 호흡기능에 효과적인지를 알아보고자 실시하였다. 20대 성인 40명을 대상으로 각각 복부브레이싱 운동을 25분간 실시하는 실험군과 일상생활을 25분간 하는 대조군으로 무작위 배치하였다. 호흡기능의 변화량을 비교하기 위하여 노력성 폐활량, 1초간 노력성 호기량과 최대호기유속을 통해 폐기능 검사를 하였고, 호흡압력의 변화량을 알아보기 위해 최대 호기압력과 최대 흡기압력을 측정하였다. 본 연구의 실험 결과 실험군에서 폐기능과 호흡압력 모두 유의하게 증가되었고(p<.05), 그룹 간 비교에서는 최대 흡기압력을 제외한 나머지 수치에서 유의한 차이가 있었다(p<.05). 이러한 결과는 복부 브레이싱 운동이 호흡기능을 향상시키기 위한 효과적인 운동으로 제시될 수 있다고 사료된다. Lumbar stabilization exercise is a popular exercise method in recent clinicians, as it strengthens muscles around the spine and abdominal muscles, but there is a lack of research on the effects of pulmonary function and respiratory pressure. So, this study examined whether abdominal bracing exercise, a typical lumbar stabilization exercise, was effective in pulmonary function and respiratory pressure. In this study, a total of 20’s 40 subjects were recruited and randomly divided into an abdominal bracing exercise group(n=20) and control group(n=20). Abdominal exercise group underwent 25 minutes of exercise. Pulmonary function and respiratory pressure values were measured to analyze respiratory function. As a results of the experimental group, there were significant improvements in FVC, FEV1, PEF and MEP(p<.05) and there was a significant difference in the comparison between groups, except the MIP. These results suggest that abdominal bracing exercise can be presented as effective exercises to improve respiratory function.
Benzomalvin E, an indoleamine 2,3-dioxygenase inhibitor isolated from Penicillium sp. FN070315
Jang, Jun-Pil,Jang, Jae-Hyuk,Soung, Nak-Kyun,Kim, Hye-Min,Jeong, Sook-Jung,Asami, Yukihiro,Shin, Kee-Sun,Kim, Mee Ree,Oh, Hyuncheol,Kim, Bo Yeon,Ahn, Jong Seog Springer Science and Business Media LLC 2012 Journal of antibiotics Vol.65 No.4
장혜진(Hye Jin Jang),양리주(Ree Joo Yang),최종명(Jong Myoung Choi) 충북대학교 생활과학연구소 2008 생활과학연구논총 Vol.12 No.1
This study was performed to investigate relationships between body image and color preferences for summer T-shirts among university students. A questionnaire survey was conducted on 268 university students in the Cheongju area, Korea. Frequency, descriptive analysis, factor analysis, x² and t-tests were used for data analysis. The results were as follows: Students" body image consisted of three factors: Appearance enhancement, weight control, physical attractiveness. There were significant gender differences in the three factors of body image. Female students were more highly interested in appearance enhancement and weight control of body image, but male students were more highly interested in physical attractiveness in their body image. Regardless of gender, most students owned white, red, blue and yellow color of summer T-shirts. The students with higher interests in appearance enhancement and physical attractiveness preferred expanding color T-shirts, like red, yellow and white color. Also, the more students had interests in appearance enhancement, the more they preferred vivid and strong color T-shirts for summer.
Kang, Jung Ae,Kim, Hye Rim,Yoon, Sunhye,Nam, You Ree,Park, Sang Hyun,Go, Kyung-Chan,Yang, Gwang-Wung,Rho, Young-Hwan,Park, Hyo-Suk,Jang, Beom Su The Korean Association for Radiation Protection 2016 방사선방어학회지 Vol.41 No.3
Background: Ionizing radiation causes cellular damage and death through the direct damage and/or indirectly the production of ROS, which induces oxidative stress. This study was designed to evaluate the in vivo radioprotective effects of a bio-active material coated fabric (BMCF) against ${\gamma}$-irradiation-induced cellular damage in Sprague-Dawley (SD) rats. Materials and Methods: Healthy male SD rats wore bio-active material coated (concentrations in 10% and 30%) fabric for 7 days after 3 Gy of ${\gamma}$-irradiation. Radioprotective effects were evaluated by performing various biochemical assays including spleen and thymus index, WBC count, hepatic damage marker enzymes [aspartate transaminase (AST) and alanine transaminase (ALT)] in plasma, liver antioxidant enzymes, and mitochondrial activity in muscle. Results and Discussions: Exposure to ${\gamma}$-irradiation resulted in hepatocellular and immune systemic damage. Gamma-irradiation induced decreases in antioxidant enzymes. However, wearing the BMCF-30% decreased significantly AST and ALT activities in plasma. Furthermore, wearing the BMCF-30% increased SOD (superoxide dismutase) and mitochondrial activity. Conclusion: These results suggest that wearing BMCF offers effective radioprotection against ${\gamma}$-irradiation-induced cellular damage in SD rats.
Choi, Go Eun,Jang, Mi Hee,Song, Eun Ju,Jeong, Seok Hoon,Kim, Jae-Seok,Lee, Wee Gyo,Uh, Young,Roh, Kyoung Ho,Lee, Hye Soo,Shin, Jong Hee,Ryoo, Nam Hee,Kim, Young Ree,Jeong, Joseph,Kim, Jee Hee,Lee, Sun The Korean Academy of Medical Sciences 2010 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.25 No.12
<P>The Beijing family of <I>Mycobacterium tuberculosis</I> has been emerging in the world. However, there are few nationwide data of genotypic distribution in Korea. This study aimed to identify the genotypic diversity of clinical isolates of <I>M. tuberculosis</I> and to demonstrate the population of Beijing family in Korea. We collected 96 clinical <I>M. tuberculosis</I> isolates from 11 university hospitals nationwide in Korea from 2008 to 2009. We observed 24 clusters in IS<I>6110</I>-RFLP analysis and 19 patterns in spoligotyping. Seventy-five isolates were confirmed to be Beijing family. Two isolates of the K strain and 12 isolates of the K family strain were also found. We found that drug resistance phenotypes were more strongly associated with Beijing family than non-Beijing family (<I>P</I>=0.003). This study gives an overview of the distribution of genotypes of <I>M. tuberculosis</I> in Korea. These findings indicate that we have to pay more attention to control of <I>M. tuberculosis</I> strains associated with the Beijing family.</P>
( Da Hyun Kim ),( Hye Ree Jang ),( En Bee Cho ),( Jeong Eun Jeong ),( Jung Mi Byun ),( Dae Hoon Jeong ),( Kyung Bok Lee ),( Moon Su Sung ),( Ki Tae Kim ),( Young Nam Kim ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
목적: The colonization rate for GBS infection in pregnant women have been reported to vary from 4.8% up to 11.5% in Korea. These discrepancies might result from different sampling procedure and media among studied centers. Recently, the Centers for Disease Control and Prevention (2010) recommended a universal prenatal screening strategy to identify GBS carrier and intrapartum antimicrobial prophylaxis (IAP) with positive cultures. We aimed to analyze the prevalence of maternal GBS colonization and vertical transmission under a universal prenatal screening using selective culture media. 방법:We included 830 pregnant women who visited and delivered at Busan Paik Hospital between January 2015 and June 2016. The specimens for GBS culture were obtained from both the lower vagina and perianal area in women who were admitted for threatened preterm delivery or who visited at our clinic for antenatal care at 35-37 weeks of gestation. These swabs were then inoculated into Todd-Hewitt broth and CHROMagar StrepB agar. IAP were given to women with rectovaginal GBS-positive cultures under CDC guideline. 결과: Among the 830 cultured pregnant women, 94 (11.3%) were positive for GBS colonization. 22 (23.4%) were positive culture from lower vagina, 33 (35.1%) from perianal area and 39 (41.5%) from both. Maternal characteristics including age, delivery mode and time were not different between positive and negative GBS groups. GBS positive rate was also not differ between preterm and full-term delivery groups. Among 115 neonates who were born from GBS colonized women, 37 (32.2%) neonates had neonatal sepsis, however, GBS was not causative organism and there was no early onset GBS sepsis. 결론: With the universal prenatal screening using selective culture media, the GBS colonization rate of 11.3% was higher than that performed by previous studies in Korea. Therefore, it is necessary to screen for GBS colonization using selective culture media, and IAP for positive culture women or high risk women is obligatory.