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자외선 조사에 의한 생쥐 피부에서의 일광화상 세포의 정량적 변화
조광열(Gwang Yeol Joh),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1986 大韓皮膚科學會誌 Vol.24 No.1
In this study, a total of 115 ICR male albino haired mice were used and divided into two groups(A & B) for experiment. In group A(65 mice), quantiatation of sunburn cell(SBC) production and its distribution according to the time course after ultraviolet irradiation was measured. In group B(50mice), quantitation of dose-response experiments for SBC production after ultraviolet irradiation was measured. The results were as follows: ]. SBCs were recognized by 2 hours after irradiation. There was a tendency to increase from 2 hours to 24 hours and decrease from then to l week after irradiation, 2. The increase of SBCs in lower epidermis 2 hours io 8 hours after exposure and in upper epidermis 24 hours after irradiation were statistically significant (p<0. 05). SBG number in all layers declined from 36 hours to 1 week after exposure. 3. The linear relationship which observed(y=8.09+0.85x, R=0.87) suggests a dose-response relationship between UVB dose and SBC number.
조광열(Gwang Yeol Joh),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.3
We report a case of solar urticaria being activated by both UVA and visible radiation and positive in passive transfer test by visible light, which was treated with sunlight and UVA radiation. A short course of treatment with sunlight produced no benificial effect. UVA phototherpy produced a rnarked increase in the minirnal urtication dose by UVA but there was no increased tolerance to sun exposure.
조광열(Gwang Yeol Joh),이애영(Ai Young Lee),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.1
It has been generally assumed that eccrine poroma ariees from acroayringium, epidermal sweat duct unit. One of the characteriatics of thie structure is abaence of melanocytes and melanin granules among ite cells. Hmvever, a cornplete abeence of melanocytes and melanin granules in eccrine poroma is not invariable and a few reparts of such an occurrenee were presented, We report a case of eccrine poroma on the area below lateral malleolus af left foot. Microscpically melanin granules, confirmed by the use of Fontana Masson stain, were found in some of the tumor cells.
조광열(Gwang Yeol Joh),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1986 대한피부과학회지 Vol.24 No.1
We report two familial cases of reticulate acropigmentation of kitamura in 20-year-old male and 29-year-old female patients in which reticualte, brownish, slightly depressed pigmentation developed on acral parts of extremities and subsequently extended proximally. Characteristic pits and breaks on palms and soles were noted. Histologic findings revealed epidermal atrophy and enlongation of rete ridges with large amounts of melanin. Electron microscopic findings showed increased melanogenesis in melanocytes and numerous melanosomes and melanosome complex in keratinocytes.
Ota 모반의 임상적 고찰 및 피부 이외의 부위의 색소침착
조광열(Gwang Yeol Joh),은희철(Hee Chul Eun),이유신(Yoo Shin Lee) 대한피부과학회 1986 대한피부과학회지 Vol.24 No.1
This study was undertaken to elucidate extracutaneous hyperpigmentation of nevus of Ota by analyzing the 70 patients who visited Cryosurgery Clinic in Seoul National University Hospital between January 1984 and March 1985 This results were as follows: 1. The age of onset showed two peaks: the first one was at birth or soon after birth; 27 cases(38. 6%) and the second une was between 11 and 17 years; 37 cases (45. 7%). 2 Seventy cases were classified by Taninos method: 15.7% was type I a, 27. l% type I b, 28. 6% type Il, 20. O% type g and 8. 6% type IV 3.Fifty two out of 70 cases who were examined at the department of ophtha1rnology: pigrnentation of sclera was observed in 29 cases(55. 8%.), of conjunctiva in 18 cases(34.6%), of uveal tract in 14 cases(26. 9A), of fundus in 14 cases (26. 9%) and of optic papilla in 2 cases(3. 8%). 4 Fifty two out of 70 cases who were examined at the department of Otorhinolaryngology. pigmentation of tympanum was observed in ]0 cases(23, 8%,), of nasal mucosa in 6 cases(14. 3p,), of oral mucosa in 5 cases(11, 9%), of external auditory canal in 4 cases(9 5%) and of pharynx in 1 case(2. 4%,)
조광열(Gwang Yeol Joh),이애영(Ai Young Lee),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1984 대한피부과학회지 Vol.22 No.6
Becker's nevus or Becker's melanosis is a distinct clinical entity in which epimal thickening may be minimal and hairiness and pigmentation obvious. 1Ne report a case of 14-year-old female suffering from Beckers melanosis with multiple and extensive skin lesions. The electron microscope revealed that the melanocytes were bulky with increased melanogenesis and an increased number of melanosomes was found in the keratinocytes. In addition, a large number of melanosomes were seen individually in the keratinocytes.
조광열(Gwang Yeol Joh),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.3
Solar urticaria is an uncommon disorder characterized by rapid development of urticarial reaction in areas of skin exposed to nonizing electromagnetic radiation. Herber and Baer classified solar urticaria into eight types on the basis of action spectrum and passive or reverse passive transfer ability. We report two cases of type ]g solar urticaria which were activated by visible light and negative in both passive and reverse passive transfer test.
조광열(Gwang Yeol Joh),남종택(Ki Ho Kim),김기호(Jong Taik Nam),김영수(Young Soo Kim),이봉구(Bong Ku Lee) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.6
Nevoid basal cell carcinoma syndrome is inherited as an autcsonal dominant trait with a high degree of penetrane and variable expressivity. The mair features are basal cell carcinoma. jaw cysts, skeletal anornalies, ectopic calcifications and palmoplantar pits. We report varous clinical ma.nifestations in brother and sister, wnich are jaw cyst,, bifid rib, shortened fourth metacarpals, ectopie calcification, palrnoplanar pits and basal cell carcinoma, Microscopically, histologic patterns of basal cell cacinomas are superficial, nodulocystic, keratotic, pigmented, adenoid and follicullar nevoid. Lange numbers of basal cell carcinomas were electrodessicated and curetted under general,nesthesia. (Kor J Dermatol 1992;30(6):951-957)
정규용,조광열,안희창,김기호,김석권 大韓成形外科學會 1994 Archives of Plastic Surgery Vol.21 No.2
We have experienced 4 cases of acral lentigenous melanoma in fingers at Dong-University Hospital for last 4 years. 3 cases occurred on the thumb and 1 case occurred on the index finger. The age of patients was from 6 years old to 62 years old. The Clark level was Ⅰin 1 case, Ⅲ in 3 cases, and the maximal depth of lesion was less than 0.5mm. The patient who had lesion on his index finger was treated with ray amputation and direct closure. 3 patients who had lesion on their right thumbs were treated with wide resection and immediate reconstruction with wrap around free flap. We have followed up the patient for 1 year to 4 years. There were no recurrence and they have used their hands satisfactorily. We report 4 cases of acral lentigenous melanoma developed on their fingers.