요추간 수핵탈출증 환자에 대한 방사선학적 고찰

정흥섭,이기찬,이훈갑,김헌대,주정화 대한신경외과학회 1981 Journal of Korean neurosurgical society Vol.10 No.2

X-ray films of the lumbosacral spine are necessary in the evaluation of all patients who are considered to have lumbar disc disease. Several positive X-ray film findings are of possible significance, and although not in themselves diagnostic, they are compatible with, lumbar disc disease. Among patients treated and diagnosed by surgical operation for lumbar disc herniation from August, 1978 to February, 1981 at Korea University Hospital, 132 cases with their simple X-rays availuable for study were selected. Height of intervertebral disc space (Hurxthal method), spurrings, changes in facet joint, size of spinal canal (Johnes & Thomson method), lumbosacral angle (Ferguson method), congenital defect were studied and measured in simple films. Lumbar disc herniation was most frequent at L4-L5 intervertebral space (65.5%). The incidence of positive radiological findings were 85.6%. 1, Intervertebral disc space narrowing was found in 25%, 59.3% and 50% at L3-4, L4-5 and 2nd L5-S1 level respectively. 2. Peripheral osteophyte formations in the bodies of lumbar vertebrae were found in 44.7%. 3. Narrowing and/or sclerotic changes of facet joint were observed in 31.06%, subluxation in 14.39% and facet tropism in 5.3%. 4. The overall mean size of spinal canal at L4 vertebral level was 1 : 4.325 in male, 1 : 3.898 in female and at L5, 1 : 3.772 in female. Narrowed spinal canal in this series were found in 25.6%. at L4 and 17.2% at L5. 5. The overall mean lumbosacral angle %as 32.4 degree in male and 31.5 degree in female. Spondylolysis was observed in 4.54%. spondylolisthesis in 3.03%, lumbarization in 8.3% and sacralization in 1.51 %.

실험적 뇌경색에 미치는 Insulin, 2-Deoxyglucose 및 Dichloroacetate의 효과에 대한 연구

정흥섭,박윤관,이훈갑,이기찬,주정화 대한신경외과학회 1991 Journal of Korean neurosurgical society Vol.20 No.5

Hyperglycemia has been reported to worsen the tolerance of the brain to ischemia, and it has therefore been recommended that patient undergoing neurosurgical procedures not receive glucose-containing solutions. Since ischemic events lead to increased lactate production and accumulation and hence neruonal damage, the present study was designed to test the effect of insulin-induced hypoglycemia and decreased lactate accumulation by 2-Deoxyglucose and Dichloroacetate on focal cerebral ischemia in rats. Although the pre and post-ischemic blood glucose level of 2-Deoxyglucose group showed a significant increase (p=0.001), and insulim group a significant decrease(p=0.004). The reducing effects on the infarct zone in these three treated groups were found with statistical significance. As compared with control group, the tissue lactate levels of treated groups were decreased in both infarct zone and border zone but these data did not show statistical significance. From these observations, it is suggested that reduction of lactate production and accumulation could be beneficial by affording neuronal protection in ischemic tissues.

근 자외선 발광다이오드 구조의 광학적 특성 향상을 위한 저 결함 GaN 수평성장

정흥섭,홍창희,조형균 한국물리학회 2005 새물리 Vol.51 No.2

Heteroeptaxial lateral overgrowth of low-defect GaN was performed on sapphire substrates by using metal-organitic chemical-vapor depos-ition, and epitaxial layers of near UV-LEDs (ultraviolet light-emitting diodes) were grown on the low-defect GaN. The sapphire substrates were patterned with very thin SiO$_2$ stripes with a thicknesses of 200 - 500 \AA. First, a GaN nuclea-tion layer was grown on the pattern-ed substrate, which was immediately followed by a lateral overgrowth of GaN at a high temperature. The density of screw- and mixed-type threadingdislocations over the entire region of the laterally grown GaN was about 2.5 $\times$ 10$^7$ cm$^{-2}$, and the crystal-lographic tilt was reduced to degree of tilt of conventional GaN grown on flat sapphire substrates. The hotoluminescence intensity of the near UV-LED grown on the low-defect GaN was higher by about 200 \% than that of the near UV-LED grown on conventional GaN. 유기금속 화학기상 증착 (metal-organitic chemical vapor depositin)방법을 이용하여 사파이어 기판 위에 저 결함 GaN의 이종접합 수평성장을시행하고 그 위에 근 자외선 발광 다이오드 (light-emitting diode: LED)에피 층 (epitaxial layers)을 성장하였다. 사파이어 기판 표면은 SiO$_2$ 줄무늬 마스크가 형성되었으며 그 두께는 200 - 500 \AA 이었다. 먼저 줄무늬 마스크가 형성된 기판 표면에 핵 형성 층을 성장한 후, 그 위에 고온 GaN 수평성장이 진행되었다. 고온 수평 성장된 저 결함 GaN 박막에서 나선형과 혼합형 관통전위 (threading dis-location)의 밀도는 전 영역에 걸쳐 약 2.5 $\times$ 10$^7$ cm$^{-2}$ 이었으며 결정학적 기울어짐 현상은 평탄한 사파이어 기판 위에 성장된 GaN 박막 수준으로 낮아졌다. 저 결함 GaN 박막 위에 성정된 근 자외선 LED 에피 층의 photoluminescence 특성은 기존의 GaN 박막 위에 성장된 근 자외선 LED의 발광 세기보다 약 200 \% 증가하였다.

대중국 수출, 국내 재고량 부족 심화

정흥섭 (사)한국포장협회 2004 包裝界 Vol.131 No.-

두개내 발생한 지주막낭종 치험 2예

정흥섭,이훈갑,이기찬,주정화 대한신경외과학회 1979 Journal of Korean neurosurgical society Vol.8 No.1

The intracranial arachnoid cysts are benign lesions in nature which thin walled cysts lying in relation to or enclosed by the subarachnoid space, filled with clear fluid. They may be due to developmental defects of the brain or meninges and secondary to inflammation, vascular occlusion or trauma but etiology of a large percentage is not well understood. In general, locations are near primary fissure and cisterns of the cerebral cortex and cerebellum. The clinical features and courses are unusual. Preoperative diagnosis is unlikely to be made but treatment is followed by good result. We had experienced two cases of intracranial arachnoid cysts which occures in middle cranial fossa, and cerebral hemisphere. Pathologic diagnosis are arachnoid cysts.

실험적 뇌경색에 미치는 Insulin, 2-Deoxyglucose 및 Dichloroacetate의 효과에 대한 연구

정흥섭,박윤관,이훈갑,이기찬,주정화 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.1

Hyperglycemia has been reported to worsen the tolerance of the brain to ischemia, and it has therefore been recommended that patient undergoing neurosurgical procedures not receive glucose-containing solutions. Since ischeruc events lead to increased lactate production and accumulation and hence neuronal damage, the present study was designed to test the effect of insulin-induced hypoglycemia and decreased lactate accumulation by 2-Deoxyglucose and Dichloroacetate on focal cerebral ischemia in rats. Although the pre and post-ischemic blood glucose levels of control group and Dichloroacetate group showed no change, the blood glucose level of 2-Deoxyglucose group showed a significant increase(p=0.001), and insulin group a significant decrease(p=0.004). The reducing effects on the infarct zone in these three treated groups were found with statistical significance. As compared with control group, the tissue lactate levels of treated groups were decreased in both infarct zone and border zone but these data did not show statistical significance. From these observations, it is suggested that reduction of lactate production and accumulation could be beneficial by affording neuronal protection in ischemic tissues.

급성 자발성 척수경막외혈종 1예 보고 : Case Report

정흥섭,주정화,이기찬,이훈갑 대한신경외과학회 1980 Journal of Korean neurosurgical society Vol.9 No.1

We have reported a case of acute spontaneous spinal epidural hematoma in a make patient aged 79-year-old who had suddenly felt a strong pain in the right buttock and lower abdomen. Shortly after he noticed weakness in his legs and two hours later he was completely paraplegic. Operation was undertaken 13 hours after the onset of the illness. A laminectomy was mode from T11 to L1 and a massive epidural hematoma removed mainly from the right posterolateral aspect of the cord.

골판지 포장공업 일선 판매사원은 말한다

정흥섭 한국골판지포장공업협동조합 1999 골板紙包裝ㆍ物流 Vol.6 No.27

요추간 수핵탈출증 환자에 대한 방사선학적 고찰

정흥섭,이기찬 고려대학교 의과대학 1982 고려대 의대 잡지 Vol.19 No.1

X-rays films of the lumbosacral spine are necessary in the evaluation of all patients who are considered to have lumbar disc disease. Several positive X-ray film findings are of possible significance, and although not in themselves diagnostic, they are compatible with lumbar disc disease. Among patients treated and diagnosed by surgical operation for lumbar disc herniation from August, 1978 to February, 1981 at Korea University Hospital, 132cases with their simple lumbar spine X-rays available for study were selected. height of intervertebral disc space, spurrings, changes in facet joint, size of spinal canal, lumbosacral angle, and the congenital defect were studied and measured in simple films. Lumbar disc herniation was most frequent at L4-L5 intervertebral space (65.5%). The incidence of positive radiological findings were 85.6%. 1. Intervertebral disc space narrowing was found in 25%, 59.3% and 50% L3-4, L4-5 and L5-S1 lever respectively. 2. Peripheral osteophyte formations in the bodies of lumbar vertebrae were found in 44.7%. 3. Narrowing and/or sclerotic changes of facet joint were observed in 31.06%, subluxation in 14.39% and facet tropism in 5.3%. 4. The overall mean size of spinal canal at L4 vertebral level was 1:4.33 in male, 1:3.90 in female and at L5, 1:4.06 in male, 1:3.77 in female. (1:3.90) Narrowed spinal canal in this series were found in 25.6%, at L4 and 17.2% at L5. 5. The overall mean lumbosacral angle was 32.4 degree in male and 31.5 degree in female. 6. Spondylolysis was observed in 4.54%, spondylolisthesis in 3.03%, lumbarization in 8.3% and sacralization in 1.51%.

시각유발전위 반응의 임상적 응용

옥광휘,정흥섭,서중근,이훈갑,주정화 대한신경외과학회 1987 Journal of Korean neurosurgical society Vol.16 No.4

Visual evoked potentials were elicited by flash in 29 patients with a variety of cerebral lesions and in 10 normal controls. In 12 patients with focal brain lesions, no wave form could be recorded in one side. Of the remaining 23 sides, the average P₁ latency showed no difference from that of the normal controls. In 17 patients with diffuse brain lesions no wave form could be elicited in 12 sides. Average P₁ latency of remaining 22 sides showed statistically significant difference from that of normal controls. In this study it appears that delayed P₁ latencies are associated with diffuse cerebral lesions rather than with localized lesions.