정형외과와 관련된 다발성 손상 환자에 대한 치료

장의찬 중앙대부설한국의과학연구소 1996 한국의과학 Vol.28 No.3

사고로 인한 소아골절 분석

장의찬,유태열 대한골절학회 2000 대한골절학회지 Vol.13 No.3

Introduction: The purpose of this study was to investigate the characteristics and types of accident caused to pediatric fracture and to concern the prevention of children' s accident. Material and Method: In retrospective study, the pediatric patients, who were visited to our emergency room due to fracture, were classified by age, fracture site, placement of accident, injury mechanism, time and side of injured site which is right or left. Result: Total 441 patients were visited due to fracture from Jan. 1994 to Dec. 1998, frequent fracture site associated to each age group was the elbow joint in 0-4 years and in 5-9 years, and the wrist joint in 10-14 years(P$lt;0.05), and the most frequent accident place was home in 0-4 years, street in 5-9 years and in 10-14 years, and the most frequent mechanism of injury was a fall from height in 0-4 years and slip down in 5-9 years and 10-14 years(P$lt;0.05), and the most frequent time occurring the accident was 7-9 PM in 0-4 years, 4-6 PM in 5-9 years and in 10-14 years. Conclusion In children aged 0-4 years, the accident occurred most frequently during 7-9 PM when child were staying home through fall from height and the common fracture site was elbow joint, and in children aged 5-9 years, the accident occurred most frequently during 4-6 PM through slip down and the common fracture site was elbow joint, and in children aged 10-14 years, the accident occurred most frequently during 4-6 PM through slip down and the common fracture site was wrist joint.

부숙토(腐熟土) 함수율 저감을 위한 유도가열 방식 低전력 高速 건조장치

장의찬,김용주 대한환경공학회 2019 대한환경공학회 학술발표논문집 Vol.2019 No.12

배양된 가토 연골세포에 대한 Recombinant interleukin-1 beta의 작용

장의찬,정상인,전재명,이은우 중앙대학교 의과대학 의과학연구소 1992 中央醫大誌 Vol.17 No.3

Phagocytosis by polymorphonuclear leukocytes of macrophages initiates a burst of oxidative metabolism which is accompanied by the teneration of highly reactive free radicals including superoxide, singlet oxygen and hydroxyl radical. These can decrease the viscosity of the synovial fluid through depolymerization of hyaluronate and also affect cartilage collagen and proteoglycans. Therefor these may exert deleterious effects on the joint structures. In recent years numerous studies have made on interleukin-1, implicating it as a principal mediator of inflammatory responses in the tissue. It has been known that this small polypeptide produced by macrophage lineage cell has numerous important biologic functions. The presence of interleukin-1 in the culture supernatants from rheumatoid arthritis synoviums has been shown to be correlated with the severtity of inflammatory and destructive changes in the joints. In the culture, rheumatoid synovial cells stimulated by interleukin-1 produce large amounts of prostaglandins and collagenase. Chondrocytes sxposed to interleukin-1 also produce and release prostaglandins and metalloproteinases in large quantities. This study was intended to test the hypothesis that recombinant interleukin-1 beta(r II-1β) could stimulate cultured rabbit articular chondrocyte to generate and release superoxide anion that is involved in articular cartilage destruction. The release of superoxide anion was assayed on the basis of SOD inhibitable reduction of fefficytochrome c in the presence of abscence of r IL-1β. To investigate that the cytotoxic effect of r IL-1β on cultured rabbit chondrocyte could be mediated through superoxide anion, the number of cultured chondrocyte was assayed in the presence or abscence of superoxide dismutase. The results are summarized as follows; 1. The time required for cultured rabit articular chondrocytes to from a monolayer in primary culture was approximately 8-10 days. The grown chondrocytes were round and polygonal but through serial subcultures, the chondrocytes became fusiform cell resembling fibroblasts. After fifth subculture a monolayer culture of cultured rabbit articular chondrocytes showed the appearence of dedifferentiated fibroblast-like shape and failed to show metachromasis with Toluidin blue-O stain and Alcian blue stain. 2. rIL-1β significantly enhanced superoxide anion release from cultured chondrocytes(the 2nd passage level). Such increases of superoxide anion releases were observed at a low concentration of this agent, 0.01U/ml and the release reached near maximal level at 0.5U/ml(p<0.01). With rIL-1β at 0.5U/ml. a significant increase in superoxide anion release was detected at 10minutes incubation and the release of superoxide anion began to level off after 15 minutes. 3. It was found that the amount of superoxide anion released from rabbit peritoneal macrophage by rIL-1β was almost same as that of superoxide anion released from cultured rabbit chondrocytes. 4. Through the experiment, cultured chondrocytes treated by rIL-1β promoted superoxide anion release and cytological evidences indicated the rIL-1β treatment of cultured chondrocytes did result in significant retardation of cell growth. However simultaneous addition of superoxide dismutase with rIL-1β(0.01, 0.1unit/ml) ameliorated the inhibitory effect of superoxide anion on chondrocyte growth, implying that the cytotoxic effect of rIL-1β on cultured rabbit chondrocytes was mediated through superoxide anion.

복부 근육 운동에 대하여

장의찬 대한검도학회 1999 대학검도보 Vol.- No.12

건강관리코너 - 인체 중심과 운동

장의찬,Jang, Ui-Chan 한국화재보험협회 2006 防災와 保險 Vol.116 No.-

사과에도 중심(core)이 있고 지구도 지표면과 안으로 중심이 있듯이 인체에도 몸의 중심 부위가 있다. 보통 단전 부위에 무게중심이 있다고 설명을 한다. 단전의 위치에 대해서는 여러 가지 설이 있어 한마디로 정의하기는 어려우나 일반적으로 상단전, 중단전, 하단전으로 분류학 상단전은 뇌 부분, 중단전은 심장에서 명치 부분, 하단전은 배꼽 아래 부분에 있다고 한다. 단전이라고 할 때 약간의 차이는 있지만 아랫배 부근을 가르키며, 기해라고도 한다. 특히 하단전은 모든 경락이 모이는 곳으로서 원기를 저장하는 곳이며 기 흐름의 요체이다. 또한 생명력을 배양하는 곳이자 복식호흡의 기본력이라고 알려져 있다. 그러면 의학적으로는 어떤 것을 신체 중심(core)이라고 이야기 할까?

제 4-5 요추간 추간판 탈출증에 시행된 최소 침습적 두 술식의 비교: 경피적 내시경하 추간판 절제술과 통형 견인기하 추간판 절제술

장의찬,강기서,김재윤,양재준,고영봉,송광섭,김기성 대한척추외과학회 2009 대한척추외과학회지 Vol.16 No.3

Study Design: A prospective, non-randomized study Objectives: To evaluate the early clinical results of percutaneous endoscopic lumbar discectomy (PELD) and microdiscectomy (MD) using a tubular retractor. Summary of the Literature Review: There are few reports comparing the clinical results of different minimal invasive surgical procedures for disc herniation. Materials and Methods: Out of 41 patients who underwent a discectomy at the L4-5 level, 16 patients (Group Ⅰ) underwent PELD and 25 patients (Group Ⅱ) underwent MD. The surgical techniques were based on the patient’s selection. The characteristics of the operation(operation time, time for C-arm, amount of removed disc) were compared with the clinical outcomes by evaluating the SLR (straight leg raising test), leg VAS (visual analogue scale), ODI (Oswestry Disability Index), hospital day, changes in disc height. Results: Group I showed a larger amount of disc removed and exposure time for the C-arm than group Ⅱ (p<0.05). However, the hospital day was shorter in group I than in group Ⅱ (p<0.05). There were no differences in the leg VAS, ODI, the change in disc height and surgery time between the two groups at the last follow up. One case in group I had a neuropraxia of the L5 root that had recovered fully at postoperative 3months. In group Ⅱ, there was one case of a postoperative hematoma and 2 cases of a dural tear. Conclusion: Although the early clinical outcomes were similar in both groups, group Ⅰ showed a larger amount of disc removed and more exposure time to radiation but a shorter hospital stay. 연구계획: 무작위 하지 않은 전향적 연구 연구목적: 경피적 내시경을 이용한 추간판 제거술과 현미경하 통형 견인기를 이용한 추간판 제거술의 초기 임상적 결과를 비교하고자 한다. 대상 및 방법: 제 4-5 요추간 추간판 탈출증으로 본원에서 내시경 추간판 절제술을 받은 환자 16명(1군, 평균 추시기 간 15(12~19)개월), 견인기를 이용한 현미경하 추간판 절제술을 받은 환자 25명(2군, 평균 추시기간 14(12~18)개월) 을 대상으로 하였다. 수술방법의 결정은 환자 본인이 선택하도록 하였으며 수술 방법의 특징(수술 시간, 수술 중 방 사선 노출시간, 제거된 추간판의 양)과 임상적 평가(하지직거상 검사, VAS, ODI, 입원기간, 추간판 간격의 변화)를 시행하였다. 결과: 제거된 추간판의 양(1군: 1.9(0.8~3.1)cc/2군: 1.1(0.5~2)cc) 및 방사선 증폭장치의 사용시간(1군: 41(17~120)초/2 군: 15(6~41)초)은 1군에서 많았으나 입원 기간은 유의하게(p<0.05) 짧았다(1군: 4(2~8)일/2군: 8(4~14)일). 임상적 평 가 및 수술 시간에서는 양 군 간 의미 있는 차이는 없었다(p>0.05). 수술 후 합병증으로 1군에서는 요추 5번 신경의 일 시적 신경손상(3개월간 근력약화) 1례, 2군에서는 수술 후 혈종 1례, 경막 파열 2례의 합병증이 발생하였다. 결론: 1군에서 의미 있게 입원기간이 적었지만 방사선 노출시간 및 제거된 추간판의 양은 많았다. 제거된 추간판의 양이 1군에서 많았던 점은 필연적인 정상 추간판 조직의 간접적 감압에 의한 것으로 사료되며 두 군간의 초기 임상 적 결과에는 유의한 차이를 보이지 않았다.

키토산 구슬을 이용한 가토 연골세포의배양

장의찬,김경환,저호중,이기현,정상인,손태일 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

단순 방사선 사진 상 Wintopo. 프로그램을 이용한 척추 방출성 골절의 진단

장의찬,정호중,박철경 대한정형외과학회 2003 대한정형외과학회지 Vol.38 No.4

검도와 척추

장의찬 대한검도학회 1998 대학검도보 Vol.- No.11