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Ice plant (Mesembryanthemum crystallinum) 추출물의 생리 활성
이상률(Sang Yull Lee),최현덕(Hyeun Deok Choi),유선녕(Sun Nyoung Yu),김상헌(Sang Hun Kim),박슬기(Seul Ki Park),안순철(Soon Cheol Ahn) 한국생명과학회 2015 생명과학회지 Vol.25 No.6
본 연구는 ice plant (Mesembryanthemum crystallinum)의 생리활성을 분석하여 기능성 식품으로서의 가능성을 조사하였다. Ice plant는 아프리카와 서유럽, 북미, 남미 그리고 호주에서 서식하는 다육식물로 항당뇨, 항산화, 지질 대사 활성에 효능이 있다고 알려져 있다. Ice plant를 methanol (MCM), ethanol (MCE), 열수(MCHW), 열수추출 후 methanol (MCHM)로 추출하여, mushroom tyrosinase, pancreatic lipase, DPPH free radical 소거 활성, NO 생성, α-glucosidase에 대한 저해 활성을 측정 하였다. MCM, MCE, MCHW, MCHM 추출물의 추출 수율은 0.37%, 0.33%, 0.5%, 0.07%로 나타났다. MCHW 추출물은 DPPH free radical 소거능에 높은 효과를 보였고, MCM, MCE 추출물은 lipase 저해 활성, α-glucosidase 저해 활성, NO 생성 저해활성을 보였다. 그러나 mushroom tyrosinase 저해 활성은 모든 추출물에서 매우 낮았다. 이러한 결과를 통해 ice plant는 항산화 물질로서 비만, 당뇨, 염증 치료용 기능성 식품으로서의 가능성이 매우 높음을 확인할 수 있었다. This study analyzed the physiological quality of Mesembryanthemum crystallinum (ice plant) extract. M. crystallinum is a succulent plant found in Africa, southern Europe, North America, South America, and Australia. It has known antidiabetic, antioxidant, and activation of lipid metabolism effects. Extracts from M. crystallinum were prepared with methanol (MCM), ethanol (MCE), hot water (MCHW), and methanol after hot water (MCHM) extractions. The yields of MCM, MCE, MCHW, and MCHM were 0.37, 0.33, 0.50, and 0.07%, respectively. To determine the biological activities of the extracts, mushroom tyrosinase, pancreatic lipase, 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging, nitric oxide (NO) production, and α-glucosidase assays were conducted. The DPPH radical scavenging activity of the MCHW extract was 62.9% at a concentration of 400 μg/ml, which was the highest of all the extracts. The MCM extract showed the highest inhibition activity of α-glucosidase and NO production (56.6 and 57.2%, respectively). The pancreatic lipase inhibition of the MCE extract was similar to that of the MCM extract, with significant inhibition of 90%. The mushroom tyrosinase inhibition of all the extracts was very low (approximately 30%). These results suggest that extracts from M. crystallinum have antioxidant, anti-inflammatory, antiobesity, and antidiabetic activities. Thus, it may have potential as a functional food product and therapeutic potential as an antidiabetic or antiobesity agent.
자이로 효과의 피칭 모션을 고려한 한 바퀴 로봇의 모델 기반 롤링 모션 제어
이상덕(Sang-Deok Lee),정슬(Seul Jung) 대한전기학회 2016 전기학회논문지 Vol.65 No.2
In general, a yawing motion concept is used for the lateral control of one wheel robot where the gimbal system is located horizontally. In this paper, another concept of the vertically located gimbal system is presented for the same purpose. Although the vertical concept undergoes an instability more easily than the horizontal one, the pitching motion of the gyroscopic effect is considered. Firstly, the trade-off relation between two balancing concepts are investigated by comparing the gyroscopic mechanism. Secondly, the dynamic model for the problem of the proposed concept is derived using the oscillatory inverted stick model. Thirdly, the stability of the model is analyzed using the phase trajectory method. Finally, the control performance of the system by a vibration controller is simulated.