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개의 장문합수술에 있어 봉합 문합술과 Stapler 문합술의 비교
박대식,구자민,성용증,이희천,장홍희,이효종,연성찬 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.4
The effectivenes of a synthetic solution of sodium carboxymethylcellulose (SCMC) and dextran in theprevention of adhesion formation following intestinal anastomosis of intestine in dogs was elucidated and compared withInterceed. Following induction of adhesion on jejunum of dogs by resection and intestinal anastomosis, the dogs wereinfused with a synthetic solution of 1% SCMC and 10% dextran in saline in the abdominal cavity at the dose of 5 ml/kg of body weight or treated with Interced membrane. Fourteen days after operation, all the dogs showed adhesionof anastomotic sites to surrounding tissues. The average score of adhesion was 0.50, 0.60 and 0.80 in the dogs infusedwith the synthetic solution, Interceed membrane and saline solution, respectively. The synthetic solution showed betterresult of adhesion prevention than Interceed or saline solution. No significant change of body weight, vital signs,hematological values and side effects after operation was found in each group. Therefore, a synthetic solution whichis combined with 1% SCMC and 10% dextran in saline can be effectively used for the prevention of adhesion formationcomparable to Interceed membrane following intestinal anastomosis in the dogs.
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Butorphanol의 투여가 장문합술 후 개의 행동에 미치는 영향
구자민,연성찬,이희천,장홍희,성용증,이효종 한국임상수의학회 2005 한국임상수의학회지 Vol.22 No.1
This study was performed to investigate non-invasive behavioral pain assessment of dogs after surgery, and the analgesic effects of butorphanol after intestinal anastomosis in dogs. In this study, five dogs in the Control Group were anesthetized, but did not undergo surgery. Five dogs in the Analgesic Group were undergone intestinal anastomosis and treated with butorphanol. Five dogs in the Non-analgesic Group were also undergone intestinal anastomosis without analgesic treatment. The dogs in the Analgesic Group received butorphanol (0.4mg/kg, IM) before and immediately after operation, while dogs in Control and Non-analgesic Groups received isovolumetric doses of sterile saline. The behavior of dogs were videotaped for 400mins after anesthesia, during which time a researcher interacted with the dog once per each 80 mins. At each interaction, the researcher recorded behavioral pain score, using University of Melbourne Pain Scale. Interactive and non-interactive behaviors were observed and quantitated by a single observer using focal continuous sampling method. Vocalizations were obtained during 400mins after anesthesia, and duration of call, intensity, pitch, 1-4 Formant were analyzed. Surgery affected an increasing of pain score. During interactions with researcher, greeting behaviors were decreased after surgery. Differences between Analgesic group given analgesic or that given a placebo drug were readily understood using quantitative behavioral measurements and vocalization. Significant difference between Analgesic group given butorphanol or that the given placebo drug was apparent(p<0.05).
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