http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
후천성면역결핍증후군 환자에서 발생한 Rifabutin에 의한 포도막염 1예
박용출,이지웅,신재필,김시열 대한안과학회 2009 대한안과학회지 Vol.50 No.6
Purpose: To describe a case of symptomatic rifabutin-related uveitis with hypopyon and vitreous opacity in apatient with acquired immunodeficiency syndrome infected with Mycobacterium tuberculosis. Case summary: A 33-year-old male patient with acquired immunodeficiency syndrome was referred to our clinic for abruptly decreased vision in his right eye. Multi-drug therapy with rifabutin was administered for 5 weeks to treat tuberculosis enteritis and pulmonary tuberculosis. Visual acuity of the right eye was hand motion and hypopyon as well as vitreous opacity was found in ocular examinations. Other serologic tests, anterior chamber paracentesis and lumbar puncture test were normal. Rifabutin was immediately stopped and topical steroid and cycloplegics were administered, which resulted in resolution of the hypopyon, vitreous opacity and visual acuity. Four weeks after the initial episode, rifabutin was restarted to treat the pulmonary tuberculosis and rifabutin-related uveitis relapsed in the opposite eye. Conclusions: Rifabutin-related uveitis should be considered in cases of uveitis in immunosuppressive patients, especially in acquired immunodeficiency syndrome patients. Underlying disease and medication history should be carefully assessed. 목적: 결핵균(Mycobacterium tuberculosis)에 감염된 후천성면역결핍증후군 환자에서 전방 축농과 유리체 염증을 동반한 rifabutin에 의한 포도막염 1예를 경험하였기에 이를 보고하고자 한다. 증례요약: 33세 남자인 후천성면역결핍증후군 환자가 우안에 전방 축농과 유리체 염증을 동반한 포도막염 소견을 보였다. 환자는 항바 이러스 병용요법 및 fluconazole치료를 받고 있었고, 결핵성장염, 폐결핵이 합병되어 rifabutin을 포함한 다제약물요법 치료를 받고 있었다. 혈청학적 검사, 전방천자검사 및 뇌척수액검사상 다른 감염소견은 보이지 않았다. Rifabutin에 의한 포도막염으로 진단하고 rifabutin과 fluconazole을 중단하고, 스테로이드 및 조절마비제를 점안하였다. 점안치료 후 전방축농 및 유리체염증은 급격히 호전되 었고 정상 시력으로 회복되었다. Rifabutin 중단 후 폐결핵 치료를 위해 rifabutin을 다시 복용하였고, 복용 1달 후 좌안에 전방 축농과 유리체염증을 동반한 포도막염이 재발하였다. 결론: 면역억제환자, 특히 후천성면역결핍증후군 환자에서 발생할 수 있는 포도막염의 원인 중 rifabutin에 의한 포도막염을 유의하고 기저질환 및 약물 복용력을 확인해야 한다.
바람장 및 Fingerprint를 이용한 악취추적기법 활용가능성 평가
나경호,박용출,장영기 한국대기환경학회 2007 한국대기환경학회지 Vol.23 No.1
This study was carried out to evaluate the applicability of the odor source tracking using wind field and fingerprint as a solution tool. First of all, CALMET and HYSPLIT modeling system, and database of odor discharge companies were utilized to track odor from industrial complexes. Secondly, industrial odor fingerprint was made by listing on the 19 domestic industries, and compared with foreign data to assess the representative, and thus the similarity was 86.7%. On the modeling experiment, Sihwa industrial complex did not show any difference because the matching rates of day and night were 49.5% and 50.0%, respectively. However, the Banwol and Sihwa industrial complexes did show some differences due to odor facility density. Separately, in this study, odor samples were obtained from 10 odor discharging companies, located in the Sihwa and Banwol industrial complexes, They were compared with the results of odor tracking modeling. The matched companies were 4 of 10 by three cases of tracking, while the fingerprint and industry of odor monitoring networks and companies matched each other. Therefore, this study confirmed the approach applicability of source tracking system using the fingerprint.