탈모증 환자의 한의학적 임상 유형에 대한 연구

이태후,문정배,정지행,임강현,김희택,Lee, Tae-Hoo,Moon, Jung-Bae,Jeong, Jee- Haeng,Leem, Kang-Hyun,Kim, Hee-Taek 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.3

Objectives : This study was planed to evaluate clinical status of the alopecia patients who had visited Korean medicine clinic. And the result from this study would provide a standard in Korean medical diagnostic and classification method of alopecia. Methods : Clinical records of 183 patients with alopecia seen from January 2004 to April 2005 at Korean medical clinic was examined. They were classified into 4 different types according to chief complains besides alopecia by 2 Korean medical doctors. Results and conclusions : We made clinical analysis of patients of alopecia from January 2004 to April 2005. Among the alopecia patients who visit Korean medical clinic, people age between 20 and 30 had high ratio. The duration from the recognition of initial hair loss to the time of the first visit to the Korean medical clinic was less than 12 months in 20.8%(38/138), and less than 60 months in 72.2% (132/183). The condition of alopecia was more worse than other alopecia patients who visit the west medical clinic. Also the ratio with increased temperature of face or scalp is chief complaint except alopecia in alopecia patients was high in men and the ratio with dysfunction of digestive system or chronic weakness was high in women. Among the incidence of alopecia, the androgenic alopecia was most in number; 43.7%(80/183) and the sex distribution showed 83 men and 100 women.

방진복착의자의 탈모현황 및 탈모원인에 관한 연구 : 20-30대 직장인을 중심으로

유은희 대한피부미용학회 2015 대한피부미용학회지 Vol.13 No.5

Alopecia negatively effects on normal social life and human relationship in modern society which focuses on physical appearance. This study understands actual condition of alopecia workers who are 20-30years old and exposed to particular environment wearing dust-free garment. It finds out the effect of wearing the dust-free garment on alopecia. Accordingly 80 workers, the garment wearers were subjected in question and diagnosis investigation. As a result, 61.3% of the garment wearer was in hair loss. The primary reason was wearing of dust free garment. Early stage of alopecia was 81.6% in their twenties. 46.9% showed early stage of the alopecia after 1 year of wearing the dust-free garment. 26.5% showed alopecia after 3 years. It reflects that the alopecia was induced within 3 years after wearing the garment. The cause of alopecia was inquired into change of body temperature due to wearing of the dust-free garment. 62.3% of alopecia patient had high temperature and 61.5% had highest humidity on their parietal region. The fact that temperature of parietal region will effect on hair loss already has proven case and elevation of humidity effects on alopecia since it provides good environment to become sensitive scalp condition and proliferate bacteria. The researchers could confirm that stress from change of body temperature (in other words, elevation of temperature and humidity of parietal region) and closed construction manifested major cause of alopecia. There is no specific mechanism of alopecia since it is too complicated and various. The researchers see that abnormality of endocrine system and external environmental factors worked together. Therefore, it is hard to say that wearing the dust-free garment is the only reason of alopecia, but it gives significant effects on it. From now on we need constant study to improve prevention of alopecia for workers in important industry.

방진복착의 근무자와 일반직장인의 탈모빈도와 탈모초발시기 비교연구

유은희 대한피부미용학회 2015 대한피부미용학회지 Vol.13 No.4

This study aimed to specifically verify increasing tendency of alopecia among young generation and influencing relationship between working environment and alopecia. As a result the frequency of alopecia amongst workers, who are wearing dust-free garment in clean room environments was 61.3% while the general population was 51.3% so the workers in clean room environments showed 10% higher result. Both of the workers in clean room environments and the general workers picked stress as a main reason of alopecia. However, the two groups showed different alopecia causes since the workers in clean room environments chose stress as the prior reason and wearing dust free garment as second reason while the general workers chose genetic factor as the prior reason and stress as the second reason. The initiative stage of alopecia amongst workers in clean room environments was eminently faster than the general workers since 81.6% of the workers in clean room environment and 53.6% of the general workers in twenties appeared initiative stage of alopecia. Form of alopecia of the workers in the clean room environment was comparatively even on parietal region (calvaria) while the general workers had M-shaped alopecia which is a typical genetic alopecia form. The point of the study is that wearing of dust-free garment can advance alopecia stage and act as an alopecia cause among twenties to thirties who work in the clean room environment. In the view of company, therefore, effort and improvement are raised to reduce the stress of wearing dust free garment and especially to get rid of factors that disturb cutaneous respiration.

대학병원 피부과 외래에 내원한 안드로겐 및 원형탈모증 환자에서의 대표적 Trichoscopic Finding에 대한 고찰

임재윤 ( Jae Yun Lim ),민준홍 ( Joon Hong Min ),최영준 ( Young-jun Choi ),남재희 ( Jae Hui Nam ),이가영 ( Ga-young Lee ),김원석 ( Won-serk Kim ),정호주 ( Ho Joo Jung ) 대한피부과학회 2016 大韓皮膚科學會誌 Vol.54 No.9

Background: By magnifying the scalp and structure of hair, trichoscopy enables easy differentiation among various hair loss diseases. Objective: To measure the frequency of representative trichoscopic findings in outpatients with androgenetic alopecia and alopecia areata and the frequency of various trichoscopic findings depending on the disease severity of androgenetic alopecia. Methods: This cross-sectional study included 87 patients with androgenetic alopecia (n=57) and alopecia areata (n=30) treated over a year (2014∼2015). Three dermatologists assessed the trichoscopic findings (hair shaft, hair follicle opening, and perifollicular epidermis) in these patients. Results: Vellus hair was observed in 21 of the 30 patients (70%) with alopecia areata and 20 of the 57 patients (35%) with androgenetic alopecia. Among the patients with androgenetic alopecia, as the disease severity increased, the portion of patients with vellus hair, thickness heterogeneity, and honeycomb pigmentation also increased (p<0.05). Conclusion: Trichoscopy is very useful for the diagnosis of androgenetic alopecia and alopecia areata. Additionally, the severity of androgenetic alopecia can be assessed using trichoscopy. (Korean J Dermatol 2016;54(9):699∼705)

탈모증환자 1505명의 임상적 연구

이준상(Jun Sang Lee),임철완(Chull Wan Ihm) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.10

Background:In the patients complaining of alopecia or hair thinning, many different disease entities are included. Although there have been many clinical studies on each individual disease of them, few reports dealing with all of the alopecia patients in a dermatologic clinic are found. Objective:We attempted to reveal the collective clinical aspects of all of different diseases resulting in loss of hairs in a dermatologic clinic. Method:Clinical records of 1505 patients with various alopecia seen from March 1978 to July 1998 at the department of Dermatology, Chonbuk National University Medical School were analyzed for their diagnosis, age, sex, and annual distribution in all dermatoses. Among them, 1252 cases were further studied for their subtypes, causes, result of treatments and other details. Results:1. The incidence of total alopecia patients among the total new patients during the period was 2.9%(1505/51140), 1.24% in average during the 1980s and 4.7% during the 1990s. 2. The incidence of different alopecia was as follows: alopecia areata; 55.0%(827/1505), androgenetic alopecia; 26.1%(392/1505), telogen effluvium; 7.0%(106/1505), trichotillomania; 3.6%(54/1505), accidental alopecia; 1.9%(28/1505), seborrheic alopecia; 1.2%(18/1505), and nutritional alopecia: 0.9%(14/1505). 3. The sex distribution showed 761 men and 744 women. The age distribution showed a peak incidence in the third decade(37.4%, 563/1252). 4. The duration from the recognition of initial hair loss to the time of the first visit to the hospital was less than 3 months in 46.4%(581/1252), and less than 6 months in 60%. 5. The subtypes of 686 cases of alopecia areata consist of 549(80%) cases of common type, 77(11.3%) cases of alopecia totalis, and 60(8.7%) cases of alopecia universalis. 6. The relapse rate after treatment in alopecia areata was 29.4%. In 7.4% there was no response to the treatment. 7. Of the 160 male androgenetic alopecia patients Hamilton's type II and III were most common (92.5%). Of the 60 female androgenetic alopecia patients Ludwig's type I was most common(58.5%) 8. The presumed causes of telogen effluvium was as follow: delivery(23.1%), febrile illness (22.0%), traction(8.8%), drug administration(6.6%), crash diet(5.5%). 9. In trichotillomania, the male to female ratio was similar. 70% of the patients belonged to the 1-20 year age group. (Korean J Dermatol 2000;38(10):1348~1357)10. Accidental alopecia or the alopecia caused by accidental trauma occurred most commonly in women(79%, 22/28). 11. All patients of nutritional alopecia or the alopecia due to diminished diameter of the hair(14cases) and traction alopecia(6cases) were women. Conclusion : We made clinical analysis of all of the patients complaining of hair loss by any causes during the past 20 years from March 1978 to July 1998.

연구논문 : 혈액형에 따른 성격분류 및 탈모 민감도

이재숙 ( Jae Suk Lee ) 한국미용학회 2007 한국미용학회지 Vol.13 No.3

Alopecia is now increasing belong with the social complexity and cultural development. People who troubled about alopecia are over six million, alopecia related shampoo market is about 15-20 billion won, alopecia related market is more about one trillion won and the products are over 1,600 kinds. Former days, the primary factor of alopecia was genetic factor, but nowadays as the social complexity increased, stress ia the primary factor of alopecia with others such as genetic factors and irregular dietary life. This study tries to understand interrelationship between inclination of alopecia and blood type by using typical character of blood type statistically, and tries to give psychological satisfaction, close intimacy to the customers knowing their statistic character belonging blood type. Finally, trying to give a material for the better customer oriented service, successful customer management. 1. 865 male to 469 female among total 1334 alopecian, the male alopecia was excessively numerous. 2. Classifying in age, 30 > 20 > 40 > 50 > 60 > 10 in order, 20-30 age alopecia was more than 40-50 age alopecia. 3. Classifying in heredity, none > father > paternal side > brother > mother > maternal side in order. 4. Classifying by blood type, A > B > O > AB in order statistically. 5. Classifying by alopecia type, male alopecia M > M+O > O > C in order, M was most numerous and then M+O, O, C followed in order.

A clinical study of patients with alopecia during 8 years

( Hyun Ok Son ),( Sin Wook Chun ),( Suk Young Lee ),( Jong Baik Kim ),( Byung In Ro ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

Background: Alopecia is a loss of hair from scalp or body. Alopecia has an effect on quality of life psychosocially and cosmetically. Objectives: To evaluate the prevalence of patients with alopecia including androgenic alopecia (AGA), alopecia areata(AA; AT, AU included) and other alopecia. Methods: We collected retrospective data from the medical records with 3,045 out-patients who were diagnosed as alopecia in the Alopecia Clinic, Department of Dermatology, Myongji Hospital during 8 years from March, 2007 to February, 2015. Results: The incidence of alopecia was as follows: AGA (67.7%, n=2,060), AA(28.0%, n=853), telogen effluvium(1.8%, n=56) and others(2.5%, n=76: woolly hair, trichotillomania, cicatricial, traction alopecia). The sex distribution showed 1593 men (52.3%) and 1452 women (47.7%). The age distribution showed a peak incidence in the 3rd to 4th decade (48.4%, n=1,475). Of the 1,198 male pattern hair loss (MPHL) patients,Norwood Hamilton type IIIv was the most common(19.5%). Of the 862 female pattern hairloss(FPHL) patients, Ludwig’s type I was the most common(65.6%). Conclusion: This study supports the fact that the number of patients with early-onset alopecia is increasing recently in Korea.

A Clinical Study of Androgenetic Alopecia (3)

(Joo Hyun Shim),(Sung Wook Ro),(Byung In Ro) 대한피부과학회 2002 Annals of Dermatology Vol.14 No.1

N/A Background: Androgenetic alopecia is considered to be a genetically determined disorder influenced by age and androgen. The proportion of patients with androgenetic alopecia among the total number of patients with alopecia seems to be gradually increasing. Objective: The purpose of this study is to evaluate the family history,clinical and endocrine status of the patients with androgenetic alopecia. Method :1113 patients with androgenetic alopecia who had visited the Department of Dermatology, Yongsan Hospital, College of Medicine,Chung-Ang University during the 3 years (1995.1-1998. 12) have been examined. Results: The results are summarized as follows 1) The incidence of androgenetic alopecia among the total number of alopecia patients was 64.5%, showing recent increment. 2) There were 855 male and 258 female patients being most prevalent in the third decade in both sexes and the patients younger than 30 years old with premature androgenetic alopecia,made up 70.3% of the male patients and 48.8%of the female patients with androgenetic alopecia. 3) While Norwood`s type Iia was the most common and following type II,III vertex,and IV in the male AGA, Ludwig`s type II was the most common in female AGA 4) There was a family history of baldness in 53.5%of first degree relatives in male patients and 51.6%in female patients. 5)Associated diseases were observed in 565(66.8%)of the male patients and 219 (84.8%)of the female patients:diseases associated with androgen such as seborrheic dermatitis and acne vulgaris occupied 39.1%. Conclusion :Based on our findings, those who want to treat androgenetic alopecia at the earlier ages are gradually increasing and it seems to be reasonable to believe that the age, genetic factors, localized effects of androgens on the scalp and the density and/or functional activity of androgen receptors may influence the pathogenesis of androgenetic alopecia. (Ann Dermatol 14(1)11-17,2002).

Clinical and histopathological characteristics of linear alopecia of the scalp in Korea: a single centre experience

( Hyang-suk Ryu ),( Tae-wook Kim ),( Hyun-joo Lee ),( Sung-min Park ),( Hyunju Jin ),( Woo-haing Shim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: A distinctive clinical pattern of alopecia is very important for the differential diagnosis among various alopecia. However, dermatologists may have difficulty making correct diagnosis when alopecia occurred in a linear pattern because their clinical presentation might be extremely rare. Objectives: To identify the clinical and histopathological characteristics of linear alopecia of the scalp in Korean patients Methods: This retrospective study included patients with linear alopecia of the scalp presenting at the Pusan National University Hospital (Busan and Yangsan) during a 15-year period (2002-2017). In all the patients, biopsies were performed and final diagnosis was made based on clinical and histopathologic findings. We reviewed medical records, clinical photos, and histopathological slides. Results: Twenty-one patients with linear alopecia of the scalp were included in this study. The most common dermatoses was En Coup de Sabre (7/21, 33.3%), followed by alopecia areata (5/21, 23.8%), lupus erythematosus (2/21, 9.5%), pseudopelade of Brocq (2/21, 9.5%), non-specific scarring alopecia (2/21, 9.5%), triangular alopecia (1/21, 4.8%), trichotillomania (1/21, 4.8%), and traction alopecia (1/21, 4.8%). Conclusion: The result of this study could be helpful for dermatologits when encounting linear alopecia of the scalp.

여성의 두피 및 모발관리형태가 탈모에 미치는 영향

모정희(Jeong Hee Mo),송미라(Mi Ra Song) 한국인체미용예술학회 2010 한국인체미용예술학회지 Vol.11 No.3

This study investigated the influence of hair properties, food against alopecia, scalp and hair management types on alopecia to present a healthy scalp and hair management program. For the purpose, this study interviewed 353 women living in Gwangju and adjacent areas using a questionnaire and the data collected were analysed through a descriptive statistical analysis and a multi-regression analysis with uses of SPSS WIN 11.0. The results are presented as follows: First, as a result of analysing difference in alopecia according to scalp and hair management types, it was discovered that there was a difference in presence of alopecia according to the mean frequency of weekly shampooing (t value =-2,474, p<0.01) and the frequency of hair style change (t value = 2,568, p<0.01). Second, when this study analysed the causal effect of hair properties, food against alopecia, scalp and hair management types on alopecia, it was discovered that the more food containing protein, the lower possibility of alopecia. For properties of hair, the more dandruff, oil, and gray hair the subjects had, the higher rate of alopecia they had. However, the more volume of hair, the lower influence on alopecia. Scalp and hair management types were not related with alopecia. Therefore, it was demonstrated that protein processed food such as milk and Tofu prevents alopecia as it is good for scalp and hair. In conclusion, in order to maintain healthy scalp and hair and prevent alopecia, scalp and hair management status should be exactly identified with practice of right hair management and diet.