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Studies on Purification of 1,3-propanediol by Molecular Distillation
Zhe Wang,Zhe Wu,Tianwei Tan 한국생물공학회 2013 Biotechnology and Bioprocess Engineering Vol.18 No.4
The separation of 1,3-propanediol using molecular distillation has been studied. The effects of operating temperature and feed flow rate through a sequential distillation strategy were investigated. The optimal experimental temperature was at 70oC for separating 1,3-propanediol and the by-product 2,3-butanediol. Meanwhile, the volume flow rate was 10 mL/min. As a result, the recovery of 1,3-propanediol and 2,3-butanediol were 87.6 and 87.5%,respectively. Furthermore, the integrated separation characteristic of 1,3-propanediol was evaluated through macrolevel and micro-level models. The separation factors of 1,3-propanediol versus 2,3-butanediol and glycerol were 0.11 and 1.07, respectively, affirming that the separation of 1,3-propanediol by molecular distillation was feasible.
A TEL decision method of process parameters for smart energy efficient manufacturing
Wei Zhe,Feng Yixiong,Hong Zhaoxi,Tan Jianrong 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.8
By constructing a Smart energy efficient manufacturing (SEEM) process grey model, craft parameter optimization is transformed into the process of multi-attribute decision making. Using fuzzy set theory to deal with uncertainty and inaccuracy fuzzy knowledge of SEEM assessment experts, a directly effect incidence matrix and a comprehensive effect matrix of SEEM process are put forward to be indexed by Trial and evaluation laboratory (TEL). The central degree and causal degree of each evaluation index are obtained, and then the relevance is analyzed between SEEM process evaluation indicators and weighted according to impact degrees. At the premise of maximizing of population benefits and minimizing of individual regret, the SEEM process parameters are determined by TEL-VIKOR theory. To obtain SEEM process parameters or compromise process parameters, a decision maker's subjective preference, and establishing control priorities of best SEEM process parameters are set. Finally, SEEM process parameters making decision example from discharge manufacturing process are applied to verify the proposed method.
Fenghui Han,Zhe Wang,Yijun Mao,Yiyun Zhang,Jiajian Tan 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.1
Multi-hole probe (MHP), as a classical measuring instrument, continues to play an important role in the pressure and velocity measurements for industrial applications by virtue of its robust and reliable performance as well as the simple structure and low cost. But the flow directionality limitations and the low efficiency of traditional operations become obstacles to the large-scale measurements of MHPs. In this paper, an improved operating method is adopted for conventional MHPs to extend their measuring range of incidence angles, and a corresponding auto-measuring system has been developed to realize automatic calibration and measurement of MHPs for industrial large-scale flow measurements. Measurement uncertainties of the system have been experimentally analyzed, verifying a good accuracy: errors of 0.36° in pitch angle, 0.40° in yaw angle and 0.83% in velocity magnitude (95% CI). Furthermore, this auto-measuring system has been applied in the large-scale measurements on different radial inlets for industrial centrifugal compressors, which provide valuable flow information that was not previously available for industrial productions and assist with the improvement study. Analysis and applications in this paper prove that the developed system not only reduces the flow directionality limitations of conventional MHPs, but also significantly improves the experimental efficiency and the control-precision of the probe, achieves a good repeatability and ensures the reliability of the experimental data, which satisfies the requirements of large-scale measurements in industrial applications. Meanwhile, the portability of the system makes it more convenient and flexible to be applied in various industrial productions.
Mechanical behavior of rock-coal-rock specimens with different coal thicknesses
Guo, Wei-Yao,Tan, Yun-Liang,Yu, Feng-Hai,Zhao, Tong-Bin,Hu, Shan-Chao,Huang, Dong-Mei,Qin, Zhe Techno-Press 2018 Geomechanics & engineering Vol.15 No.4
To explore the influence of coal thickness on the mechanical behavior and the failure characteristics of rock-coal-rock (RCR) mass, the experimental investigation of uniaxial compressive tests was conducted first and then a systematic numerical simulation by particle flow code (PFC2D) was performed to deeply analyze the failure mechanical behavior of RCR specimens with different coal thicknesses in conventional compression tests. The overall elastic modulus and peak stress of RCR specimens lie between the rock and the coal. Inter-particle properties were calibrated to match the physical sample strength and the stiffness response. Numerical simulation results show that the deformation and strength behaviors of RCR specimens depend not only on the coal thickness, but also on the confining pressure. Under low confining pressures, the overall failure mechanism of RCR specimen is the serious damage of coal section when the coal thickness is smaller than 30 mm, but it is shear failure of coal section when the coal thickness is larger than 30 mm. Whereas under high confining pressures, obvious shear bands exist in both the coal section and the rock section when the coal thickness is larger than 30 mm, but when the coal thickness is smaller than 30mm, the failure mechanism is serious damage of coal section and shear failure of rock section.
Mahadi Ida Arinah,Tan Jih Huei,Teh Jin Zhe,Mohamad Yuzaidi,Rizal Imran Alwi 대한외상학회 2023 大韓外傷學會誌 Vol.36 No.3
Torso stab injuries near the cardiac box may present unique challenges due to difficulties in hemorrhage control. For a stab injury to the heart, the repair is straightforwardly performed via median sternotomy. In contrast, injuries to the inferior vena cava are challenging to repair, especially when they are close to the diaphragm, and the bleeding can be torrential. Herein, we describe a case of a self-inflicted stab wound within the "cardiac box." The trajectory of the stab injuries went below the diaphragm and injured the infradiaphragmatic inferior vena cava. Successful emergent repair via the thoraco-laparotomy approach revived the young man. In this report, we revisit and discuss previous large series of patients with this rare vena cava injury.
Reliability analysis for lateral stabilityof tongwamen bridge
Pan Sheng-Shan,Shi Lei,Tan Yong-Gang,Zhang Zhe 국제구조공학회 2011 Steel and Composite Structures, An International J Vol.11 No.5
Tongwamen Bridge is a critical link between Dongmen Island and the land in Shipu town, Zhejiang province, China. It is a 238 m span, half-through, concrete-filled steel tubular (CFST) X-type arch bridge. The width of the deck is only 10 m, yielding a width-to-span ratio of 1/23.8. The plane truss type section rib was adopted, which made of two CFST chords and web member system. The lateral stability is the key issue to this bridge. However, the existing researches on Tongwamen Bridge’s lateral stability are all the deterministic structural analysis. In this paper, a new strategy for positioning sampling points of the response surface method (RSM), based on the composite method combining RSM with geometric method for structural reliability analysis, is employed to obtain the reliability index of lateral stability. In addition the correlated parameters were discussed in detail to find the major factors. According to the analysis results, increasing the stiff of lateral braces between the arch ribs and setting the proper inward-incline degree of the arch rib can enhance obviously the reliability of lateral stability. Moreover, the deck action of non-orienting force is less than the two factors above. The calculated results indicate that the arch ribs are safe enough to keep excellent stability, and it provides the foundation that the plane truss rib would be a competitive solution for a long-span, narrow, CFST arch bridge.
Yan, Jian,Liu, Xiao-Long,Han, Lu-Zhe,Xiao, Gang,Li, Ning-Lei,Deng, Yi-Nan,Yin, Liang-Chun,Ling, Li-Juan,Yu, Xiao-Yuan,Tan, Can-Liang,Huang, Xiao-Ping,Liu, Li-Xin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
The aim of the present study was to investigate the expression of the transcription factor Ki-67, ER, PR, Her2/neu, p21, EGFR, and TOP II-${\alpha}$ in the tumor tissue of patients with invasive ductal carcinoma(IDC); in addition, we examined correlations between these markers. Two hundred and sixteen IDC patients, who were not previously been treated with chemo- or radiotherapy, were included in the study. All tumors were grade I-III. Expression of molecular markers was determined by immunohistochemical analysis on paraffin-embedded tissue sections. Follow-up data were collected for 3 months to 10 years and analyzed for tumor recurrence, survival time, and prognostic risk factors. We determined Ki-67 expression correlates with the expression of ER, PR, HER-2, EGFR, and TOP-${\alpha}$, as well as lymph node involvement, high tumor grade, lymphovascular invasion, high tumor stage, and high TNM stage in IDC. Positive Ki-67 expression was a risk factor for rapid tumor recurrence and may help tumor progression, leading to poor prognosis in IDC. Ki-67 was directly correlated with EGFR, TOP II-${\alpha}$, lymph node involvement, high tumor grade, lymphovascular invasion, high tumor stage, and high TNM stage in the hormone receptor subtypes of breast cancer. In triple negative breast cancer, Ki-67 correlated with TOP II-${\alpha}$. Expression of Ki-67 correlated with that of ER, PR, HER-2, EGFR, TOP II-${\alpha}$, and p21. In addition, the biomarker Ki-67 has a role as a prognostic factor and indicates a poor prognosis in IDC.