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51V-NMR Study of the Quasi-one-dimensional Antiferromagnet BaCo2V2O8
Yukiichi Ideta,Yu Kawasaki,Yutaka Kishimoto,Takashi Ohno,Yoshitaka Michihiro,Zhangzhen He,Yutaka Ueda,Mitsuru Itoh 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.3
We have investigated the magnetic properties of quasi-one-dimensional antiferromagnetBaCo2V2O8 by the measurements of 51V-NMR spectrum. With decreasing temperature, Kk showsa broad peak around 30 K signaling the 1D short-range order in the Co2+ spin chain. The estimatedWeiss temperature Θ = −105 K, hyperfine coupling constants Akhf = 2.1 kOe/µB for H k c and Ahf= 2.6 kOe/µB for H ⊥ c at 13 kOe are comparable to those at 70.6 kOe. These results suggest thatstatic magnetic properties in the paramagnetic state are nearly independent of external magneticfield, although the ground N´eel state is suppressed by the application of external magnetic fieldabove Hc = 39 kOe along c-axis. In the antiferromagnetic state below TN = 5.4 K, the doublerectangle-like powder pattern was observed, indicating two V sites exposed to different size of internalfields, HA1 = 2.1 and HA2 = 3.8 kOe. The internal fields at V sites are explained by takinginto account of the classical and pseudo-dipolar fields from Co2+ magnetic moments.
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Zhang, Zhen,He, Xujun,Xu, Ji,Zhang, Genhua,Yang, Yue,Ma, Jie,Sun, Yuanshui,Ni, Haibin,Wang, Fengyong The Korean Gastric Cancer Association 2020 Journal of gastric cancer Vol.20 No.2
Purpose: miR-205 is a tumor suppressor and plays an important role in tumor invasiveness. However, the role of miR-205 in human gastric cancer (GC) epithelial-mesenchymal transition (EMT) remains unclear. The aim of this study was to investigate the molecular mechanism of miR-205 in the regulation of EMT in GC invasion. Materials and Methods: Quantitative polymerase chain reaction (qPCR) was used to detect the expression of miR-205 in GC. Further, the correlation between the pathological parameters and prognosis of GC was statistically analyzed. A transwell model was used to evaluate the effect of miR-205-3p on the invasion and migration of GC cells. qPCR, western blotting, and luciferase assay were performed to analyze the relationship and target effects between miR-205-3p and the expression of zinc finger electron box binding homologous box 1 (ZEB1) and 2 (ZEB2). Results: We found that the levels of miR-205-3p were significantly lower (P<0.05) in GC tissues than in matched normal tissues. Additionally, the expression of miR-205-3p was related to the tumor invasion depth, lymph node metastasis, lymph node invasion, and tumor, node, metastasis stage. Patients with lower miR-205-3p expression levels in the tumors had a poorer prognosis. The in vitro assays indicated that miR-205-3p could affect the invasion ability and EMT of GC cells by targeting the expression of both ZEB1 and ZEB2. Conclusions: miR-205-3p promotes GC progression and affects the prognosis of patients by targeting both ZEB1 and ZEB2 to directly influence EMT.
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