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A novel flexible micro-ratchet/ZnO nano-rods surface with rapid recovery icephobic performance
Wang, Manxiang,Yu, Wenbo,Zhang, Yupei,Woo, Jae-Young,Chen, Yu,Wang, Bo,Yun, Yanbin,Liu, Guicheng,Lee, Joong Kee,Wang, Lei Elsevier 2018 Journal of industrial and engineering chemistry Vol.62 No.-
<P><B>Abstract</B></P> <P>In this communication, we present a significant method to fabricate a robust icephobic surface on a flexible polymer substrate. The flexible functional surface is obtained by integrating both soft-lithography and crystal growth methods. Modified by the materials with low surface free energy, the composite surface exhibits a robust superhydrophobicity at not only room temperature but also low temperature. After freezing test, the surface can recover to its original function quickly, which has achieved the level for industrial application, and also performed significant role for enhancing the icephobic theories.</P> <P><B>Highlights</B></P> <P> <UL> <LI> ZnO nano-rods are uniformly planted on the flexible PDMS surface. </LI> <LI> Fabrication of the surface integrates both crystal growth and physical vapor deposition methods. </LI> <LI> The superhydrophobic surface successfully realizes fast-recovery from freezing state. </LI> <LI> In freezing process, the nanorods can hardly cracked due to the flexible basement. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>The liquid droplet can recover to sphere state (Cassie's state) after melting from low temperature (for example, 20°C). ▪</P> <P>[DISPLAY OMISSION]</P>
A novel flexible micro-ratchet/ZnO nano-rods surface with rapid recovery icephobic performance
왕만상,Wenbo Yu,Yupei Zhang,우재영,Yucheng Du,Bo Wang,Yanbin Yun,유계성,이중기,Lei Wang 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.62 No.-
In this communication, we present a significant method to fabricate a robust icephobic surface on a flexible polymer substrate. The flexible functional surface is obtained by integrating both soft-lithography and crystal growth methods. Modified by the materials with low surface free energy, the composite surface exhibits a robust superhydrophobicity at not only room temperature but also low temperature. After freezing test, the surface can recover to its original function quickly, which has achieved the level for industrial application, and also performed significant role for enhancing the icephobic theories.
Yinji Liang,Chenli Lin,Yuanjun Deng,Yupei Zhang,Qinhe Yang 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.2
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in adults around China and the world. The study explores protective effect of traditional Chinese medicine Chaihu-Shugan-San decoction on high-fat diet-induced liver steatosis in rats via intestinal microbiota metabolite short-chain fatty acids (SCFAs) and its receptor Gpr43/109a. Fifteen male Sprague–Dawley rats were randomly divided into three groups of five rats each: the control group (standard diet), High-fat diet (HFD)-induced NAFLD group (83% standard diet + 10% lard oil + 5% sucrose + 1.5% cholesterol + 0.5% cholate), and Chaihu-Shugan-San (CSS)-treated group (HFD + 9.6 g/kg body weight gastric administration of CSS decoction every day). Body composition, hepatic fat, intestinal mucosal permeability and SCFAs, Gpr43 and Gpr109a expression in colonic tissues were assessed. Compared with NAFLD group, CSS decoction significantly reduced body weight, liver weight, hepatic triglyceride and total cholesterol (P < 0.05), and increased colonic SCFAs and occludin expression. The levels of Gpr43 and Gpr109a also changed significantly (P < 0.05). Protective effect of CSS decoction in HFD-induced NAFLD rats might improve intestinal mucosal permeability and intestinal microbiota metabolite SCFAs through Gpr43 and Gpr109a pathways in colonic tissues.
Liu, Xiaojun,Jiang, Yanan,Wu, Jianfu,Zhang, Wenjuan,Liang, Yupei,Jia, Lijun,Yu, Jinha,Jeong, L.S.,Li, Lihui Elsevier 2017 Biochemical and biophysical research communication Vol. No.
<P><B>Abstract</B></P> <P>It has been reported that MLN4924 can inhibit cell growth and metastasis in various kinds of cancer. We have reported that MLN4924 is able to inhibit angiogenesis through the induction of cell apoptosis both in vitro and in vivo models. Moreover, Neddylation inhibition using MLN4924 triggered the accumulation of pro-apoptotic protein NOXA in Human umbilical vein endothelial cells (HUVECs). However, the mechanism of MLN4924-induced NOXA up-regulation has not been addressed in HUVECs yet. In this study, we investigated how MLN4924 induced NOXA expression and cellular apoptosis in HUVECs treated with MLN4924 at indicated concentrations. MLN4924-induced apoptosis was evaluated by Annexin V-FITC/PI analysis and expression of genes associated with apoptosis was assessed by Quantitative RT-PCR and western blotting. As a result, MLN4924 triggered NOXA-dependent apoptosis in a dose-dependent manner in HUVECs. Mechanistically, inactivation of Neddylation pathway caused up-regulation of activating transcription factor 4 (ATF-4), a substrate of Cullin-Ring E3 ubiquitin ligases (CRL). NOXA was subsequently transactivated by ATF-4 and further induced apoptosis. More importantly, knockdown of ATF-4 by siRNA significantly decreased NOXA expression and apoptotic induction in HUVECs. In summary, our study reveals a new mechanism underlying MLN4924-induced NOXA accumulation in HUVECs, which may help extend further study of MLN4924 for angiogenesis inhibition treatment.</P> <P><B>Highlights</B></P> <P> <UL> <LI> MLN4924 triggered NOXA-dependent apoptosis in a dose-dependent manner in HUVECs. </LI> <LI> Inactivation of neddylation caused up-regulation of ATF4, a substrate of CRL. </LI> <LI> NOXA was transactivated by ATF4 and further induced apoptosis. </LI> <LI> Knockdown of ATF-4 significantly decreased NOXA expression and apoptotic induction. </LI> <LI> We revealed a new mechanism underlying MLN4924-induced NOXA accumulation in HUVECs. </LI> </UL> </P>
Role of Subordinate Phases on the Dry Impact‑Abrasion Behavior of Low Chromium Cast Iron
Yu Pei,Renbo Song,Yi Li,Zhiyang Zhao,Yingchao Zhang 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.12
In order to study the resistance mechanism of materials having high resistance to impact-abrasion, synergistic effect ofsubordinate phases of 2.20 wt%C–3.45 wt%Cr–3.06 wt%Mn–1.32 wt%Si–0.51 wt%Cu–0.31 wt%Ni–0.002 wt%B cast ironwas investigated under dry impact-abrasion. Subordinate phases consist of graphite, secondary precipitates and retainedaustenite. Results show that the synergistic effect of above subordinate phases can prevent matrix and carbide from peelingoff, and minimize the damage of carbide to matrix. This effect reduces the depth and width of groove from 7 to 1.2 μm andfrom 14 to 2.5 μm respectively. Above significant improvement is owing that: (1) Graphite can disperse external/internalstress, and fill carbide peeling pits. (2) Secondary precipitates, such as [Fe, Ni] and [Cr, Ni], can disperse the concentratedstress of carbide, inhibiting peeling. (3) Retained austenite can disperse the internal concentrated stress which is transferredfrom the carbide and fine precipitates to matrix.