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- 저자 : Younghae Kim (검색결과 72 건)
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Kim, Youngha,Kim, C-J,Jun, B-H,Sung, T H,Han, Y H,Han, S C,No, Kwangsoo IOP Publishing Ltd 2009 Superconductor science & technology Vol.22 No.6
<P>The influence of nanosized secondary particles, such as those produced via rare-earth doping for example, on magnetic-field-induced flux motion in YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7−δ</SUB> (YBCO)-coated conductors has been investigated. In this study, we investigated the influence of Ce doping on nanosized secondary phase formation in YBCO films. Ce-doped YBCO films on single SrTiO<SUB>3</SUB> crystals were prepared via metal–organic chemical vapor deposition (MOCVD). For the first time, a Y<SUB>2</SUB>BaCuO<SUB>5</SUB> (Y211) secondary phase was observed in the Ce-doped YBCO film, while the pure YBCO film contained only a Y<SUB>2</SUB>O<SUB>3</SUB> secondary phase. As Ce doping concentration increased to 3 wt%, a BaCeO<SUB>3</SUB> secondary phase developed. This was due to the low solubility limit of Ce for Y in the MOCVD YBCO film. Additionally, outgrowths on the Ce-doped YBCO film surfaces and defect structures, such as <I>a</I>-axis grains, were examined.</P>
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Dangerous border-collision bifurcations
Younghae Do,Sang Dong Kim,Philsu Kim,Hun Ki Baek 한국산업응용수학회 2006 한국산업응용수학회 학술대회 논문집 Vol.1 No.1
In this talk, we show our current results for dangerous border collision bifurcation characterized by exhibiting a stable fixed point before and after the critical bifurcation point, but the unbounded behavior of orbits at the critical bifurcation point. Dangerous bifurcations reveal a matter of serious concern for practical systems modeled by piecewise smooth maps, because there is no way of giving any signal of the impending collapse or unboundedness. Through the talk, we introduce the mechanism causing the occurrence of such bifurcations. Based on this mechanism, we find the qualitative type of the fixed point at the critical bifurcation value and show nonsmooth invariant manifolds of such fixed point, which can not be seen in linear systems.
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KIM, Youngha,SEO, Ji Hye,KIM, Hyeyoung Center for Academic Publications Japan 2011 JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY Vol.57 No.3
<P>Reactive oxygen species (ROS) including hydrogen peroxide (H<SUB>2</SUB>O<SUB>2</SUB>) are involved in the pathogenesis of gastric inflammation. Interleukin-8 (IL-8) is a potent mediator of the inflammatory response by activating and recruiting neutrophils to the site of infection. Oxidant-sensitive transcription factor NF-κB regulates the expression of IL-8 in the immune and inflammatory events. Carotenoids (carotenes and oxygenated carotenoids) show antioxidant and anti-inflammatory activities. Low intake of β-carotene leads to high risk of gastric cancer. Oxygenated carotenoid lutein inhibited NF-κB activation in experimental uveitis. The present study aims to investigate whether β-carotene and lutein inhibit H<SUB>2</SUB>O<SUB>2</SUB>-induced activation of NF-κB and expression of IL-8 in gastric epithelial AGS cells. The cells were treated with carotenoids 2 h prior to the treatment of H<SUB>2</SUB>O<SUB>2</SUB>. mRNA expression was analyzed by reverse transcription-polymerase chain reaction (RT-PCR) and real time RT-PCR analyses. IL-8 level in the medium was determined by enzyme-linked immunosorbent assay. NF-κB activation was assessed by electrophoretic mobility shift assay. ROS levels of the cells were detected by confocal microscopic analysis for fluorescent dichlorofluorescein. As a result, H<SUB>2</SUB>O<SUB>2 </SUB>induced the activation of NF-κB and expression of IL-8 in AGS cells time-dependently. β-Carotene and lutein showed inhibitory effects on H<SUB>2</SUB>O<SUB>2</SUB>-induced increase in intracellular ROS levels, activation of NF-κB, and IL-8 expression in AGS cells. In conclusion, supplementation of carotenoids such as β-carotene and lutein may be beneficial for the treatment of oxidative stress-mediated gastric inflammation.</P>
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Kim Youngha,Yoon Junghee,Kim Nayeon,Lee Mangyeong,Kang Danbee,Park Hye Yun,Oh Dongryul,Sung Ki-Sun,Suh Gee Young,Ahn Jin Seok,Cho Juhee 대한의학회 2021 Journal of Korean medical science Vol.36 No.33
Background: The purpose of the study was to translate and linguistically validate a Korean language version of the PROMIS (K-PROMIS) for the six profile adult domains: Fatigue, Pain Intensity, Pain Interference, Physical Function, Sleep Disturbance, and Ability to Participate in Social Roles and Activities. Methods: A total of 268 items were translated into Korean according to the Functional Assessment of Chronic Illness Therapy multilingual translation methodology. Participants first completed approximately 27 to 35 items and were then interviewed to evaluate the conceptual equivalence of the translation to the original English language source. The K-PROMIS items that met the a priori threshold of ≥ 20% of respondents with comprehension difficulties in the cognitive interview. Results: 54 of the 268 items were identified as difficult items to comprehend for at least 20% of respondents in Round 1. The most frequently identified K-PROMIS domain on difficult items to comprehend was the Physical function (24.5%). Most items with linguistic difficulties were Fatigue and Physical function. Cultural difficulties were only included the Physical function and Ability to Participate in Social Roles and Activities domains. 25 of 54 items were slightly revised, and then these revised items were tested with additional six participants in Round 2, and most participants had no problems to understand modified items. Conclusion: The six profile adult domains of K-PROMIS have been linguistically validated. Further psychometric validation of the K-PROMIS items will provide additional information of meaningful outcomes for chronic disease and clinical setting.
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정영해,김정숙,김재희 동신대학교 2004 論文集 Vol.14 No.-
The purpose of this study was to describe the practice of nurses working at the oriental medicine hospitals(OMH) and their knowledge needs for oriental nursing. The subjects were 164 nurses employed at 16 OMHs chosen from a total of 25 OMHs affiliated to 11 colleges of oriental medicine(OM) in Korea. The data were collected from June 1 to 15, 2002 using a survey questionnaire. The instruments used in this study included 41 items on the nursing practice at the OMHs, developed by the investigators based on the findings from previous studies (Kim, 1991; Lee et al, 1992; Chang & Han, 1992; Namkung, 2000), and 45 items of knowledge need for oriental nursing, which were also developed by the investigators based on the findings from previous studies, preliminary field study, and expert opinions. Data were analyzed using SPSS/PC for Windows program. The subjects' general characteristics were analyzed with frequency, percentage, mean, and standard deviation. The differences in nursing practice and knowledge need for oriental nursing by the characteristics were examined using t-test and ANOVA, and the correlations between nursing practice and knowledge need were examined with Pearson correlation coefficient. The results were as follows: 1. In terms of the characteristics related to the oriental nursing education, 57.9% reported not to take any nursing course on oriental nursing at college, 34.8% not to have any experience in participating an education class or seminar for oriental nursing, and 84.1% not to take any course credit for education for oriental nursing or seminar. The most common route of obtaining knowledge about oriental nursing was short courses provided with in the hospital (50.6%). Majority of subjects (92.0%) carried out oriental nursing practice feeling their level of knowledge on oriental nursing to be insufficient. It was reported that 49.4% experienced difficulties to communicate with OM doctors and 53.7% of the subjects had ever experienced difficulties to communicate with the clients because of their lack of knowledge on OM. 2. The average score of nursing practice was 3.84(±.48) out of the maximum of 5, showing a high frequency of nursing practice. Taking vital signs such as temperature, blood pressure, and pulse was the most common nursing practice with the score of 4.89(±.38), followed by making a nursing round, documenting nursing records, listening to the patients' complaints, carrying out the OM doctor's prescriptions, and documenting intake and output of the patients. On the other end of the scale, providing oral care using herbal medication was the least common nursing practice (1.98±1.02), followed by helping out bathing, providing meridian massage, and assisting OM doctors during treatments (moxibustion, cupping therapy). These findings show that nursing practice by the OM nurses was loaded heavily toward physical dimensions of nursing care, similar to that by nurses in western medicine. Nursing practice related to the OM was. not carried out actively. 3. The average score for knowledge need for oriental nursing was 3.99(±.57) out of the maximum of 5, showing a high level of need. Knowledge on herbal medication was the most needed with the score of 4.27(±.48), followed by the knowledge on direct nursing care, the knowledge on therapies (such as acupuncture, moxibustion, and cupping therapy), the knowledge on manipulation therapy, and the knowledge on types of acupuncture. Findings indicated a high level of knowledge needed for oriental nursing. The items with lower knowledge need were knowledge on diagnosis and treatment (3.72±71). 4. The level of nursing practice was significantly different among the subjects by their level of education (t=4.50, p=.0l2). The knowledge need for oriental nursing was significantly different according to their age(t=3.89, p=.010), marital status(t=2.51, p=.013), positions they held (t=3.64, p=.000), work experience(t3.28, p=.022), working unit (t=-2.10, p=.037), and education level(t=7.30, p=.001). 5. There was a statistically significant difference in the level of nursing practice by the perception of their own knowledge level(t=2.78, p= .006). Knowledge need for oriental nursing was shown to be different by class- and seminar-hours they had(t=3.95, p=.004), and the perception of their own knowledge level(t=284, p=.005). 6. There was a statistically significant positive correlation between the level of nursing practice and knowledge need for oriental nursing(r=.375, p=.000) Those who carried out nursing practice more frequently had higher level of knowledge need for oriental nursing. In summary, the level of nursing practice of the nurses working at OMHs was fairly high. However, the nurses felt they practice with insufficient level of knowledge on OM and had a high level of knowledge need for oriental nursing. Since the nursing practice at the OMHs was shown to be correlated with knowledge need for oriental nursing, nursing practice at the OMHs could be improved by increasing their level of knowledge about oriental nursing. Various educational programs are needed to be developed and implemented in order to effectively improve the level of knowledge about oriental nursing for the nurses working at OMHs. Better nursing service for clients of OMHs could be expected by enhanced knowledge about oriental nursing.
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