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Ka, Minhan,Park, Young-Un,Kim, Jinmi 충남대학교 생물공학연구소 2007 생물공학연구지 Vol.13 No.-
효모 Saccharomyces cerevisiae의 접합(mating)과 이형전환(filamentous growth)과정은 MAPK 신호전달체계에 의해서 조절을 받으며, Ste20와 Ste11, Ste7과 같은 kinase들과 Ste12 전사인자가 주요 조절요소이다. Keml/Xml단백질은 접합과 이형전환 시 MAPK신호전달체계의 하위단계에서 기능을 수행하며, 특히 핵융합(nuclear fusion)과정을 조절하는 Kar4 전사인자의 전사 후 조절(posttranscriptional regulation)에 관여한다. 본 논문에서는 keml돌연변이주의 핵융합 결함이 DHHI유전자의 과 발현을 통하여 회복됨을 확인하였다. 이는 keml 돌연변이주에서 DHHI유전자의 과 발현 시 Kar4단백질이 정상수준으로 회복되기 때문임을 확인할 수 있었다. 그러나 keml/keml 돌연변이주의 pseudohyphal growth에서의 결함은 DHHI 유전자의 과 발현에 의해서 회복되지 않는 것을 확인할 수 있었다. 이러한 결과를 토대로 효모의 접합과정에서 Keml과 Dhhl이 기능적으로 상호작용을 한다는 결론을 얻을 수 있었다.
A Study on Jeju Power System Considering Smart Grid Elements
Shin, Byoung-Yoon,Yoon, Minhan,Suh, Jae-Wan,Jang, Gilsoo,Choi, Hong-Seok,Seo, Young-Jun,Yoon, Dong-Hee 대한전기학회 2013 The Journal of International Council on Electrical Vol.3 No.4
Recently, smart grid has become a crucial issue and many studies have been conducted by various organizations and research institutions. The Korean government also developed smart grid roadmap and has invested for several years. Jeju is the largest island in Korea with high wind penetration and quality. In the coming years, there are plans to reduce thermal units and increase renewable energy such as WT & PV in Jeju Island. Moreover, The Korean government selected Jeju as one of the sites for electric vehicle propagation. In particular, Jeju has been operating the Smart Grid Test-bed for the next-generation energy systems. Therefore, effects of the smart grid elements and their combination could be checked by simulations of these elements implemented onto the Jeju power system. In this paper, the stability of the Jeju power system is investigated considering the various changes owing to the smart grid elements such as renewable sources, EV and HVDC.
사향쥐(Ondrtra cuniculus)의 정착 및 서식지 이용에 관한 연구
김영채,홍선희,이창우,김아름,박희복,박수곤,김민한,이도훈,Kim, Young-Chae,Hong, Sun Hee,Lee, Changwoo,Kim, Areum,Park, Heebok,Park, Su-Gon,Kim, Minhan,Lee, Do-Hun 한국환경생물학회 2020 환경생물 : 환경생물학회지 Vol.38 No.1
본 연구는 침입종 사향쥐의 국내 자연생태계 정착 여부를 확인하였다. 아울러 관리전략 수립과 현장 관리에 필수적인 관리대상지역과 기초적인 행동특성 정보, 서식지 이용에 관한 자료를 제공하고자 하였다. 이를 위해 해외의 사향쥐 관리 동향을 파악하여 정착 단계에 따른 관리 방향을 검토하였다. 그리고 국내 72개 사육농가의 위치정보를 확보하였고, 실태조사를 통해 경기도, 충청남도, 경상북도, 세종특별자치시 소재 5개 지역을 자연 유출 가능성이 높은 지역으로 제시하였다. 또한, 2016년부터 2018년까지 3년간 동일 지점에 서식하는 개체를 모니터링하였다. 2018년 모니터링 지역에서 포획한 개체의 연령이 1.2년생으로 확인되었으며, 2012년 이후 해당지역에 추가적인 개체 보충이 없었다는 사실에 근거하여 국내 자연생태계에 사향쥐가 정착한 것으로 판단하였다. 국내 자연에 정착한 사향쥐는 0.0027 ㎢ (MCP 95%)의 작은 행동권을 나타내었으며, 봄철과 가을철 규칙적인 이동성을 보이는 것으로 나타났다. 사향쥐의 서식이 관찰된 지역은 서식환경의 교란이 높게 발생한 지역이었으며, 사향쥐의 흔적 출현 빈도는 부엽식물과 부유식물의 생육이 왕성한 개방수역과 개체의 은신처로 활용 가능한 습생목본 식생유형에서 높게 확인되어 이들의 생태적 특성과 섭식 습성이 그대로 반영되었다. 국제적인 침입종 사향쥐가 국내 생태계에 정착하였고, 향후 확산이 우려되는 만큼 정부 차원의 선제적 대응과 과학적 관리를 위한 필수 자료 구축이 검토될 필요가 있다. This study was conducted to determine whether invasive muskrats settle in the natural ecosystem of Korea. The study also aimed to provide information on the selection of target areas, basic behavioral characteristics, and habitat use-related data, all of which are essential for effective management strategy establishment and site management. To this end, a trend in international muskrat management was identified to examine the management direction according to the settlement stage. We also secured the location of 72 domestic farmers and classified five regions in Gyeonggi-do, Chungcheongnam-do, Gyeongsangbuk-do, and Sejong Special Self-governing City into regions with high potential for natural leakage to raise the need for a quick survey. We determined that muskrats successfully settled in the natural ecosystem of Korea, based on the fact that we consistently identified a muskrat habitat at the same point for three years, from 2016 to 2018, the age of the captured population was estimated to be 1.2 years, and there had been no additional make-up factors near the habitat since 2012. The muskrats that settled in Korea showed a small home range of 0.0027 ㎢ (MCP 95%) and were estimated to show regular mobility before Spring and Autumn. Also, the areas where the muskrat habitat was observed had a high level of habitat environment disturbance and their ecological and food intake characteristics reflected that disturbance. Muskrat traces were high in hydrophyte vegetation, which can be used as a hideout in open waters and where the growth of both floating leaved plants and floating plants are prevalent. Since international invasive muskrats have already settled in the domestic ecosystem and there is concern about their proliferation in the future, the government must consider a preemptive response and scientific management.
Jeong-MinLee,In-HwanKim,Hyo-SungKwak,Ji-HyunYouk,Young-MinHan,Chong-SooKim 대한영상의학회 2003 Korean Journal of Radiology Vol.4 No.1
Objective: To compare the performance of superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance (MR) imaging at 1.5T and dual-phase spiral computed tomography (CT) for the depiction of small hypervascular hepatocellular carcinomas (HCCs). Materials and Methods: Forty-three patients with 70 small nodular HCCs (5-20 mm; mean, 13.7 mm) were examined. Diagnosis was based on the results of surgical biopsy in 22 patients and by the combined assessment of MR imaging, lipiodol CT, alpha feto-protein levels, and angiographic findings in 21. MR imaging consisted of respiratory-triggered turbo spin-echo T2-weighted imaging, T1- weighted fast low-angle shot, and T2 -weighted fast imaging with steady-state precession imaging before and after SPIO enhancement. CT imaging was performed with 5-mm collimation and 1:1.4 pitch, and began 30 and 65 secs after the injection of 150 mL of contrast medium at a rate of 3 mL/sec. Two blinded observers reviewed all images independently on a segment-by-segment basis. Diagnostic accuracy was evaluated using receiver operating characteristics (ROC) analysis. Results: The mean areas (Az) under the ROC curves were 0.85 for SPIOenhanced MR imaging and 0.79 for dual-phase spiral CT (p < .05). The mean sensitivity of SPIO-enhanced MR imaging was significantly higher than that of CT (p < .05), i.e. 70.6% for MR imaging and 58.1% for CT. MR imaging had higher false-positive rates than dual-phase spiral CT, but the difference was not statistically significant (3.7% vs 3.3%) (p > .05). Conclusion: SPIO-enhanced MR imaging is more sensitive than dual-phase spiral CT for the depiction of small hypervascular hepatocellular carcinomas.