Discrepancy between Clinician-rated and Self-reported Depression Severity is Associated with Adverse Childhood Experience, Autistic-like Traits, and Coping Styles in Mood Disorders

Risa Yamada(Risa Yamada ),Takeshi Fujii(Takeshi Fujii ),Kotaro Hattori(Kotaro Hattori ),Hiroaki Hori(Hiroaki Hori ),Ryo Matsumura(Ryo Matsumura ),Tomoko Kurashimo(Tomoko Kurashimo ),Naoko Ishihara(Nao 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.2

Objective: This study aimed to determine if the discrepancy between depression severity rated by clinicians and that reported by patients depends on key behavioral/psychological features in patients with mood disorders. Methods: Participants included 100 patients with mood disorders. First, we examined correlations and regressions between scores on the Hamilton Depression Rating Scale (HAMD) and Beck Depression Inventory (BDI). Second, we divided the participants into those who provided 1) greater ratings for the BDI compared with the HAMD (BDI relative- overrating, BO) group, 2) comparable ratings for the BDI and HAMD (BDI relatively concordant, BC) group, or 3) less ratings for the BDI (BDI relative-underrating, BU) group. Adverse childhood experiences, autistic-like traits, and coping styles were evaluated with a six-item short version of the Childhood Trauma Questionnaire (CTQ-6), the Social Responsiveness Scale for Adults (SRS-A), and the Ways of Coping Checklist (WCCL), respectively. Results: A significant correlation was found between HAMD and BDI scores. Total and emotional abuse subscale scores from the CTQ-6, and the self-blame subscale scores from the WCCL were significantly higher for the BO group compared with the BU group. The BO group also elicited significantly higher SRS-A total scores than did the other groups. Conclusion: These findings suggest that patients with adverse emotional experiences, autistic-like traits, and self-blame coping styles perceive greater distress than that evaluated objectively by clinicians. The results indicate the need for inclusion of subjective assessments to effectively evaluate depressive symptoms in patients deemed to have these psycho- behavioral concerns.

Electrical Properties of Planar-type Magnetic Tunnel Junction Covered with Insulating Layer

Shogo Yamada,Tsutomu Yamada,Jun-ichi Shirakashi,Yasushi Takemura 한국자기학회 2007 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

New Development of Tailor-made Peptide Vaccine for Cancer Immunotherapy

Akira, Yamada,Hideaki, Yamada,Kyogo, Itoch 가톨릭 의과학연구원 2003 가톨릭 의과학연구원 국제학술대회 Vol.7 No.-

Evaluation of 131I (monoiodide) BSP for Clinical Studies

Ueda, Hideo,Iro, Masahiro,Kurata, Kunio,Yamada, Hideo,Iwase, Tohru,Migita, Tohru,Kameda, Haruo,Kato, Sadatake,Sato, Noboru,Ide, Kazuko,Wakebayashi, Takao 대한핵의학회 1971 핵의학 분자영상 Vol.5 No.1

"In 1925 Rosenthal and White introduced a bromosulfophthalein (BSP) dye retention test as a sensitive indicator of liver function. Even now it is regared as one of the most sensitive agents for the detection of non-icteric liver disease (liver cirrhosis, early stage of acute-hepatitis and hepatic tumor). BSP accumulates in the liver cells, conjugates with glutathione and is excreted into the bile. Therefore, a disorder in its excretion is due to a disturbance of one of these processes. Since bilirubin and BSP compete for uptake by the liver and increased serum bilirubin interferes with the colorimetric determination of BSP, it has been considered that BSP test is inappropriate for the differential diagnosis of jaundice conditions. It has been generally said that when jaundice is present, the BSP test is useless and should not be performed. In 1955, Taplin et al. labeled rose bengal, a dye similarly metabolized in the liver as BSP, with 131I and measured the hepatic excretion of this dye by external monitoring. Laster, Blahd et al. applied this method to the determination of the peripheral pool, succeeding in the diagnosis of chronic and subacute hepatic diseases without colorimetry. In 1968, Yamada, Taplin et al. suggested the possibility of differentiating so-called medical jaundice from surgical jaundice by scanning the subjects during 24 to 48 hours following intravenous injection of 131I-labeled rose bengal. As mentioned before, many authorities hold the opinion that BSP is not proper for the differential diagnosis of jaundice states. Some have tried to diagnose biliary tract obstruction by a malignant tumor by measuring BSP excretion into duodenal fluid and others by quantitating changes in serum levels of conjugated and free BSP. Furthermore, Burton et al. reported that in patients with extrahepatic obstructive jaundice, BSP retention was observed for 24 days after its administration. From a consideration of all these finding we came to a conclusion that the differential diagnosis of various jaundice states, (medical, surgical and constitutional) is possible by sequential scanning with radioisotope-labeled BSP, as with rose bengal, in accordance with procedures described by Yamada, Taplin et al. The evidence suggested that labeled BSP might make a more important contribution than rose bengal. "

Second-harmonic generation in a silicon-carbide-based photonic crystal nanocavity

Yamada, S.,Song, B.-S.,Jeon, S.,Upham, J.,Tanaka, Y.,Asano, T.,Noda, S. OPTICAL SOCIETY OF AMERICA 2014 Optics letters Vol.39 No.7

Study of the cartilage matrix production-promoting effect of chicken leg extract and identification of the active ingredient

Yamada, Hiroaki,Nakamura, Utano,Nakamura, Toshio,Uchida, Yoshikazu,Yamatsu, Atsushi,Kim, Mujo The Korean Nutrition Society 2019 Nutrition Research and Practice Vol.13 No.6

BACKGROUND/OBJECTIVES: Osteoarthritis (OA) is a major public health issue in Japan and other countries, and foods that prevent or treat OA are in strong demand. Proteins and peptides in chicken meat and bones are known for being rich in functional and nutritional ingredients for the improvement of osteoporosis. We speculated that chicken legs, a food consumed in many regions of the world, may also contain such ingredients. In this study, we aim to (i) evaluate the effect of chicken leg extract (CLE) on the promotion of cartilage matrix production and (ii) identify the active ingredient in CLE that contributes to this function. MATERIALS/METHODS: Artificial CLE digest was prepared, and the acid mucopolysaccharide production-promoting activity of the CLE digest was evaluated by alcian blue staining of ATDC5 cells. CLE was orally administered to rabbits with burr holes in the knee joint of the femur, and the degree of regeneration of cartilage matrix was evaluated. Furthermore, we investigated orally administered CLE-derived peptides in human plasma using LC-MS. From measuring the acid mucopolysaccharide production-promotion activity of these peptides, a molecule considered to be an active ingredient in the CLE digest was identified. RESULTS: CLE digest promoted acid mucopolysaccharide production and facilitated regeneration of cartilage matrix in in vitro and in vivo experiments. Four peptides including phenylalanyl-hydroxyproline (Phe-Hyp) were detected as CLE-derived peptides in human plasma. The effect of CLE was inferred to be due to Phe-Hyp, which was confirmed to be present in the CLE digest. CONCLUSIONS: It was shown that CLE stimulated the production of articular cartilage matrix both in vitro and in vivo, and that CLE could be an effective food for preventing or treating OA. Furthermore, only Phe-Hyp was confirmed as the active compound in the CLE digest, suggesting that the activity of CLE was due to Phe-Hyp.

LaCoO₃ acting as an efficient and robust catalyst for photocatalytic water oxidation with persulfate

Yamada, Yusuke,Yano, Kentaro,Hong, Dachao,Fukuzumi, Shunichi The Royal Society of Chemistry 2012 Physical chemistry chemical physics Vol.14 No.16

<P>Cobalt-containing metal oxides [perovskites (LaCoO<SUB>3</SUB>, NdCoO<SUB>3</SUB>, YCoO<SUB>3</SUB>, La<SUB>0.7</SUB>Sr<SUB>0.3</SUB>CoO<SUB>3</SUB>), spinel (Co<SUB>3</SUB>O<SUB>4</SUB>) and wolframite (CoWO<SUB>4</SUB>)] have been examined as catalysts for photocatalytic water oxidation with Na<SUB>2</SUB>S<SUB>2</SUB>O<SUB>8</SUB> and [Ru(bpy)<SUB>3</SUB>]<SUP>2+</SUP> as an electron acceptor and a photosensitizer, respectively. Catalysts with the perovskite structure exhibited higher catalytic activity as compared with the catalysts with the spinel and wolframite structures. LaCoO<SUB>3</SUB>, which stabilizes Co(<SMALL>III</SMALL>) species in the perovskite structure, exhibited the highest catalytic activity in the photocatalytic water oxidation compared with CoWO<SUB>4</SUB>, Co<SUB>3</SUB>O<SUB>4</SUB> and La<SUB>0.7</SUB>Sr<SUB>0.3</SUB>CoO<SUB>3</SUB> which contain Co(<SMALL>II</SMALL>) or Co(<SMALL>IV</SMALL>) species in the matrices. The high catalytic reactivity of LaCoO<SUB>3</SUB> possessing perovskite structure was maintained in NdCoO<SUB>3</SUB> and YCoO<SUB>3</SUB> which exclusively contain Co(<SMALL>III</SMALL>) species. Thus, the catalytic activity of Co ions can be controlled by the additional metal ions, which leads to development of highly reactive and robust catalysts for the photocatalytic water oxidation.</P> <P>Graphic Abstract</P><P>Co-containing metal oxides were used as catalysts for photocatalytic water oxidation. Among them LaCoO<SUB>3</SUB> exhibited the highest catalytic activity, upon being used repeatedly without losing the catalytic activity. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cp00022a'> </P>

Japanese Residents in Korea and the Modernization of Chosŏn

Yamada Ryosuke(算田良介) 고려대학교 한국사연구소 2006 International Journal of Korean History Vol.10 No.-

세계사에 있어서의 보편성을 중시하면서 조선의 「근대」를 생각했을 경우, 개항 이후 소위 「근대 이행기」(近代移行期)에 생기는 민중운동은, 시기적인 차이는 있지만, 같은 상황에 있던 일본이나 유럽 등의 타지역과 유사한 현상으로서 해석하는 것이 가능이라고 생각된다. 또, 한반도에서의 민중운동을 고찰하는 경우, 이른바 「재조 일본인」(在朝日本人 일본인 거류민)과의 관계를 간과할 수 없다. 「재조 일본인」과 한반도에 있어서의 「근대」의 문제를 연관시킨다면, 다음과 같은 전망을 제시 할 수 있다고 생각한다. 한반도에 있어 상업 등에 종사한 일본인은 근대적 규범-「폴리티컬 이코노미」(Political Economy)-에 의거해 그들의 행위를 정당화했지만, 전통적 규범-「모랄ㆍ이코노미」(Moral Economy)-에 입각해 행동을 일으키는 조선인 측과 분쟁이 생겼을 때, 그들은 정치적인 힘 관계에 의해 자신들의 주장을 관철시켰다. 이러한 분쟁처리 과정의 반복으로 인해서 조선 내에서 종래의 전통적 규범에 의거하는 행위는 점차 효력을 잃어 가게 되었다. 한반도에 거주하는 일본인들은 이러한 의미에서 조선의 「근대화」를 추진시키는 담당자의 일부가 된 것이 아닌가? 본고는, 이상과 같은 가설을 검증하기 위해서 청일 전쟁 후의 한반도에서의 방곡령(防穀令)을 둘러싼 조일(朝日)간의 분쟁을 사례로 한 기초 작업이다.

How Many Roads must be Named after him? The Politics of Naming Streets after Bob Dylan in Minnesota

Yamada harumichi 대한지리학회 2011 대한지리학회 컨퍼런스 자료집 Vol.- No.6

Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations

Yamada, Y.,Nishida, T.,Ichihara, S.,Sawabe, M.,Fuku, N.,Nishigaki, Y.,Aoyagi, Y.,Tanaka, M.,Fujiwara, Y.,Yoshida, H.,Shinkai, S.,Satoh, K.,Kato, K.,Fujimaki, T.,Yokoi, K.,Oguri, M.,Yoshida, T.,Watanab Elsevier Scientific Publ. Co 2011 Atherosclerosis Vol.215 No.1

Objective: We have performed a genome-wide association study (GWAS) to identify genetic variants that confer susceptibility to myocardial infarction (MI) in Japanese and Korean populations. Methods: A total of 17,447 Japanese or Korean individuals from four independent subject panels was examined. Japanese subject panels A, B, and C comprised 134 individuals with MI and 137 controls, 1431 individuals with MI and 3161 controls, and 643 individuals with MI and 1347 controls, respectively, whereas the Korean population comprised 1880 individuals with MI and 8714 controls. A GWAS for MI was performed in Japanese subject panel A with the use of the Affymetrix GeneChip Human Mapping 500K Array Set. Results: Seventy single nucleotide polymorphisms (SNPs) significantly (P<1.0x10<SUP>-7</SUP>) associated with MI by the GWAS were examined further in Japanese subject panel B, revealing two SNPs (rs6929846 of BTN2A1, rs2569512 of ILF3) to be significantly (P<0.0007) associated with MI. The rs6929846 SNP of BTN2A1, but not rs2569512 of ILF3, was also significantly associated with MI in Japanese subject panel C. However, the association of neither rs6929846 nor rs2569512 with MI was replicated in the Korean population. Conclusion: BTN2A1 may be a susceptibility gene for MI in Japanese individuals.