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- 저자 : Xiangcheng Wu (검색결과 5 건)
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Xiangcheng Wu,Changqi Yan,Zhaoming Meng,Kailun Chen,Shaochuang Song,Zonghao Yang,Jie Yu 한국원자력학회 2016 Nuclear Engineering and Technology Vol.48 No.6
To get an insight into the operating characteristics of the passive residual heat removalsystem of molten salt reactors, a two-phase natural circulation test facility was constructed. The system consists of a boiling loop absorbing the heat from the drain tank, acondensing loop consuming the heat, and a steam drum. A steady-state experiment wascarried out, in which the thimble temperature ranged from 450℃ to 700℃ and the systempressure was controlled at levels below 150 kPa. When reaching a steady state, the systemwas operated under saturated conditions. Some important parameters, including heatpower, system resistance, and water level in the steam drum and water tank wereinvestigated. The experimental results showed that the natural circulation system isfeasible in removing the decay heat, even though some fluctuations may occur in theoperation. The uneven temperature distribution in the water tank may be inevitablebecause convection occurs on the outside of the condensing tube besides boiling withdecreasing the decay power. The instabilities in the natural circulation loop are sensitive toheat flux and system resistance rather than the water level in the steam drum and watertank. RELAP5 code shows reasonable results compared with experimental data.
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Xueyun Wu,Zhengbin Lv,Yaozhou Zhang,Dong Yang,Xiangcheng Zhu,Zhinan Xu,Zhiyang Feng,Ben Shen 한국생물공학회 2010 Biotechnology and Bioprocess Engineering Vol.15 No.4
The heterologous production of iso-migrastatin (iso-MGS) was successfully demonstrated in an engineered S. lividans SB11002 strain, which was derived from S. lividans K4-114, following introduction of pBS11001,which harbored the entire mgs biosynthetic gene cluster. However, under similar fermentation conditions, the iso-MGS titer in the engineered strain was significantly lower than that in the native producer - Streptomyces platensis NRRL 18993. To circumvent the problem of low iso-MGS titers and to expand the utility of this heterologous system for iso-MGS biosynthesis and engineering, systematic optimization of the fermentation medium was carried out. The effects of major components in the cultivation medium,including carbon, organic and inorganic nitrogen sources,were investigated using a single factor optimization method. As a result, sucrose and yeast extract were determined to be the best carbon and organic nitrogen sources, resulting in optimized iso-MGS production. Conversely, all other inorganic nitrogen sources evaluated produced various levels of inhibition of iso-MGS production. The final optimized R2YE production medium produced iso-MGS with a titer of 86.5 mg/L, about 3.6-fold higher than that in the original R2YE medium, and 1.5 fold higher than that found within the native S. platensis NRRL 18993 producer.
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Zhang, Xiaoyan,Wu, Xianfeng,Jia, Wenchao,Pan, Chuanying,Li, Xiangcheng,Lei, Chuzhao,Chen, Hong,Lan, Xianyong Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.10
The AT motif-binding factor (ATBF1) not only interacts with protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) to suppress STAT3 signaling regulating embryo early development and cell differentiation, but is required for early activation of the pituitary specific transcription factor 1 (Pit1) gene (also known as POU1F1) critically affecting mammalian growth and development. The goal of this study was to detect novel nucleotide variations and haplotypes structure of the ATBF1 gene, as well as to test their associations with growth-related traits in goats. Herein, a total of seven novel single nucleotide polymorphisms (SNPs) (SNP 1-7) within this gene were found in two well-known Chinese native goat breeds. Haplotypes structure analysis demonstrated that there were four haplotypes in Hainan black goat while seventeen haplotypes in Xinong Saanen dairy goat, and both breeds only shared one haplotype (hap1). Association testing revealed that the SNP2, SNP5, SNP6, and SNP7 loci were also found to significantly associate with growth-related traits in goats, respectively. Moreover, one diplotype in Xinong Saanen dairy goats significantly linked to growth related traits. These preliminary findings not only would extend the spectrum of genetic variations of the goat ATBF1 gene, but also would contribute to implementing marker-assisted selection in genetics and breeding in goats.
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Xiaoyan Zhang,Xianfeng Wu,Wenchao Jia,Chuanying Pan,Xiangcheng Li,Chuzhao Lei,Hong Chen,Xianyong Lan 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.10
The AT motif-binding factor (ATBF1) not only interacts with protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) to suppress STAT3 signaling regulating embryo early development and cell differentiation, but is required for early activation of the pituitary specific transcription factor 1 (Pit1) gene (also known as POU1F1) critically affecting mammalian growth and development. The goal of this study was to detect novel nucleotide variations and haplotypes structure of the ATBF1 gene, as well as to test their associations with growth-related traits in goats. Herein, a total of seven novel single nucleotide polymorphisms (SNPs) (SNP 1-7) within this gene were found in two well-known Chinese native goat breeds. Haplotypes structure analysis demonstrated that there were four haplotypes in Hainan black goat while seventeen haplotypes in Xinong Saanen dairy goat, and both breeds only shared one haplotype (hap1). Association testing revealed that the SNP2, SNP5, SNP6, and SNP7 loci were also found to significantly associate with growth-related traits in goats, respectively. Moreover, one diplotype in Xinong Saanen dairy goats significantly linked to growth related traits. These preliminary findings not only would extend the spectrum of genetic variations of the goat ATBF1 gene, but also would contribute to implementing marker-assisted selection in genetics and breeding in goats.
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Wang Qiang,Yu Pengyao,Lv Mingdong,Wu Xiangcheng,Li Chenfeng,Chang Xin,Wu Lihong 대한조선학회 2024 International Journal of Naval Architecture and Oc Vol.16 No.-
Real-time acquisition of wave-induced hull girder loads of a sailing ship will help the captain make reasonable decisions, which is of great significance for improving the safety of the ship’s navigation. This paper investigates the real-time prediction method of hull girder loads based on the Recurrent Neural Network (RNN) model and error correction strategy. Firstly, taking the vertical bending moment, horizontal bending moment, and torsional moment at the mid-ship position of a large container ship as examples, corresponding neural network prediction models are established through parameter influence analysis. Secondly, various sea state conditions are used to verify the feasibility of established network prediction models to predict the hull girder loads in real-time. The VBM prediction model performs better than the TM prediction model and HBM prediction model, and the errors of the TM prediction model and HBM prediction model are slightly larger in some cases. Lastly, an improved prediction model based on an error correction strategy is proposed to improve the prediction accuracy of the neural network prediction model, and the adequate performance of the error correction strategy is discussed.
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