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- 저자 : Siew Leng Tan (검색결과 4 건)
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An Ultra-precision Electronic Clinometer for Measurement of Small Inclination Angles
Tan, Siew-Leng,Kataoka, Satoshi,Ishikawa, Tatsuya,Ito, So,Shimizu, Yuuki,Chen, Yuanliu,Gao, Wei,Nakagawa, Satoshi The Korean Society of Manufacturing Technology Eng 2014 한국생산제조학회지 Vol.23 No.6
This paper describes an ultra-precision electronic clinometer, which is based on the capacitive-based fluid type, for detection of small inclination angles. The main parts of the clinometer low-noise electronics are two capacitance measurement circuits for converting the capacitances of the capacitors of the clinometer into voltages, and a differential amplifier for obtaining the difference of the capacitances, which is proportional to the input inclination angle. A 16 bit analog to digital (AD) converter is also embedded into the same circuit board, whose output is sent to a PC via RS-232C, for achieving a small noise level down to tens of ${\mu}v$. A compensation method, which is referred to as the delay time method for shortening the stabilization time of the sensor was also discussed. Experimental results have shown the possibility of achieving a measurement resolution of $0.0001^{\circ}$ as well as the quick measurement with the delay time method.
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Siew Leng Tan,Yuki Shimizu,Takayuki Meguro,So Ito,Wei Gao 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.
This paper presents the design and construction of a laser autocollimator-based optical sensor for measurement of the tilt angles ofa reflector mounted on the guideways or the moving table of a precision linear slide in the production process of the slide, wherethe measurement is repeatedly carried out together with a hand scraping operation for correction of the form errors of the slideguideways. Differing from a conventional autocollimator, a laser rangefinder unit is integrated with the autocollimation unit fordetection of the positions of the reflector, which is necessary for the efficient error correction of the slide guideways. Theautocollimation unit and the rangefinder unit share the same light source for a compact optical design. The optical power of the laserbeam is first set to be constant for tilt angles measurement. Then the optical power is modulated with a frequency of 66.7 MHz formeasuring the position/distance based on the phase shift method. The resolution of the laser autocollimator is confirmed to be 0.2arc-second over a range of ±50 arc-seconds while the measurement positions can be detected with a resolution of 1 mm by therangefinder, which satisfies the requirements from production of the slide.
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An Ultra-precision Electronic Clinometer for Measurement of Small Inclination Angles
Siew?Leng Tan,Satoshi Kataoka,Tatsuya Ishikawa,So Ito,Yuuki Shimizu,Yuanliu Chen,Wei Gao,Satoshi Nakagawa 한국생산제조학회 2014 한국생산제조학회지 Vol.23 No.6
This paper describes an ultra-precision electronic clinometer, which is based on the capacitive?based fluid type, for detection of small inclination angles. The main parts of the clinometer low?noise electronics are two capacitance measurement circuits for converting the capacitances of the capacitors of the clinometer into voltages, and a differential amplifier for obtaining the difference of the capacitances, which is proportional to the input inclination angle. A 16 bit analog to digital (AD) converter is also embedded into the same circuit board, whose output is sent to a PC via RS-232C, for achieving a small noise level down to tens of μv. A compensation method, which is referred to as the delay time method for shortening the stabilization time of the sensor was also discussed. Experimental results have shown the possibility of achieving a measurement resolution of 0.0001° as well as the quick measurement with the delay time method.
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Siew Lian Chong,Asral Wirda Ahmad Asnawi,Tze Shin Leong,Jenq Tzong Tan,Kian Boon Law,Siong Leng Hon,Rui Jeat Fann,Sen Mui Tan 대한혈액학회 2021 Blood Research Vol.56 No.3
Background With the emergence of tyrosine kinase inhibitors and the incorporation of stringent measurable residual disease (MRD) monitoring, risk stratification for BCR-ABL1-positive acute lymphoblastic leukemia (ALL) patients has changed significantly. However, whether this monitoring can replace conventional risk factors in determining whether patients need allogeneic stem cell transplantation is still unclear. This study aimed to determine the impact of BCR-ABL1 monitoring on the outcome of patients with BCR-ABL1-positive ALL after allogeneic stem cell transplantation. Methods We retrospectively analyzed the survival outcome of patients with BCR-ABL1-positive ALL based on the quantification of BCR-ABL1 at 3 timepoints: the end of induction (timepoint 1), post-consolidation week 16 (timepoint 2), and the end of treatment for patients who were either transplant-eligible or non-transplant eligible (timepoint 3). Results From 2006 to 2018, a total of 96 patients newly diagnosed with BCR-ABL1-positive ALL were treated with chemotherapy and tyrosine kinase inhibitors. Thirty-eight (41.3%) patients achieved complete remission, and 33 patients underwent allogeneic stem cell transplantation. Our data showed that pre-transplant MRD monitoring by real-time quantitative polymerase chain reaction had the highest correlation with survival in patients with BCR-ABL1-positive ALL, especially for those who underwent allogeneic stem cell transplantation. Conclusion Patients without MRD pre-transplantation had superior survival compared with those who had MRD, and they had excellent long-term outcomes after allogeneic stem cell transplantation.
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