Double Rhythm The Rainbow and Women in Love as an "Organic Whole"

Shunji Suzuki 한국로렌스학회 2007 D.H. 로렌스 연구 Vol.15 No.1

The Rainbow and Women in love were originally to be written as one novel, Sisters, but as the result of the First World War, Lawrence could not continue writing Sisters, which eventually became two separate works Lawrence insists even after the publication of the two novels that they are a kind of "sequel" or an "organic artistic whole" F. R. Leavis and others, however, do not agree with Lawrence in this respect, and argue that the two novels should be read as separate works Is Lawrence wrong when he insists that they should make an "organic whole"? In reading Lawrence's novels, we need to pay attention to the "organic" relation of the various elements, such as characters, images, and the background of nature, which makes the "rhythmic form" So we should examine the "double rhythm of creating and destroying" (quoted from Studies in Classic American Literature) flowing through the two novels This paper attempts to demonstrate that the "double rhythm" falling down through The Rainbow finally goes toward the Lawrentian paradise of true being in Women in Love, and that the two novels can be read as a kind of "organic whole. "

Antimicrobial Resistance for Chlamydia Trachomatis Genital Infection during Pregnancy in Japan

Suzuki Shunji,Hoshi Shin-ichi,Sagara Yoko,Sekizawa Akihiko,Kinoshita Katsuyuki,Kitamura Tadaichi 대한감염학회 2022 Infection and Chemotherapy Vol.54 No.1

The current study examined the antimicrobial resistance of Chlamydia trachomatis (CT) genital infection during pregnancy in Japan. We requested 2,146 obstetrical facilities that are members of Japan Association of Obstetricians and Gynecologists to provide information of CT screening tests and antimicrobial resistance in pregnant women between April 2020 and March 2021. The prevalence of CT genital infection in Japan was 2.1%. The antimicrobial resistance was recognized in 2.0 and 2.4% of the cases using azithromycin and clarithromycin, respectively. There were no significant differences in the antimicrobial resistance rate between the 2 analogues (P = 0.28). In Japan, azithromycin and clarithromycin have effectively treated genital CT infections during pregnancy.

Improvement of Transformation Efficiency by Strategic Circumvention of Restriction Barriers in Streptomyces griseus

( Suzuki Hirokazu ),( Shunji Takahashi ),( Hiroyuki Osada ),( Ken Ichi Yoshida ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.7

DNA methylation in Streptomyces griseus IFO 13350 was analyzed by high-performance liquid chromatographic analysis and bisulfite-based analysis to reveal two methylation sites, 5`-GC5mCGGC-3` and 5`-GAG5mCTC-3`. The methylation was reconstituted in Escherichia coli by simultaneous expression of S. griseus SGR4675 and S. achromogenes M.SacI. The E. coli cells produced plasmids that mimicked the methylation profile of S. griseus DNA, which was readily introduced into S. griseus. The results of this study raise the possibility of a promising approach to establish efficient transformation in several streptomycetes.

Characterization of phenolic compounds biosynthesized in pink-colored skin of Japanese indigenous Vitis vinifera cv. Koshu grape

Kobayashi, Hironori,Suzuki, Yumiko,Ajimura, Kosei,Konno, Tomonori,Suzuki, Shunji,Saito, Hiroshi The Korean Society of Plant Biotechnology 2011 Plant biotechnology reports Vol.5 No.1

Vitis vinifera cv. Koshu is a traditional grape cultivar that has been grown for centuries in Japan. The Koshu grape has pink-colored skin and Koshu wines have slight astringency. We demonstrated for the first time the characterization of hydroxycinnamic acids, flavan-3-ols, and flavonoids in Koshu grape using high-performance liquid chromatography and liquid chromatography-mass spectrometry. The gross weight of phenolic compounds excluding anthocyanins and proanthocyanidins in Koshu grape at harvest was higher than those in Sauvignon Blanc, Chardonnay, and Merlot grapes. In addition, hydroxycinnamic acid and monomeric flavonol contents in Koshu grape were also higher than those in the other grape cultivars. Transcription analysis of cinnamic acid 4-hydroxylase, p-coumarate 3-hydroxylase, caffeate methyltransferase, and flavonol synthase genes indicated high accumulation of hydroxycinnamic acids and flavonols in Koshu grape skin compared with the other cultivars. These findings obtained by chemical and molecular approaches partially explained the phenolic characteristics and the peculiar astringency of Koshu grape.

Outcomes of ‘one-day trial of vaginal delivery of twins’ at 36–37 weeks’ gestation in Japan

Yuria Haruna,Shunji Suzuki 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.6

ObjectiveThe lack of obstetricians in Japan has prevented the implementation of a 24–hour delivery monitoring system forhigh-risk deliveries such as twin vaginal delivery at many obstetric facilities. To examine the outcomes of a 1-day trialof the vaginal delivery of twins at 36–37 weeks’ gestation. MethodsWe induced the vaginal delivery of twins at 36–37 weeks’ gestation of 256 women who provided consent betweenJanuary 2007 and December 2016 using the following protocol: 1) administration of 0.5 mg oral prostaglandin E2every 1 hour (maximum: 1.5 mg) in the morning; 2) intravenous administration of oxytocin and amniotomy in theafternoon; and 3) selection of caesarean delivery when vaginal delivery was not expected by evening. We examinedtheir perinatal outcomes in a chart review. ResultsThe completion rates of vaginal delivery in total, nulliparous, and multiparous women were 79%, 72%, and 84%,respectively. There were no cases of neonatal asphyxia. The total incidence of neonatal respiratory disorders was2.1%, but there were no cases of persistent pulmonary hypertension. The total incidence of postpartum hemorrhagerequiring transfusion was 2.7%. ConclusionThe 1-day planned vaginal delivery of twins at 36–37 weeks’ gestation appears valid and safe, and our findingssuggest that it can be an option for the delivery of twins.

Synergistic repellent activity of hot and cool thermal-sense compounds against two stored product insect pests

Kenji Shimomuraa,Nobuhiro Suzuki,Shunji Hattori 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.2

The repellent activities of one hot thermal-sense compound, vanillyl butyl ether (VBE), and two cool thermalsense compounds, menthoxypropanediol (MPD) and (−)-isopulegol (IPG), against two stored product insects, Tribolium confusum and Liposcelis bostrychophila, were investigated. Such thermal-sense compounds affect mammals through transient receptor potential (TRP) channels, and both types of agonists (VBE and menthol) exhibited mutually inhibitory effects on mammalian TRPV1 and TRPM8 channels. Each compound exhibited repellent activity against both T. confusum and L. bostrychophila in a dose-dependent manner. Furthermore, synergistic effects were observed between VBE and MPD or IPG. The composition of TRP channels is different between mammals and insects. These results suggest that the use of thermal-sense compounds might serve as an alternative to essential oils in stored products protection.

Molecular characterization of Japanese indigenous grape cultivar ‘Koshu’ (Vitis vinifera) leaf and berry skin during grape development

Hironori Kobayashi,Keiko Fujita,Shunji Suzuki,Tsutomu Takayanagi 한국식물생명공학회 2009 Plant biotechnology reports Vol.3 No.3

We investigated the transcriptional profiles of Japanese indigenous grape cultivar ‘Koshu’ (Vitis vinifera) leaf and berry skin during ripening. In leaf, 64 genes were abundantly transcribed at the end of ve´raison (14 weeks post-flowering), whereas the expression of 61 genes was upregulated at the end of ripening (20 weeks post-flowering). In berry skin, 67 genes were abundantly transcribed at the end of ve´raison, whereas the expression of 86 genes was upregulated at the end of ripening. Gene expression associated with biological processes was activated in both tissues at the end of ripening. The expression of genes associated with photosynthesis, sugar synthesis, anthocyanin synthesis, cinnamic acid synthesis, and amino acid metabolism was observed in leaf and berry skin during ripening, together with the accumulation of sugars, anthocyanins, cinnamic acids, and amino acids. Transcripts of AUX/IAA family proteins that repress the activities of auxin-induced proteins were expressed in berry skin at the end of ve´raison. Transcripts of genes related to the ubiquitin– proteasome system that degrades AUX/IAA family proteins were abundantly expressed in berry skin at the end of ripening, suggesting that the expansion of skin cells at ve´raison is suppressed by AUX/IAA family proteins, and that the ubiquitin–proteasome system induces the expansion of skin cells during ripening by degrading AUX/IAA family proteins. These transcriptional profiles, which provide new information on the characteristics of ‘Koshu’ grapevine during ripening, may explain the unique characteristics of ‘Koshu’ grape in comparison with those of European grapes used for winemaking, and may contribute to the improvement of ‘Koshu’ grape quality. We investigated the transcriptional profiles of Japanese indigenous grape cultivar ‘Koshu’ (Vitis vinifera) leaf and berry skin during ripening. In leaf, 64 genes were abundantly transcribed at the end of ve´raison (14 weeks post-flowering), whereas the expression of 61 genes was upregulated at the end of ripening (20 weeks post-flowering). In berry skin, 67 genes were abundantly transcribed at the end of ve´raison, whereas the expression of 86 genes was upregulated at the end of ripening. Gene expression associated with biological processes was activated in both tissues at the end of ripening. The expression of genes associated with photosynthesis, sugar synthesis, anthocyanin synthesis, cinnamic acid synthesis, and amino acid metabolism was observed in leaf and berry skin during ripening, together with the accumulation of sugars, anthocyanins, cinnamic acids, and amino acids. Transcripts of AUX/IAA family proteins that repress the activities of auxin-induced proteins were expressed in berry skin at the end of ve´raison. Transcripts of genes related to the ubiquitin– proteasome system that degrades AUX/IAA family proteins were abundantly expressed in berry skin at the end of ripening, suggesting that the expansion of skin cells at ve´raison is suppressed by AUX/IAA family proteins, and that the ubiquitin–proteasome system induces the expansion of skin cells during ripening by degrading AUX/IAA family proteins. These transcriptional profiles, which provide new information on the characteristics of ‘Koshu’ grapevine during ripening, may explain the unique characteristics of ‘Koshu’ grape in comparison with those of European grapes used for winemaking, and may contribute to the improvement of ‘Koshu’ grape quality.

Electro-Magneto-Thermo-Mechanical Properties of a SMA Plate and its Application to Adaptive Thermo-Flow Control

Toshiyuki Takagi,Junji Tani,Shunji Suzuki,Minoru Matsumoto 대한전자공학회 1995 대한전자공학회 워크샵 Vol.1995 No.-

Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Lumbar Spinal Degeneration Disease

Seiji Ohtori,Sumihisa Orita,Kazuyo Yamauchi,Yawara Eguchi,Nobuyasu Ochiai,Shunji Kishida,Kazuki Kuniyoshi,Yasuchika Aoki,Junichi Nakamura,Tetsuhiro Ishikawa,Masayuki Miyagi,Hiroto Kamoda,Miyako Suzuki 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.4

Purpose: Surgery for lumbar spinal degeneration disease is widely performed. While posterior decompression and fusion are popular, anterior lumbar interbody fusion (ALIF) is also used for treatment. Extreme lateral interbody fusion (XLIF) is commonly used for noninvasive ALIF; however, several complications, such as spinal nerve and psoas muscle injury, have been reported. In the current study, we examined the clinical efficacy and complications of oblique lateral interbody fusion (OLIF) for lumbar spinal degeneration disease. Materials and Methods: Thirty-five patients with degenerated spondylolisthesis, discogenic pain, and kyphoscoliosiswere examined. All patients underwent OLIF surgery (using a cage and bone graft from the iliac crest) with or without posterior decompression, without real-time electromyography monitoring. Posterior screws were used in all patients. Visualanalog scale (VAS) score and Oswestry Disability Index (ODI) were evaluated before and 6 months after surgery. Surgical complications were also evaluated. Results:Pain scores significantly improved after surgery, compared to those before surgery (p<0.05). There was no patient who underwent revision surgery. There was no spinal nerve, major vessel, peritoneal, or urinary injury. Few patients showed symptoms from psoas invasion. Conclusion: OLIF surgery produced good surgical results without any major complication.

Efficacy of Direct Injection of Etanercept into Knee Joints for Pain in Moderate and Severe Knee Osteoarthritis

Seiji Ohtori,Sumihisa Orita,Kazuyo Yamauchi,Yawara Eguchi,Nobuyasu Ochiai,Shunji Kishida,Kazuki Kuniyoshi,Yasuchika Aoki,Junichi Nakamura,Tetsuhiro Ishikawa,Masayuki Miyagi,Hiroto Kamoda,Miyako Suzuki 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.5

Purpose: Osteoarthritic (OA) pain is largely considered to be inflammatory pain. However, during the last stage of knee OA, sensorynerve fibers in the knee are shown to be significantly damaged when the subchondral bone junction is destroyed, and this can induce neuropathic pain. Several authors have reported that tumor necrosis factor-α (TNFα) in a knee joint plays a crucial role in pain modulation. The purpose of the current study was to evaluate the efficacy of etanercept, a TNFα inhibitor, for pain in knee OA. Materials and Methods: Thirty-nine patients with knee OA and a 2–4 Kellgren-Lawrence grading were evaluated in this prospectivestudy. Patients were divided into two groups; hyaluronic acid (HA) and etanercept injection. All patients received a single injectioninto the knee. Pain scores were evaluated before and 4 weeks after injection using a visual analogue scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and they were compared between the groups. Results: Before injection, VAS and WOMAC scores were not significantly different between the groups (p>0.05). Significant pain relief was found in the etanercept group at 1 and 2 weeks by VAS, and at 4 weeks by WOMAC score, compared with the HA group (p<0.05). No adverse events were observed in either group. Conclusion: Direct injection of etanercept into OA knee joints was an effective treatment for pain in moderate and severe OA patients. Furthermore, this finding suggests that TNFα is one factor that induces OA pain.