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      • 詩經正變設考

        金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-

        It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.

      • Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

        Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

      • KCI등재후보
      • KCI등재

        Hot Deformation Characteristics and Processing Map Analysis of Pre-Forged AZ80 Magnesium Alloy

        Shi‑quan Huang,Ming Lu,Sheng‑lan Luo,Hai‑lin He,You‑ping Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        The hot deformation behavior of pre-forged AZ80 magnesium alloy is investigated by the isothermal compression tests attemperatures of 523–683 K and strain rates of 0.0001–0.1 s−1, and analyzed by the processing maps for guiding isothermaldie forging. Flow localization and even cracking occurs at low temperatures and high strain rates, where shear deformationdegree shows a positive correlation with the ��( ̇�� ) value. Two stability regions with high efficiency is found out by theprocessing maps. At common stability region with high temperatures and low strain rates, peak power dissipation efficiencydoes not represent optimum deformation condition as reported in other materials. A Z parameter criterion is introduced forparameters optimization. javascript:void(0); a new stability domain of 523–590 K and 0.0001–0.01 s−1 is observed, which istypical for fine microstructure composed of equiaxed clean α-Mg grains and big particles both about 1 μm (573 K/0.01 s−1).Super plasticity is speculated to occur at that condition.

      • SCOPUSKCI등재
      • KCI등재
      • SCOPUSKCI등재

        유치원의 원예체험학습 현황분석에 관한 연구 : 천안시를 중심으로

        이시래,이경애,서정근 韓國植物ㆍ人間ㆍ環境學會 1999 인간식물환경학회지 Vol.2 No.4

        This study was conducted out analyze the status and several points of HES(Horticultural Experience Study) program in kindergarten. Most of kindergarten was not employed professional hort-educator. The teachers had little knowledge for HES. Most kindergartens taken lesson in program or picnic, inspection and regular class. The most of HES place was weekend farm, and the state of instrument condition not equipped. Used plant-material in HES was mainly simple material of vegetables such as sweet-potato, red-pepper, several flowers and fruits. One of the HES program was sowing, harvesting, cooking and flower decoration in classroom. The most children was generally satisfied with the HES program in outside kindergarten than inside. The effect of HES programs in children was natural fellowship, achievement after harvesting and environment education. The problems of HES curriculum were that the teachers were lack of knowledge in horticultural fields. Kindergarten don't have enough to study space and financial support. It was hoped that kindergartens should provide learning place near the kindergarten, much financial support from government, train professional hort-educator, development of systematic variable programs.

      • 方言에 있어서의 上聲考

        千時權 慶北大學校 1958 論文集 Vol.2 No.-

        As to the Bang-jum(蒡點) similar to four tones in Chinese character which we can find in the books printed 15th century, some scholars have been for a long time recognized that the side dots show long and short tone, however, recently some scholars, such as Dr. Lee Sung Nyung, Prof. Hue Ung and Japanese Kono Rokuro notices that this marks show pitch accent; one dot is Kuh-Sung(去聲), high; two dot is Sang-Sung(上聲), low-rising; none dot is Pyung-Sung(平聲), low. Though we can find out long and short tones in modern Korean Colloquial Standard words, but we can recognize pitch accent in some dialect. I intend to reaearch whether Sang-Sung which showed in written language appear in colloquial dialect or not. Because this Sang-Sung have been expressed in many types than the other tones. Today, this Sang-Sung is pronounced as low-long tone in central parts of Korea, as more low tone in South Kyungsan province, high in Hamkyung province, fore-low rear-high tone in some vocabulary in North Kyungsang province. Fundamentary, we can classify the Korean dialect into the two great parts. One is the districts, central parts of korea-Pyungan, Hwanghae, Kangwon which inherited Koryolang uage; the other one is the districts-Kyungsan, Chulla, Hamkyung which inherited Silla language. From this point of view, we can say that the San-Sung display more complicated phenomenon in the district which inherited Silla language. So the phenomenon such fore-low in Kyungnam, rear-high in Hamkyung have been displaing in todays dialect. The reasons are as following facts; (1) There are still fore-loe-rear-high tone in Kyungpook parts. (2) Hamkyung parts were cultivated by the southerner who were immigrated as shown in our history -vide the record of the geography Sechong Silrok. (3) The change of the language for the Imjin waeran (17c) etc. Therefore Sang-Sung the original fore-low-rear-high was all of them divided and developed except few words in Kyungpook parts. Low-long tone …… Seoul, Kyungki, Hwanghae, Pyungan, Chungcheung, Kangwon, Chulla, Kyungpook. Lower tone …… Kyungnam. High tome …… Hamkyung.

      • Furan의 2-치환체에 대한 conformation에 관한 연구

        金時俊,全容求 漢陽大學校敎養學部 1976 硏究論文集 Vol.- No.1

        2-formyl furan, 2-acetyl furan, chloro-2-furyl ketone의 conformation 에 관하여 擴張 Huckel 分子軌道法 計算을 실시하였다. 計算 結果는 conformation이 trans型인 것이 cis型 보다 더 安定하다. 이 安定化에너지의 대부분은 정전기적인 原子間의 힘에 기인하는 것임을 밝혔다. The conformation of 2-formyl furan, 2-acetyl furan and chloro-2-furyl ketone have been studied from extended Huckel molecular orbital calculations. The results show that the trans-conformation of the ?? bond is favored compared with that of cis-conformation, ?? The major part of the stabilization energies can be accounted for by the electrostatic energies between the atoms involved.

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