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Effect of Fading on Performance of VANET in Realistic Scenarios Using NCTUns6.0
Richa Sharma,Jyoteesh Malhotra,Komal Sharma 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.1
Road safety and increasing transport efficiency are the important goals for intelligent transport system (ITS). Vehicular Ad hoc Network is such a network which can help to achieve these goals. VANET routing is a crucial task for reliable communication among vehicles. The impact of fading on network throughput and packet drop is explored in this paper. Interesting results show the performance evaluation of without fading environment and Rayleigh fading in different scenarios. NCTUns 6.0 (National Chiao Tung University Network Simulator) is used to justify our results that is a GUI based open source platform for vehicular Ad-Hoc network. Various performance issues are also surveyed with the help of this simulator.
Komal SHARMA,Hyun Uk KIM 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10
Pyrrolobenzodiazepines are a class of natural products produced by actinomycetes, possessing antitumor properties, such as actinomycin D, sibiromycin and anthramycin. These antitumors are biosynthesized by complex modular enzymes called non-ribosomal peptide synthases with 3-hydroxy-4-methyl anthranilic acid (3-MHA) as a common intermediate in biosynthetic pathways. The biosynthetic pathway for 3-MHA was heterologously expressed and refactored in Escherichia coli BAP1 cells, which led to de novo biosynthesis of 3-MHA from L-tryptophan via kynurenine pathway. Different genes of actinomycin D and sibiromycin biosynthetic gene clusters were explored, and the best set of genes for the production of 3-MHA was established. The resulting E. coli strain capable of producing 3-MHA will serve as a platform strain for the enhanced production of pyrrolobenzo-diazepines.
Optical dating of late Quaternary carbonate sequences of Saurashtra, western India
Sharma, Komal,Bhatt, Nilesh,Shukla, Anil Dutt,Cheong, Dae-Kyo,Singhvi, Ashok Kumar Cambridge University Press 2017 Quaternary research Vol.87 No.1
<B>Abstract</B><P>Bioclastic carbonate deposits that formed because of a combination of nearshore marine, fluvial, and aeolian processes, occur along the Saurashtra coast and in the adjacent interior regions of western India. Whether these carbonates formed by marine or aeolian processes has been debated for many decades. The presence of these deposits inland poses questions as to whether they are climate controlled or attributable to postdepositional tectonic uplift. In particular, the debate centres on chronologic issues including (1) appropriate sampling strategies and (2) the use of <SUP>230</SUP>Th/<SUP>234</SUP>U and <SUP>14</SUP>C ages on the bulk carbonates. Using traces (<1%) of quartz grains trapped in carbonate matrices, optically stimulated luminescence (OSL) dating of quartz grains, deposited along with the carbonate grains, provides ages for the most recent deposition events. The OSL ages range from >165 to 44 ka for the shell limestones, 75-17 ka for the fluvially reworked sheet deposits, and 80-11 ka for miliolites deposited by aeolian processes. These are younger than the <SUP>230</SUP>Th/<SUP>234</SUP>U and <SUP>14</SUP>C ages and suggest that the inland carbonate deposits were reworked from older carbonate sediments that were transported during more arid phases.</P>
Kang Hee Yun,Komal Sharma,Hyun Uk Kim,Tae-Hyun Bae 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.123 No.-
Microfiltration membranes are increasingly used in sterilization processes in the pharmaceutical industry. However, in the pharmaceutical industry, product loss caused by the adsorption of high value-addedproteins to membranes during the sterilization process is a critical problem. Hence, it is necessary toreduce protein adsorption and fouling through the hydrophilic modification of the entire membrane,not just the surface. We developed a method for fabricating a porous poly(ethersulfone) (PES) microfiltrationmembrane using vapor-induced phase separation (VIPS) and then conducting hydrophilic modificationof the membrane. Two types of symmetric membranes with 0.2 lm pores were prepared usingtwo different additives, one of which was an amphiphilic copolymer (Pluronic PE6400) that is known toincrease the hydrophilicity of PES membranes. Both membranes had high water permeability and suitablemechanical strength. However, protein filtration testing, including an adsorption study, revealedthat the hydrophilicity imparted by Pluronic was not sufficient to effectively inhibit protein adhesion. In contrast, the modification via the atom transfer radical polymerization of a hydrophilic oligomer(poly(ethyleneglycol) methacrylate) significantly increased the hydrophilicity of the entire membranewhile reducing the surface roughness. These properties reduced protein adsorption and membrane fouling,to the benefit of sterile filtration and protein filtration processes.
Mohammad Rifqi GHIFFARY,Cindy Pricilia Surya PRABOWO,Komal SHARMA,Sang Yup LEE,Hyun Uk KIM 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10
Current industrial production of dyes for textiles mainly involves numerous toxic chemicals which causes severe water pollution. For this, indigoidine has attracted attention as an alternative natural blue dye, but it is necessary to achieve a high-level production to compete with existing synthetic blue dyes. Here, we report a metabolically engineered Corynebacterium glutamicum capable of producing indigoidine to a high concentration with high productivity. First, blue-pigment indigoidine synthetase (bpsA) gene from Streptomyces lavendulae was expressed in C. glutamicum, which already carries strong fluxes toward L-glutamate, a precursor of indigoidine. Production performance of this base strain, already producing 7.3 ± 0.3 g/L indigoidine from flask, was further improved through a series of metabolic engineering: streamlining intracellular supply of the precursors Lglutamate and L-glutamine; strengthening phosphotransferase system-independent glucose uptake system; channeling carbon fluxes from glycolysis to tricarboxylic acid (TCA) cycle; and minimizing byproducts formation. The final strain named BIRU11 produced 49.30 g/L indigoidine with the productivity of 0.96 g/L/h from fed-batch fermentation, the highest titer and productivity to date. Finally, indigoidine from the fed-batch fermentation of the BIRU11 strain was used to dye white cotton fabrics to examine its color and performance. This study demonstrates the potential of producing fabric dyes in a sustainable manner by using a metabolically engineered bacterium.