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RISS 인기검색어
- 검색키워드
- 저자 : Shahnaz Begum (검색결과 5 건)
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이미라,Shahnaz Begum,성창근 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.6
This study investigated the effects of chronic administration of red ginseng extract (RGE) and black ginseng extract (BGE) on memory impairment in aged (18- month-old) mice. RGE and BGE (200 mg/kg) were orally administered for 16 weeks. Aging induced DNA damage; however, RGE and BGE protected DNA from damage and allowed for DNA recovery in blood lymphocytes. Choline acetyltransferase, vesicular acetylcholine transporter, growth-associated protein 43, synaptosomal-associated protein 25, nerve growth factor, and brain-derived neurotrophic factor protein expression were significantly increased after treatment with RGE and BGE. These data suggest that chronic administration of red ginseng and black ginseng may decrease the cognitive deficits associated with normal aging.
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Ameliorating Effect of Mycoleptodonoides aitchisonii on High-fat Diet-induced Obese Mice
Lee, Mi Ra,Begum, Shahnaz,Oh, Deuk Sil,Wee, An Jin,Yun, Byung Sun,Sung, Chang Keun The Korean Society of Food Science and Nutrition 2014 Preventive Nutrition and Food Science Vol.19 No.2
The present study investigated the anti-obesity effects of Mycoleptodonoides aitchisonii (MA) in mice fed a high-fat (HF) diet. Two groups were fed either a normal control diet or an HF (45% kcal fat) diet for 12 weeks and three groups were fed an HF diet supplemented with powdered MA (MAP, 1%, 3%, and 5%) for 12 weeks. The anti-obesity effects of MAP supplementation on body weight, fat mass development, and lipid-related markers were assessed. Consumption of an HF diet resulted in increased body weight, serum lipids, relative adipose tissues weight, and liver fat accumulation. However, administration of MAP significantly decreased body weight gain, food intake, food efficiency ratio, hepatic cholesterol level, and adipose tissue weight in a dose-dependent manner. In addition, treatment with MAP significantly reduced the occurrence of fatty liver deposits and steatosis, and inhibited an HF diet-induced increase in adipocyte size. These results suggest that dietary supplementation with MAP exerts anti-obesity effects and indicate that MAP could be used as a functional food to control obesity.
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Ameliorating Effect of Mycoleptodonoides aitchisonii on High-fat Diet-induced Obese Mice
Mi Ra Lee,Shahnaz Begum,Deuk Sil Oh,An Jin Wee,Byung Sun Yun,Chang Keun Sung 한국식품영양과학회 2014 Preventive Nutrition and Food Science Vol.19 No.2
The present study investigated the anti-obesity effects of Mycoleptodonoides aitchisonii (MA) in mice fed a high-fat (HF) diet. Two groups were fed either a normal control diet or an HF (45% kcal fat) diet for 12 weeks and three groups were fed an HF diet supplemented with powdered MA (MAP, 1%, 3%, and 5%) for 12 weeks. The anti-obesity effects of MAP supplementation on body weight, fat mass development, and lipid-related markers were assessed. Consumption of an HF diet resulted in increased body weight, serum lipids, relative adipose tissues weight, and liver fat accumulation. However, administration of MAP significantly decreased body weight gain, food intake, food efficiency ratio, hepatic cholesterol level, and adipose tissue weight in a dose-dependent manner. In addition, treatment with MAP significantly reduced the occurrence of fatty liver deposits and steatosis, and inhibited an HF diet-induced increase in adipocyte size. These results suggest that dietary supplementation with MAP exerts anti-obesity effects and indicate that MAP could be used as a functional food to control obesity.
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이미라,Jing Gang Hou,Shahnaz Begum,Jian Jie Xue,Yun Bo Wang,성창근 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.6
This study evaluates three edible mushrooms:Lentinus edodes, Sparassis crispa, and Mycoleptodonoidesaitchisonii, in terms of acetylcholinesterase (AChE)inhibition, antioxidant potency and constituents free aminoacids and mineral. The concentration of essential aminoacids was found to be 34.10 mg/g in M. aitchisonii, 26.25mg/g in S. crispa, 25.99 mg/g in L. edodes. S. crispadisplayed the highest DPPH scavenging activity andphenolic contents. The best results for AChE inhibitionwere obtained from M. aitchisonii. These results suggestthat M. aitchisonii has high potential for cognitiveimprovement by AChE inhibition and antioxidant potency.
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Anti-obesity Effects of Sparassis crispa on High-fat Diet-induced Obese Mice
Mi Ra Lee(이미라),Jing Gang Hou(하지강),Shahnaz Begum(샤나즈베검),Yun Bo Wang(왕운보),Deuk Sil Oh(오득실),An Jin Wi(위안진),Byung Sun Yoon(윤병선),Chang Keun Sung(성창근) 한국생명과학회 2014 생명과학회지 Vol.24 No.9
본 연구는 고지방식이로 유도한 비만 흰쥐에 대한 꽃송이 버섯의 항비만 효과를 관찰하였다. 6주령 수컷C57BL/6 마우스를 이용하여 칼로리의 45%를 지방으로 구성한 고지방식이를 이용하여 비만을 유도하였으며, 대조군은 정상식이를 제공하였다. 처리군은 고지방 식이에 꽃송이 버섯 분말을 1%, 3%, 5% 수준으로 첨가하여 12주간 제공하였다. 체중, 식이섭취, 장기무게, 내장지방, 혈청지질, 변무게 및 변지방, 간지방, 조직병리실험을 실시하였다. 고지방식이 섭취군은 체중, 식이섭취, 피하지방 및 복막하지방, 혈청 콜레스테롤 및 중성지방농도, 변지방, 간지방, 부고환지방 조직의 지방세포 크기가 증가하였다. 그러나 고지방식이에 꽃송이 버섯 분말을 첨가한 실험군에서는 체중증가, 식이섭취 및 식이효율, 간 콜레스테롤 함량, 내장지방 무게가 꽃송이 버섯 첨가량에 따라 감소하였다. 특히, 5% 꽃송이버섯 첨가군은 간세포의 지방축적과 지방간 현상이 현저히 개선되었으며, 부고환 지방조직에서의 지방세포 크기도 현저히 감소하였다. 본 연구결과를 통하여 볼 때, 꽃송이 버섯은 뛰어난 항비만 효과를 가지고 있어, 비만 조절을 위한 기능성 식품으로의 이용이 가능할 것으로 사료된다. The present study investigated the anti-obesity effects of Sparassis crispa (SC) on mice fed a high-fat (HF, 45 kcal% fat) diet. Mice were fed either a normal control diet and an HF diet or an HF diet supplemented with SC (1%, 3%, and 5%) for 12 weeks. The consumption of an HF diet compared to the NC group resulted in increases in body weight, the food efficiency ratio (FER), retroperitoneal and subcutaneous fat weights, cholesterol and triglyceride levels, fecal fat, and liver lipids. However, the administration of SC significantly decreased body weight gain, food intake, FER, cholesterol and triglyceride levels, and liver lipids in a dose-dependent manner. In particular, treatment with 5% SC significantly reduced the occurrence of fatty liver deposits and steatosis, which are associated with the increased adipocyte size in mice fed an HF diet. Therefore, these results suggested that dietary supplementation with SC exerts anti-obesity effects and could be used as a functional food to control obesity.
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