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흉막삼출액에서 높은 Adenosine Deaminase 활성도를 보인 마이코플라즈마 폐렴
서향은 ( Seo Hyang Eun ),김연재 ( Kim Yeon Jae ),김성규 ( Kim Seong Gyu ),강현재 ( Kang Hyeon Jae ),도윤경 ( Do Yun Gyeong ),윤혜진 ( Yun Hye Jin ),전재현 ( Jeon Jae Hyeon ),이병기 ( Lee Byeong Gi ),김원호 ( Kim Won Ho ) 대한결핵 및 호흡기학회 2002 Tuberculosis and Respiratory Diseases Vol.52 No.1
태아발육지연이 과기임신의 높은 주산기 사망률에 미치는 영향
서경 ( Seo Gyeong ),원형재 ( Won Hyeong Jae ),조재성 ( Jo Jae Seong ),박용원 ( Park Yong Won ),김세광 ( Kim Se Gwang ),이국 ( Lee Gug ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.10
목적 : 정상체중아와 태아발육지연의 만삭 및 과기임신에서 주산기사망율의 증가 양상을 분석하여 태아발육지연이 과기임신의 주산기 사망률 증가에 기여하는 영향을 분석하고자 한다. 연구 방법 : 1961년부터 1990년까지 연세대학교 의과대학 세브란스병원에 내원하여 단태아를 분만한 임산부 51,177명 중 제태연령이 확실하고 산과적 및 내외과적 합병을 제외한 임산부로서 선천성기형을 제외한 임신 37주에서 44주까지의 임산부 및 출생아 39,751명을 대상으로 Objective : Perinatal mortality rates were higher in postdate than in term pregnancies. Previous study showed the risk to be greater in postterm newborns weighing less than 2500 grams at birth. This study is designed to examine the effect of gestational a
Park, Gyeong-Jae,Son, Byungkwan,Seo, SangHyeok,Lee, Ji-Han,Kim, Yong-Jae,Jung, Sang-Yong IEEE 2018 IEEE transactions on magnetics Vol.54 No.3
<P>Numerical analysis in frequency-domain guarantees convincing accuracy by reflecting non-linearity of material without massive computation time, combining advantages of the equivalent circuit method and numerical analysis method. However, at highly magnetic saturated regions where non-linearity of the material is severe, error in torque calculation is evident, as parameters in frequency domain are presumed to be in a sinusoidal condition. Many researchers have been suggested a compensating method by creating fictious material with logically modified <TEX>$B$</TEX>– <TEX>$H$</TEX> curve. Nevertheless, the error between the results of the numerical analysis in frequency-domain and time-domain analysis is not small enough to estimate motor characteristic. Therefore, the compensation method for improving accuracy on the estimation of induction motor characteristics is proposed in this paper. The numerical analysis based on finite-element method in frequency domain has been conducted using the proposed fictious material and the result is compared to those of the conventional methods and time-domain analysis to validate its improvement on accuracy.</P>
대간간학회지 제6차 춘계학술대회 초록집 : 구연 ; 원발성 답즙성 간경변증의 임상 및 병리학적 고찰
서경덕 ( Seo Gyeong Deog ),이재승 ( Lee Jae Seung ),이창훈 ( Lee Chang Hun ),송경하 ( Song Gyeong Ha ),이종훈 ( Lee Jong Hun ),이성욱 ( Lee Seong Ug ),신우원 ( Sin U Won ),박희승 ( Park Hui Seung ),강대환 ( Kang Dae Hwan ),송근암 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.1(S)
중증 지역사회획득 폐렴환자의 예후에 영향을 미치는 면역지표에 대한 연구
황재경 ( Hwang Jae Gyeong ),이호명 ( Lee Ho Myeong ),서일혜 ( Seo Il Hye ),남귀현 ( Nam Gwi Hyeon ),송광식 ( Song Gwang Sig ),박계영 ( Park Gye Yeong ),박정웅 ( Park Jeong Ung ),박재경 ( Park Jae Gyeong ),정성환 ( Jeong Seong H 대한결핵 및 호흡기학회 2001 Tuberculosis and Respiratory Diseases Vol.50 No.4
Lee, Myoung-Jae,Park, Gyeong-Su,Seo, David H.,Kwon, Sung Min,Lee, Hyeon-Jun,Kim, June-Seo,Jung, MinKyung,You, Chun-Yeol,Lee, Hyangsook,Kim, Hee-Goo,Pang, Su-Been,Seo, Sunae,Hwang, Hyunsang,Park, Sung American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.35
<P>Transition metal oxide-based memristors have widely been proposed for applications toward artificial synapses. In general, memristors have two or more electrically switchable stable resistance states that device researchers see as an analogue to the ion channels found in biological synapses. The mechanism behind resistive switching in metal oxides has been divided into electrochemical metallization models and valence change models. The stability of the resistance states in the memristor vary widely depending on: oxide material, electrode material, deposition conditions, film thickness, and programming conditions. So far, it has been extremely challenging to obtain reliable memristors with more than two stable multivalued states along with endurances greater than ∼1000 cycles for each of those states. Using an oxygen plasma-assisted sputter deposition method of noble metal electrodes, we found that the metal-oxide interface could be deposited with substantially lower interface roughness observable at the nanometer scale. This markedly improved device reliability and function, allowing for a demonstration of memristors with four completely distinct levels from ∼6 × 10<SUP>-6</SUP> to ∼4 × 10<SUP>-8</SUP> S that were tested up to 10<SUP>4</SUP> cycles per level. Furthermore through a unique in situ transmission electron microscopy study, we were able to verify a redox reaction-type model to be dominant in our samples, leading to the higher degree of electrical state controllability. For solid-state synapse applications, the improvements to electrical properties will lead to simple device structures, with an overall power and area reduction of at least 1000 times when compared to SRAM.</P> [FIG OMISSION]</BR>
Site-specific Methylation of Epigallocatechin Gallate (EGCG) by Bacterial O-methyltransferas
Gyeong-Guk PARK,Heewon NHO,Uk-Jae LEE,Joo-Hyun SEO,Byung-Gee KIM 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10
Green tea is well known for its various biological activities. It has been widely consumed as beverages and medicine in East Asia. The global green tea market is growing rapidly as consumer`s awareness of the efficacy of the Epigallocatechin-3-gallate (EGCG). EGCG, the main active ingredient catechin in green tea, shows health effects including potent antioxidant, anti-inflammatory, and anti-cancer. The bioavailability of EGCG by oral administration is relatively low related to its poor membrane permeability and stability in the gastrointestinal tract and blood. So structural modification was needed to improve the effect of oral EGCG. The methylated EGCG is the solution to overcome physiological disadvantages. It was reported that the oral absorption rate of EGCG’’3Me was significantly increased. Furthermore, its therapeutic effect against high blood pressure was also improved. And focused on the active site of the enzyme, we selected key residues by multiple sequence alignment and alanine scanning. The following work is to complete the site saturation mutagenesis and confirm the activity enhancement.