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      • KCI등재

        Electrochemical and Spectroscopic Study on the Corrosion of Ti–5Al and Ti–5Al–5Cu in Chloride Solutions

        ElSayed M. Sherif,Fahamsyah H. Latief,Hany S. Abdo,Nabeel H. Alharthi 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.6

        In this study, manufacturing of Ti–5Al and Ti–5Al–5Cu alloys were accomplished employing mechanical alloying technique. The corrosion resistance in 3.5 wt% NaCl solution of Ti–5Al and Ti–5Al–5Cu alloys was investigated using cyclicpolarization (CPP), electrochemical impedance spectroscopy (EIS) and chronoamperometric current–time measurements. The corroded surfaces of Ti–5Al and Ti–5Al–5Cu were examined by the use of a scanning electron microscopy and energydispersive X-ray spectroscopy. It is found that Ti–5Al suffers both uniform and pitting corrosion, particularly with prolongingthe time of exposure period in the chloride solution. While, the addition of Cu, Ti–5Al–5Cu alloy, increases the intensity ofuniform corrosion and decreases the probability of pitting attack. Prolonging the immersion time to 48 h before measurementdecreases the corrosion of Ti–5Al alloy, while increases the corrosion of Ti–5Al–5Cu.

      • KCI등재

        Alleviation of salt stress in  Triticum aestivum by biopriming with  Phanerochaete chrysosporium

        Hanan El-Sayed Dief,El-Sayed A. Hashem,Salwa Fawzan,Ashraf S. A. El-Sayed 한국작물학회 2021 Journal of crop science and biotechnology Vol.24 No.1

        Wheat is one of the most important cereals, vital basic crop in Egypt, covering approximately 32.6% of the total winter land. However, sensitivity to abiotic stress especially salinity is one the major current hurdles that reduce the global yield of this crop. Plant biopriming with fungi is the recent technology that might alleviate the salt stress eff ect. Thus, the objective of this work was to examine the eff ect of Triticum aestivum grains biopriming with Phanerochaete chrysosporium on the response of wheat to salt stress. From the physiological and biochemical parameters, biopriming of wheat grains with P. chrysosporium significantly alleviates the salt stress and markedly increases the growth parameters, photosynthetic pigments and osmolytes (soluble sugars, soluble protein and proline) contents. In addition, it alleviates the oxidative damage, as indicated by the lower accumulation of malondealdehyde and increasing the activity of antioxidant enzymes; superoxide dismutase, catalase, and ascorbate peroxidase in wheat seedlings. Results indicate the potential of using P. chrysosporium biopriming for reducing the deteriorating eff ects of salinity.

      • KCI등재후보

        Bisphosphonate’s effect on the tongue in adult male albino rats and the possible protective role of rutin: light and scanning electron microscopic study

        Dalia El-sayed El-ghazouly(Dalia El-sayed El-ghazouly ),Rania Ibrahim Yassien(Rania Ibrahim Yassien ) 대한해부학회 2024 Anatomy & Cell Biology Vol.57 No.1

        Alendronate sodium (ALS) is a nitrogen-containing bisphosphonate used for the treatment of different bone disorders. However, its adverse effect on oral soft tissue has been detected. Rutin (RUT) is natural flavonoid with antioxidant and anti-inflammatory properties. This work aimed to investigate the possible effect of ALS on the tongue of adult male albino rats and to evaluate the possible protective role of RUT. Forty adult male albino rats were equally divided into four groups: group I (control), group II (RUT): Received RUT 50 mg/kg, group III (ALS): Received ALS 1 mg/kg, group IV (ALS+RUT): Received ALS and RUT with the same doses as pervious groups. The drugs were given once daily for 5 weeks. Tongue specimens were taken and processed for light and scanning electron microscopic inspection. ALS treated group revealed structural changes in the tongue in the form of decrease in the height of the filiform papillae with blunt ends, marked atrophy in some papillae with areas of focal loss, loss of some epithelial cells, pyknotic nuclei and cytoplasmic vacuoles in some epithelial cells. The lamina propria showed inflammatory cellular infiltration with congested blood vessels. Statistically, there were highly significant decrease in the number of proliferating cell nuclear antigen immunopositive cells, area percentage of Bcl-2 immunoexpression and highly significant increase in the collagen content compared to control group. Administration of RUT with ALS minimizes these changes. RUT protected the rat tongue against the histological and immunohistochemical changes induced by ALS through its antioxidant and anti-inflammatory properties.

      • Memory response in elasto-thermoelectric spherical cavity

        El-Attar, Sayed I.,Hendy, Mohamed H.,Ezzat, Magdy A. Techno-Press 2020 Coupled systems mechanics Vol.9 No.4

        A mathematical model of electro-thermoelasticity subjected to memory-dependent derivative (MDD) heat conduction law is applied to a one-dimensional problem of a thermoelectric spherical cavity exposed to a warm stun that is an element of time in the presence of a uniform magnetic field. Utilizing Laplace transform as an instrument, the issue has been fathomed logically within the changed space. Numerical inversion of the Laplace transform is carried for the considered distributions and represented graphically. Some comparisons are shown in the figures to estimate the effects of MDD parameters and thermoelectric properties on the behavior of all considered fields.

      • KCI등재

        Syzygium aromaticum L.: phytochemical investigation and comparison of the scavenging activity of essential oil, extracts and eugenol

        El Ghallab Yassine,Al Jahid Abdellah,Jamal Eddine Jamal,Ait Haj Said Amal,Zarayby Lhoussaine,Derfoufi Sanae 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.2

        Syzygium aromaticum L. is a popular flavor and fragrance spice used in cooking, traditional and modern therapy. No work has compared between the scavenging capacity of the essential oil, extracts and eugenol, or studied that of the hexane extract, as well as its phenolic and flavonoid contents. To reveal more details on phytochemical and scavenging characteristics of Syzygium aromaticum spice, we estimated the scavenging activity of the essential oil, each extract of water, ethanol, ethyl acetate and hexane obtained from clove buds, based on their effective concentration able to scavenge 50% (EC50) of 2,2′-diphenyl-1-picrylhydrazyl, and 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt free radicals. The essential oil showed high scavenging activity (EC50 of 0.40 ± 0.06 and 0.42 ± 0.02 mg/ml), and comprises 13 identified compounds. Eugenol, β-Caryophyllene, eugenyl acetate and α-Humulene are the major components. Comparing extracts, those of ethanol and hexane exhibited the greatest phenolic content (351.83 ± 17.90 and 348.04 ± 24.54 mg of gallic acid equivalent/gextract respectively) and the potent scavenging activities (EC50 of 0.41 ± 0.03 and 0.37 ± 0.00 mg/ml respectively). A moderate flavonoid content was observed, and aqueous extract was the best (21.90 ± 0.16 mg of quercetin equivalent/gextract). According to thin layer chromatography screening, all extracts content eugenol except that of water, this phenol contributes mainly on the scavenging activity and seems to be more active in mixture with terpenes, like in essential oil.

      • SCOPUSKCI등재

        Syntheses of 3-Pyrimidyl- and 3-Pyranyl-5,6-benzocoumarin Derivatives

        El-Deen, Ibrahim M.,Al-Wakeel, El-Sayed I.,El-Mawla, Ahmed G. Korean Chemical Society 2002 Bulletin of the Korean Chemical Society Vol.23 No.4

        A competitive enzyme-linked immunosorbent assay (ELISA) was developed for the quantitative detection of organophosphorus insecticide cyanophos. An analogue (hapten) of cyanophos was synthesized and was coupled to BSA to produce polyclonal antibodi es from rabbits. The antisera were screened against another hapten coupled to ovalbumin (OVA). Using the sera of highest specificity, an antigen-coated ELISA was developed, which showed an I50 of 310 ng/mL with the detection limit of 20 ng/mL. The antibodies showed negligible cross-reactivities with other organophosphorus pesticides except for parathion-methyl, which makes the assay suitable for the selective detection of cyanophos.

      • Nanostructured surfaces for analysis of anticancer drug and cell diagnosis based on electrochemical and SERS tools

        El-Said Waleed A.,Yoon Jinho,최정우 나노기술연구협의회 2018 Nano Convergence Vol.5 No.11

        Discovering new anticancer drugs and screening their efficacy requires a huge amount of resources and time-consuming processes. The development of fast, sensitive, and nondestructive methods for the in vitro and in vivo detection of anticancer drugs’ effects and action mechanisms have been done to reduce the time and resources required to discover new anticancer drugs. For the in vitro and in vivo detection of the efficiency, distribution, and action mechanism of anticancer drugs, the applications of electrochemical techniques such as electrochemical cell chips and optical techniques such as surface-enhanced Raman spectroscopy (SERS) have been developed based on the nanostructured surface. Research focused on electrochemical cell chips and the SERS technique have been reviewed here; electrochemical cell chips based on nanostructured surfaces have been developed for the in vitro detection of cell viability and the evaluation of the effects of anticancer drugs, which showed the high capability to evaluate the cytotoxic effects of several chemicals at low concentrations. SERS technique based on the nanostructured surface have been used as label-free, simple, and nondestructive techniques for the in vitro and in vivo monitoring of the distribution, mechanism, and metabolism of different anticancer drugs at the cellular level. The use of electrochemical cell chips and the SERS technique based on the nanostructured surface should be good tools to detect the effects and action mechanisms of anticancer drugs.

      • SCOPUSKCI등재
      • A controlled destruction and progressive collapse of 2D reinforced concrete frames

        El houcine, Mourid,Said, Mamouri,Adnan, Ibrahimbegovic Techno-Press 2018 Coupled systems mechanics Vol.7 No.2

        A successful methodology for modelling controlled destruction and progressive collapse of 2D reinforced concrete frames is presented in this paper. The strategy is subdivided into several aspects including the failure mechanism creation, and dynamic motion in failure represented with multibody system (MBS) simulation that are used to jointly capture controlled demolition. First phase employs linear elasto-plastic analysis with isotropic hardening along with softening plastic hinge concept to investigate the complete failure of structure, leading to creation of final failure mechanism that behaves like MBS. Second phase deals with simulation and control of the progressive collapse of the structure up to total demolition, using the nonlinear dynamic analysis, with conserving/decaying energy scheme which is performed on MBS. The contact between structure and ground is also considered in simulation of collapse process. The efficiency of the proposed methodology is proved with several numerical examples including six story reinforced concrete frame structures.

      • KCI등재

        In-vitro release and in-vivo performance of tolmetin from different topical gel formulations

        Sayed Hassan Auda,Saleh Abd El-Rasoul,Mahmoud Mohamed Ahmed,Shaaban Khalaf Osman,Mahmoud El-Badry 한국약제학회 2015 Journal of Pharmaceutical Investigation Vol.45 No.3

        This study was designed to evaluate the suitability of Pluronic F-127, different grades of Carbopol and cellulosic polymers as gel bases containing tolmetin, a nonsteroidal anti-inflammatory drug. In vitro release characteristics, effect of enhancers, viscosity and the mechanism of drug release for different gel bases was studied as well as the anti-inflammatory activity were evaluated. The results showed that the HPMC gel has the superior percent of drug release than the others. The percent released of drug from Carbopol and the Pluronic F-127 gels is concentration defendants. It was found that the drug release from the tested gel bases obeyed the diffusion mechanism. The use of propylene glycol and urea in different concentrations (3.0, 5.0 and 10 % w/v) had enhanced the percent of drug release significantly (p<0.05). The anti-inflammatory activity of the drug in Carbopol gel formulation showed excellent anti-inflammatory activity. These finding highlight the potential local application of tolmetin gel as topical anti-inflammatory medication.

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