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루이스 칸의 후기주택작품에서 ‘방’에 드러나는 거주의미 연구
오상은(Oh, Sang?Eun) 대한건축학회 2017 대한건축학회논문집 Vol.33 No.10
The purpose of this study is to analyze on the meaning of dwelling in ‘Room’ of Louis I. Kahn’s Architecture. ‘Room’ is generated by a realization of the nature of space. Nature of all kinds of an institution is in human’s dwell. The characteristics of dwelling analyzed from the ‘Room’ sketch, printed 1971 and his words unfold the senses of dwelling, which is the authenticity of architecture. These features are also linked analyzed with Louis I. Kahn’s three house projects, Esherick House, Fisher House, and Korman House. The phenomenal way acts this study. ‘Room’s is generated showing three characteristics, which are relational relativeness by territory between room and society of rooms, twin phenomena of inside and outside, and availability expressing of one’s self.
자가면역 췌장염의 동반증상 없이 발생한 IgG4 연관 경화성 담관염
천송욱 ( Song Wook Chun ),최자성 ( Ja Sung Choi ),강버들 ( Beo Deul Kang ),김유진 ( Yu Jin Kim ),한기준 ( Ki Jun Han ),조현근 ( Hyeon Geun Cho ),오화은 ( Hwa Eun Oh1 ),조재희 ( Jae Hee Cho ) 대한소화기학회 2013 대한소화기학회지 Vol.62 No.1
IgG4-related systemic diseases are characterized by a diffuse or mass forming inflammatory reaction rich in lymphocytes and IgG4-positive plasma cells (lymphoplasmacytic infiltration), fibrosclerosis of variable organs and obliterative phlebitis. They usually involve various organs including the pancreas, bile duct, gallbladder, salivary gland, retroperitoneum, kidney, lung, and prostate. However, most of them are accompanied by autoimmune pancreatitis, and good response to steroid treatment is one of the hallmarks of this disease. We report a case of an 67-year-old man with IgG4 associated sclerosing cholangitis, who was diagnosed by endoscopic retrograde cholangiopancreatography and successfully treated with steroid therapy. (Korean J Gastroenterol 2013; 62:69-74)
Yum, Woo Sung,Jeong, Yeonung,Song, Heamin,Oh, Jae Eun Elsevier 2018 Construction and Building Materials Vol.185 No.-
<P><B>Abstract</B></P> <P>This study explored the possibility of using limestone fines (LF) as a supplementary material in activated slag binder systems using two types of activators (i.e., 10 wt% of Ca(OH)<SUB>2</SUB> or 10 wt% of Ba(OH)<SUB>2</SUB>) and investigated the interactions of the activators with LF in each binder system through strength testing, powder X-ray diffraction, thermogravimetry, and mercury intrusion porosimetry. Using these binders, concrete brick samples containing LF were also made and examined for possible industrial applications. Although the influences of the LF addition on the strength, dissolution degree of the slag, reaction products, and pore-size distribution depended on the type and dosage of the activator, the addition was generally advantageous for all these aspects in both types of activations. The concrete brick made of 20 wt% LF using the Ba(OH)<SUB>2</SUB> activation fulfilled the Korean standard requirements of strength and water absorption for concrete bricks, and it also satisfied the criteria of the leaching test for possible toxic elements.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Limestone fines (LF) was studied as a supplementary material in activated slags. </LI> <LI> Main activators for slag were Ca(OH)<SUB>2</SUB> or Ba(OH)<SUB>2</SUB>. </LI> <LI> At early ages, the use of LF significantly improved strength in both activations. </LI> <LI> The use of LF significantly changed reaction products of Ba(OH)<SUB>2</SUB> activation. </LI> <LI> However, the use LF did not alter reaction products of Ca(OH)<SUB>2</SUB> activation. </LI> </UL> </P>
만성 콩팥병 환자에서 추정 사구체 여과율에 따른 25-Hydroxyvitamin D의 특성
고정희 ( Jung Hee Koh ),곽임수 ( Ihm Soo Kwak ),송상헌 ( Sang Heon Song ),이수봉 ( Soo Bong Lee ),이하린 ( Harin Rhee ),성은영 ( Eun Young Seong ),박창준 ( Chang Jun Park ),김태균 ( Tae Kyun Kim ),오상보 ( Sang Bo Oh ) 대한내과학회 2012 대한내과학회지 Vol.83 No.6
Background/Aims: Accumulating data suggest that vitamin D deficiency is prevalent in patients with chronic kidney disease (CKD). However, comprehensive data are lacking for Koreans. The aim of this study was to survey vitamin D deficiency among patients with CKD in Korea and to identify the relationships among various factors. Methods: We conducted a retrospective cohort study of 444 patients who were divided into four subgroups by estimated glomerular filtration rate (eGFR) for comparisons of mean 25-hydroxyvitamin D [25(OH)D] level and other parameters. In addition, non-dialyzed patients were categorized into four groups based on 25(OH)D levels (<10, 10-19, 20-29, and ≥ 30 ng/mL), and risk factors for severe vitamin D deficiency (<10 ng/mL) were investigated. Results: Of patients with an eGFR ≥ 60 mL/min/1.73 m2, 43% (34/79) showed severe 25(OH)D deficiency, and the mean 25(OH)D level was 11.7±5.3 ng/mL. In CKD3 group, 53.2% (41/77) showed severe 25(OH)D deficiency, with a mean level of 11.3±7.2 ng/mL. In CKD4 group, 53.3% (49/92) had severe 25(OH)D deficiency, with a mean level of 11.0±6.2 ng/mL. Approximately 71% (139/196) of patients in CKD5 group showed severe deficiency, and the mean level was 9.2±5.9 ng/mL. Severe 25(OH)D deficiency was affected by winter season, renal function, diabetes, and low-density lipoprotein cholesterol. The serum parathyroid hormone level was inversely correlated with the 25(OH)D level, such that 25(OH)D < 20 ng/mL were associated with a steep increase in parathyroid hormone. Conclusions: Vitamin D deficiency is highly prevalent in the Korean population. Few patients met a sufficient 25(OH)D concentration, even in the early stages of CKD. Our data suggest that 25(OH)D level of 20 ng/mL is a threshold for a rapid increase in parathyroid hormone levels. (Korean J Med 2012;83:740-751)
Diagnosis of Intestinal Tuberculosis by Polymerase Chain Reaction
Oh, Hwa Eun,Cho, Hyun Deuk,Choi, Jong Sang 고려대학교 의과대학 1998 고려대 의대 잡지 Vol.35 No.3
장결핵이 의심되는 42예의 생검 혹은 절제된 조직에서 PCR과 AFB 염색, 그리고 Rhodamine-Auramine 형광 염색(RAF-AFB)을 시행했다 환자는 만성 설사와 복통을 호소하였고 복통이 가장 흔한 증상이었다(76%). 병리학적 소견상, 10예에서 만성 건락성 육아종성염증으로 진단되었고. 32예는 만성 비건락성 육아종성 염증으로 진단되었다. Ziehl-Neelsen(ZN) AFB 염색에서 25예 중 11예에서 결핵균이 관찰되었으며(44%) Rhodamine-Auramine 형광 염색에서는 25예 중 13예에서 결핵균이 관찰되었다(52%). 25예 중 9예에서 Ziehl-Neelsen(ZN) AFB염색과 RAF-AFB 염색 모두에서 결핵균이 관찰되었으며. 6예는 두 AFB 염색중 어느 하나에서 결핵균을 관찰할 수 있었으므로 15예에서 결핵균을 관찰할 수 있었다(60%). PCR에서 전체 42예 중 8예에서 결핵균의 DNA를 확인할 수 있었다(19%). 비록 PCR이 장결핵의 진단에 있어서 빠르고, 민감한 방법이기는 하나, 우리의 실험결과에 의하면 상대적으로 덜 민감한 방법이었다. 그러므로, 결핵균을 검출하는데 있어서 AFB 염색과 PCR을 병행하는 것이 진단의 정확도를 높일 수 있으리라 생각한다. With 42 endoscopically biopsied or resected tissues, we performed a polymerase chain reaction(PCR), acid fast bacilli(AFB) stain assay and Rhodamine-Auramine fluorescent acid-fast (RAF-AFB) staining. With clinical impressions of intestinal tuberculosis, specimens were obtained from patients with chronic diarrhea or abdominal pain. Abdominal pain was the most common symptom (76%). On pathologic findings, ten of forty-two cases were diagnosed as chronic caseating granulomatous inflammation and thirty-two cases were diagnosed as chronic noncaseating granulomatous inflammation. Ziehl-Neelsen(ZN) stain from formalin-fixed, paraffin-embedded tissue revealed AFB in eleven of twenty-five cases(44%). Rhodamine-Auramine fluorescent acid-fast staining revealed AFB in thirteen of 25 cases(52%). Nine of 25 cases showed AFB on both ZN and RAF-AFB stainings and six of 25 cases showed AFB one each of ZN and RAF-AFB stainings, the resulting fifteen of 25 cases(60%) showed AFB with special stains. M. tuberculosis DNA was identified in 8 of 42 cases(l9%) by PCR, two cases of the positive eight cases and six cases without AFB stainings revealed positive findings on Tb-PCR. Although PCR is known a s a rapid, sensitive, and specific method for the diagnosis of intestinal tuberculosis, our study showed relatively low sensitivity and specificity, which might be caused by low numbers of organisms in the specimen and/or inadequate specimen. Therefore, for the detection of M. tuberculosis, diagnostic accuracy will be increased when both AFB stain and PCR are determined.