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Dynamic behavior of lifting pipe with equivalent model under mining vessel heave motion
QingHui Song,HaiYan Jiang,QingJun Song,Linjing Xiao,FangPing Yan 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.5
The lifting pipe is a key component of deep sea mining whose dynamic response directly affects the safety of the lift-ing operation. The objective of this paper was to investigate the effects of heave motion and sailing velocity of mining vessel and the buffer mass on the dynamic response of lifting pipe. First, an equivalent model of the lifting pipe was established, and the natural frequency and dynamic response of the lifting pipe equivalent model were determined with consideration of the wave action by the method of separated variables. Secondly, the reliability of the equivalent model was verified by simulating a 5000 m stepped pipe with OrcaFlex software. Then the dynamic displacement, axial tension, axial stress of the lifting pipe under different sea conditions and sailing velocities were studied, and the main factors affecting the dynamic response of the pipe described. By comparing the simulation results of actual and equivalent models, the equivalent model can be used to analyze the longitudinal vibration characteristics of the lifting pipe. The sailing velocity of the mining vessel has little effect on the dynamic response of the lifting pipe, but the surface wave has a significant effect.
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Analysis and Research of Magnetorheological Elastomers Piezoresistive Conductivity
Qiang Liu,Linjing Xiao,Qinghui Song,Yamin Fan 한국자기학회 2018 Journal of Magnetics Vol.23 No.3
On the basis of particle structure analysis, this paper studies the conductive mechanism of magnetorheological elastomers (MRE), and verifies the MRE conduction mechanism model based on the combination of tunnel current and conduction current. The piezoelectric characteristic of MRE is analyzed theoretically and the basic theoretical model of piezoelectric is established. A set of MRE piezoelectric characteristic test device has been designed independently. The test device is used to test the resistance values of MRE samples prepared in this experiment. Finally, the test results of each group are analyzed and compared, and the results show that this element can realize the stability test of MRE piezoelectric conductivity. Under different orders of magnitude, the low particle volume content is more sensitive to the conductivity of MRE samples, and the current flowing through the MRE sample shows a significantly non-linear relationship with the voltage applied to the sample.
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Xiaoyu Li,Xianzhi Zhao,Wen Song,Zibin Tian,Lin Yang,Qinghui Niu,Qi Zhang,Man Xie,Bin Zhou,Yonghong Xu,Jun Wu,Cuiping Zhang 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.1
Purpose: This study was aimed to investigate the effect of pseudolaric acid B (PAB) on proliferation, invasion and epithelial-to-mesenchymal transition (EMT) in pancreatic cancer cells and to explore the possible mechanism. Materials and Methods: The pancreatic cancer cell line SW1990 was cultured and treated with PAB dose- and time-dependent manners. Cell proliferation and invasion ability were measured by MTT assay and Matrigel/Transwell test, respectively. Semi-quantitative real-time polymerase chain reaction and Western blotting were conducted to detect the expression of EMT markers and the key molecules. Finally, nude mice subcutaneous transplantation tumor model was used to confirm the therapy efficacy of PAB. Results: PAB could inhibit SW1990 cell proliferation and invasion in time- and dose-dependent manners. Vimentin, fibronectin, N-cadherin, Snail, Slug, YAP, TEAD1, and Survivin were down-regulated (p<0.01), while E-cadherin, caspase-9, MST1, and pYAP were up-regulated (p<0.05). Combined PAB and gemcitabine treatment markedly restricted the tumor growth compared with gencitabin or PAB alone groups. Conclusion: PAB could inhibit the proliferation and invasion ability of pancreatic cancer cells through activating Hippo-YAP pathway and inhibiting the process of EMT.
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