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Matthew Pugliese,Jean-Michel Brismée,Brad Allen,Sean Riley,Justin Tammany,Paul Mintken 한국보건의료인국가시험원 2023 보건의료교육평가 Vol.20 No.-
Purpose This study investigated the prevalence of burnout in physical therapists in the United States and the relationships between burnout and education, mentorship, and self-efficacy. Methods This was a cross-sectional survey study. An electronic survey was distributed to practicing physical therapists across the United States over a 6-week period from December 2020 to January 2021. The survey was completed by 2,813 physical therapists from all states. The majority were female (68.72%), White or Caucasian (80.13%), and employed full-time (77.14%). Respondents completed questions on demographics, education, mentorship, self-efficacy, and burnout. The Burnout Clinical Subtypes Questionnaire (BCSQ-12) and self-reports were used to quantify burnout, and the General Self-Efficacy Scale (GSES) was used to measure self-efficacy. Descriptive and inferential analyses were performed. Results Respondents from home health (median BCSQ-12=42.00) and skilled nursing facility settings (median BCSQ-12=43.00) displayed the highest burnout scores. Burnout was significantly lower among those who provided formal mentorship (median BCSQ-12=39.00, P=0.0001) compared to no mentorship (median BCSQ-12=41.00). Respondents who received formal mentorship (median BCSQ-12=38.00, P=0.0028) displayed significantly lower burnout than those who received no mentorship (median BCSQ-12=41.00). A moderate negative correlation (rho=-0.49) was observed between the GSES and burnout scores. A strong positive correlation was found between self-reported burnout status and burnout scores (rrb=0.61). Conclusion Burnout is prevalent in the physical therapy profession, as almost half of respondents (49.34%) reported burnout. Providing or receiving mentorship and higher self-efficacy were associated with lower burnout. Organizations should consider measuring burnout levels, investing in mentorship programs, and implementing strategies to improve self-efficacy.
Flexible distributed Bragg reflectors as optical outcouplers for OLEDs based on a polymeric anode
Prontera Carmela Tania,Pugliese Marco,Giannuzzi Roberto,Carallo Sonia,Esposito Marco,Gigli Giuseppe,Maiorano Vincenzo 한국정보디스플레이학회 2021 Journal of information display Vol.22 No.1
Top-emitting OLEDs (TOLEDs) represent a promising technology for the development of nextgeneration flexible and rollable displays, thanks to their improved light outcoupling and their compatibility with opaque substrates. Metal thin films are the most used electrodes for the manufacturing of TOLEDs, but they show poor resistance to mechanical deformation, which compromises the long-term durability of flexible devices. This paper reports the exploitation of a dielectric mirror (DBR) based on seven pairs of TiO2 and SiO2 combined with a polymeric electrode as an alternative to the bottom metal electrode in flexible TOLEDs. The DBR showed a maximum reflectivity of 99.9% at about 550 nm, and a stop-band width of about 200 nm. The reflectivity remained unchanged after bending and treatment with water and solvents. Green TOLED devices were fabricated on top of DBRs, and demonstrated good stability in terms of electro-optical and colorimetric characteristics, according to varying viewing angles. These results demonstrate that the combination of the flexible DBR with the polymeric anode is an interesting strategy for improving the durability of flexible TOLEDs for display applications, implemented on different kinds of free-standing ultra-thin substrates.
Numerical wave interaction with tetrapods breakwater
Fabio Dentale,Giovanna Donnarumma,Eugenio Pugliese Carratelli 대한조선학회 2014 International Journal of Naval Architecture and Oc Vol.6 No.4
The paper provides some results of a new procedure to analyze the hydrodynamic aspects of the interactionsbetween maritime emerged breakwaters and waves by integrating CAD and CFD. The structure is modeled inthe numerical domain by overlapping individual three-dimensional elements (Tetrapods), very much like the real worldor physical laboratory testing. Flow of the fluid within the interstices among concrete blocks is evaluated by integratingthe RANS equations. The aim is to investigate the reliability of this approach as a design tool. Therefore, for the results'validation, the numerical run-up and reflection effects on virtual breakwater were compared with some empirical formulaeand some similar laboratory tests. Here are presented the results of a first simple validation procedure. Thevalidation shows that, at present, this innovative approach can be used in the breakwater design phase for comparisonbetween several design solutions with a significant minor cost.
( Alessandra Elvevi ),( Ivana Bravi ),( Aurelio Mauro ),( Delia Pugliese ),( Andrea Tenca ),( Ivan Cortinovis ),( Silvano Milani ),( Dario Conte ),( Roberto Penagini ) 대한소화기기능성질환·운동학회 2014 Journal of Neurogastroenterology and Motility (JNM Vol.20 No.1
Background/Aims Swallowing of cold liquids decreases amplitude and velocity of peristalsis in healthy subjects, using standard manometry. Patients with achalasia and non obstructive dysphagia may have degeneration of sensory neural pathways, affecting motor response to cooling. To elucidate this point, we used high-resolution manometry. Methods Fifteen healthy subjects, 15 non-obstructive dysphagia and 15 achalasia patients, after pneumatic dilation, were studied. The 3 groups underwent eight 5 mL single swallows, two 20 mL multiple rapid swallows and 50 mL intraesophageal water infusion (1 mL/sec), using both water at room temperature and cold water, in a randomized order. Results In healthy subjects, cold water reduced distal contractile integral in comparison with water at room temperature during single swallows, multiple rapid swallows and intraesophageal infusion (ratio cold/room temperature being 0.67 [95% CI, 0.48-0.85], 0.56 [95% CI, 0.19-0.92] and 0.24 [95% CI, 0.12-0.37], respectively). A similar effect was seen in non-obstructive dysphagia patients (0.68 [95% CI, 0.51-0.84], 0.69 [95% CI, 0.40-0.97] and 0.48 [95% CI, 0.20-0.76], respectively), whereas no changes occurred in achalasia patients (1.06 [95% CI, 0.83-1.29], 1.05 [95% CI, 0.77-1.33] and 1.41 [95% CI, 0.84-2.00], respectively). Conclusions Our data suggest impairment of esophageal reflexes induced by cold water in patients with achalasia, but not in those with non obstructive dysphagia. (J Neurogastroenterol Motil 2014;20:79-86)
Numerical wave interaction with tetrapods breakwater
Dentale, Fabio,Donnarumma, Giovanna,Carratelli, Eugenio Pugliese The Society of Naval Architects of Korea 2014 International Journal of Naval Architecture and Oc Vol.6 No.4
The paper provides some results of a new procedure to analyze the hydrodynamic aspects of the interactions between maritime emerged breakwaters and waves by integrating CAD and CFD. The structure is modeled in the numerical domain by overlapping individual three-dimensional elements (Tetrapods), very much like the real world or physical laboratory testing. Flow of the fluid within the interstices among concrete blocks is evaluated by integrating the RANS equations. The aim is to investigate the reliability of this approach as a design tool. Therefore, for the results' validation, the numerical run-up and reflection effects on virtual breakwater were compared with some empirical formulae and some similar laboratory tests. Here are presented the results of a first simple validation procedure. The validation shows that, at present, this innovative approach can be used in the breakwater design phase for comparison between several design solutions with a significant minor cost.
[6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A<sub>4</sub> Hydrolase
Jeong, Chul-Ho,Bode, Ann M.,Pugliese, Angelo,Cho, Yong-Yeon,Kim, Hong-Gyum,Shim, Jung-Hyun,Jeon, Young-Jin,Li, Honglin,Jiang, Hualiang,Dong, Zigang American Association for Cancer Research 2009 Cancer Research Vol.69 No.13
<P>[6]-Gingerol, a natural component of ginger, exhibits anti-inflammatory and antitumorigenic activities. Despite its potential efficacy in cancer, the mechanism by which [6]-gingerol exerts its chemopreventive effects remains elusive. The leukotriene A(4) hydrolase (LTA(4)H) protein is regarded as a relevant target for cancer therapy. Our in silico prediction using a reverse-docking approach revealed that LTA(4)H might be a potential target of [6]-gingerol. We supported our prediction by showing that [6]-gingerol suppresses anchorage-independent cancer cell growth by inhibiting LTA(4)H activity in HCT116 colorectal cancer cells. We showed that [6]-gingerol effectively suppressed tumor growth in vivo in nude mice, an effect that was mediated by inhibition of LTA(4)H activity. Collectively, these findings indicate a crucial role of LTA(4)H in cancer and also support the anticancer efficacy of [6]-gingerol targeting of LTA(4)H for the prevention of colorectal cancer.</P>