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      • KCI등재

        A Review on Flow Characteristics of the Straight and Coiled Capillary Tubes

        Jadhav Pravin,Agrawal Neeraj 대한설비공학회 2021 International Journal Of Air-Conditioning and Refr Vol.29 No.3

        A detailed literature review on the flow characterization of the capillary tubes is presented in this paper. The flow behavior is reviewed for straight, helically, and spirally coiled capillary tubes at different operating and geometric conditions by considering various aspects in the tube. This paper summarizes experimental and numerical study on the adiabatic and nonadiabatic straight and coiled capillary tubes at different geometries conditions. The vital information of the range of the tube geometry and operating conditions are discussed, which can be utilized for further studies on the capillary tube. Various methodologies with generalized correlations are indicated. It has been observed that there are even more studies need to do with environmentally friendly refrigerants with various practical aspects in the capillary tube. It would be interesting to find the coiling effect on the design and simulation of the capillary tube. In addition to that more experimental and numerical studies need to explore the nonadiabatic coiled capillary tube. It would be fascinating to study the metastable condition in the capillary tube and set suitable relations to present its effect on the mass flow rate.

      • KCI등재

        Numerical Study on Choked Flow of CO2 Refrigerant in Helical Capillary Tube

        Pravin Jadhav,Neeraj Agrawal 대한설비공학회 2018 International Journal Of Air-Conditioning and Refr Vol.26 No.3

        This paper presents a numerical study on an adiabatic helical capillary tube employing homogenous and choked flow conditions of a CO2 transcritical system. The theoretical model is based on the fundamental principle of fluid dynamics and thermodynamics. The result of the present model validates with the previously published data. The influence of operating and geometric parameters on the performance of the capillary tube has been evaluated. Flow characterizations of choked and unchoked flow conditions are determined. As the evaporator pressure drops, from unchoked condition to choked state, the percentage change in mass flow rate is minimal. A simulation graph is developed which has been helpful for the design of the helical capillary tube. The choked flow condition in a capillary tube is avoided by either increasing tube diameter of the fixed length tube or decreasing the length of the fixed tube diameter.

      • KCI등재

        Choked Flow Behavior of CO2 Refrigerant Flowing Through the Spiral Capillary Tube

        Pravin Jadhav,Neeraj Agrawal 대한설비공학회 2020 International Journal Of Air-Conditioning and Refr Vol.28 No.3

        The flow characteristics of CO2 refrigerant are numerically studied for an adiabatic spirally coiled capillary tube employing choked flow conditions. The mass, momentum and energy conservation equations are used to develop a numerical model. The existing model is verified with the published results. The choked flow behavior at various geometric parameters viz. tube diameter and spiral pitch is studied. Similarly, the influence of these parameters on the mass flow rate through the tube is observed. A significant change in mass flow rate is due to a change in tube diameter, whereas a minimal variation is observed with the change in surface roughness and spiral pitch. Moreover, it is observed that the coiling effect has a significant influence on the flow behavior of the spiral capillary tube. As the pressure decreases, from unchoked to the choked pressure in the evaporator by 63.46%, the mass flow rate increases by 9.46% only. The capillary tube choking is circumvented by increasing spiral pitch, tube diameter and decreasing the length of the tube. A unique nomogram is developed that gives the best understanding of choked and unchoked flow conditions, that graphical representation is useful to design the spirally coiled capillary tube. By using that, the choked length is identified for the known mass flow rate, even more, the choked mass flow rate is known for a given tube length. Moreover, for the given tube length and evaporator temperature, a nomogram is useful to the known choked values of mass flow rate and exit values of the evaporator pressure and quality of refrigerant.

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        Synthesis and Biological Activity of (2-Substituted-4-methylthiazol-5-yl) (4-substituted piperazin-1-yl)methanone Derivatives

        Mhaske, Pravin C.,Shelke, Shivaji H.,Raundal, Hemant N.,Jadhav, Rahul P. Korean Chemical Society 2014 대한화학회지 Vol.58 No.1

        In the present study a novel series of (2-substituted-4-methylthiazol-5-yl)(4-substituted piperazin-1-yl)methanone derivatives were synthesized by reaction of 2-substituted-4-methylthiazole-5-carboxylic acid with N-substituted benzyl piperazine by using 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide hydrochloride (EDCl) and 1-hydroxybenzotriazole (HOBt) in DMF. All the newly synthesized compounds were characterized by spectral methods. The title compounds were screened for in vitro antibacterial activity. Most of the compounds show moderate to good antimicrobial activity.

      • Development and evaluation of orodispersible tablets using a natural polysaccharide isolated from Cassia tora seeds

        Harshal Pawar,Chhaya Varkhade,Pravin Jadhav,Kavita Mehra 한국한의학연구원 2014 Integrative Medicine Research Vol.3 No.2

        Background: Orodispersible tablets or fast dissolving tablets dissolve or disintegrate imme-diately on the patients’ tongue or buccal mucosa. This drug delivery system is suitable fordrugs undergoing high first pass metabolism. It improves bioavailability, reduces dosingfrequency, and thereby minimizes the side effects and also makes the dosage form morecost-effective. In this study, polysaccharide isolated from the seeds of Cassia tora was inves-tigated as a superdisintegrant in the orodispersible tablets. The model drug chosen wasvalsartan, an antihypertensive drug.Methods: Valsartan tablets were prepared separately using different concentrations (1%, 2.5%,5%, and 7.5% w/w) of isolated C. tora seed polysaccharide (natural) and sodium starch glyco-late (synthetic) as superdisintegrant by the direct compression method. Evaluation of tabletswas done for various pre- and postcompression parameters. The stability studies were per-formed on optimized formulation F4. The disintegration time and in vitro drug release of theformulation F4 were compared with marketed formulations (conventional tablets).Results: The drug excipient interactions were characterized by Fourier transform infraredstudies. The formulation F4 containing 7.5% polysaccharide showed good wetting timeand disintegration time as compared to a formulation prepared using a synthetic super-disintegrant at the same concentration level. Hence, batch F4 was considered optimizedformulation.Conclusion: The present work revealed that C. tora seed polysaccharide has a good potentialas a disintegrant in the formulation of orodispersible tablets. Because C. tora polysaccharideis inexpensive as compared to synthetic superdisintegrants, nontoxic, compatible, and easyto manufacture, it can be used in place of currently marketed superdisintegrants.

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