http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Piyapan Prueksapanich (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Liver Fluke-Associated Biliary Tract Cancer
( Piyapan Prueksapanich ),( Panida Piyachaturawat ),( Prapimphan Aumpansub ),( Wiriyaporn Ridtitid ),( Roongruedee Chaiteerakij ),( Rungsun Rerknimitr ) 대한간학회 2018 Gut and Liver Vol.12 No.3
Cholangiocarcinoma (CCA) is an aggressive cancer arising from epithelial cells of the bile duct. Most patients with CCA have an unresectable tumor at the time of diagnosis. In Western countries, the risk of CCA increases in patients with primary sclerosing cholangitis, whereas liver fluke infection appears to be the major risk factor for CCA in Asian countries. A diagnosis of liver fluke infection often relies on stool samples, including microscopic examination, polymerase chain reaction-based assays, and fluke antigen detection. Tests of serum, saliva and urine samples are also potentially diagnostic. The presence of liver fluke along with exogenous carcinogens magnifies the risk of CCA in people living in endemic areas. The “liver fluke-cholangiocarcinoma” carcinogenesis pathways consist of mechanical damage to the bile duct epithelium, immunopathologic and cellular reactions to the liver fluke’s antigens and excretory/secretory products, liver fluke-induced changes in the biliary tract microbiome and the effects of repeated treatment for liver fluke. A vaccine and novel biomarkers are needed for the primary and secondary prevention of CCA in endemic areas. Importantly, climate change exerts an effect on vector-borne parasitic diseases, and awareness of liver fluke should be enhanced in potentially migrated habitat areas. (Gut Liver 2018;12:236- 245)
-
Piyapan Prueksapanich,Thanawat Luangsukrerk,Rapat Pittayanon,Anapat Sanpavat,Rungsun Rerknimitr 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.2
Background/Aims: This study aimed to evaluate the diagnostic accuracy of dual-focus narrow-band imaging (dNBI) andLugol’schromoendoscopy (LCE) combined with probe-based confocal laser endomicroscopy (pCLE) to screen for esophageal squamouscell neoplasms (ESCNs) in patients with a history of head and neck cancer. Methods: From March to August 2016, dNBI was performed. Next, LCE was performed, followed by pCLE and biopsy. Histology hashistorically been the gold standard to diagnose ESCN. The sensitivity, specificity, positive predictive value (PPV), negative predictivevalue (NPV), and accuracy of dNBI and LCE adjunct with pCLE were determined. Results: Twenty-four patients were included. Ten ESCNs were found in 8 patients (33%). Forty percent of high-graded intraepithelialneoplasias and all low-grade intraepithelial neoplasias were overlooked by dNBI. The sensitivity, specificity, PPV, NPV, and accuracy ofdNBI vs. LCE combined with pCLE were 50% vs. 80%, 62% vs. 67%, 36% vs. 44%, 75% vs. 91%, and 83% vs. 70%, respectively. Conclusions: The use of dNBI to detect ESCN was suboptimal. LCE with pCLE following dNBI had additional value for detectingesophageal dysplasia not detected by dNBI. The use of pCLE to detect dNBI-missed lesions yielded a high NPV, while pCLE-guidedbiopsy could reduce the number of unnecessary biopsies.
-
( Satimai Aniwan ),( Julajak Limsrivilai ),( Supot Pongprasobchai ),( Nonthalee Pausawasdi ),( Piyapan Prueksapanich ),( Natanong Kongtub ),( Rungsun Rerknimitr ) 대한장연구학회 2021 Intestinal Research Vol.19 No.2
Background/Aims: The incidence of ulcerative colitis (UC) in Thailand (crude incidence rate of 0.28 per 100,000 persons) is much lower than in the West. The burden of UC varies in different populations. The aim of this study was to evaluate the natu ral history of UC over the two decades in Bangkok, Thailand. Methods: This retrospective study included patients who were diagnosed with UC between 2000 and 2018 in 2 university hospitals. To evaluate changes in the disease course, we stratified patients into 2000-2009 cohort and 2010-2018 cohort. The cumulative probability of endoscopic healing, UC-related hospi talization and colectomy was estimated using the Kaplan-Meier method. Results: A total of 291 UC patients were followed for total of 2,228 person-years. Comparison between 2 cohorts, there were no differences in disease pattern and severity whereas an increase in the combination use of oral and topical mesalamine and the early use of thiopurine was observed. Only 1% of patients for each cohort required biologic agent at 5 years. The rate of achieving mucosal healing increased from 15% to 46% at 3 years (P<0.01). The rate of UC-related hospitalization decreased from 30% to 21% at 5 years (P<0.05). The rate of colectomy decreased from 6% to 2% at 5 years (P<0.05). Conclusions: The natural history of UC in a low incidence country was less ag gressive than the West. Over the past two decades, the rates of UC-related hospitalization and colectomy have been decreasing which were similar to the West. (Intest Res 2021;19:186-193)
KCI
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
