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RISS 인기검색어
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- 저자 : Peng Chin Kek (검색결과 2 건)
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Wann Jia Loh,Dawn Shao Ting Lim,Lih Ming Loh,Peng Chin Kek 대한내분비학회 2018 Endocrinology and metabolism Vol.33 No.3
Background: The aim of this study was to investigate the factors associated with resolution of hypertension after adrenalectomy inpatients with primary aldosteronism. A secondary aim was to describe our use of the contralateral ratio in adrenal venous sampling(AVS) in the setting of suboptimal successful cannulation rates. Methods: A retrospective review of patients who underwent AVS followed by unilateral adrenalectomy for primary aldosteronismwas performed. Results: Complete resolution of hypertension and hypokalemia was seen in 17 of 40 patients (42.5%), while a clinical improvementin hypertension was seen in 38 of 40 (95%). Shorter duration of hypertension, mean aldosteronoma resolution score (ARS), and ahigh ARS of 3 to 5 were associated with resolution of hypertension after adrenalectomy (P=0.02, P=0.02, and P=0.004, respectively). Of the individual components of ARS, only a duration of hypertension of ≤6 years was associated with resolution of hypertensionafter adrenalectomy (P=0.03). Conclusion: A shorter duration of hypertension was significantly associated with resolution of hypertension after adrenalectomy inpatients with primary aldosteronism.
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Bariatric Surgery in Kidney Transplant Candidates and Recipients: Experience at an Asian Center
Sarah Ying Tse Tan,Phong Ching Lee,Sonali Ganguly,Peng Chin Kek,Terence Kee,Quan Yao Ho,Sobhana Thangaraju 대한비만학회 2022 Journal of obesity & metabolic syndrome Vol.31 No.4
Background: Kidney transplant (KT) candidates and recipients with obesity experience more frequent complications such as infection, poorer allograft outcomes, diabetes, and mortality, limiting their eligibility for transplantation. Bariatric surgery (BS) is not commonly performed among KT patients given concerns about immunosuppression absorption, wound healing, infections, and graft outcomes. Its role has not been described before in an Asian KT patient setting. Methods: A retrospective review of patients who underwent BS at the largest KT center in Singapore from 2008 to 2020 was conducted. Metabolic outcomes, immunosuppression doses, graft outcomes, and mortality were studied. Results: Seven patients underwent BS and KT (4 underwent BS before KT, 3 underwent BS after KT; 4 underwent sleeve gastrectomy, 3 underwent gastric bypass). Mean total weight losses of 23.8% at 1 year and 18.6% at 5 years post-BS were achieved. Among the five patients with diabetes, glycemic control improved after BS. There were no deaths in the first 90 days or graft loss in the first year after KT and BS. Patients who underwent BS after KT had no significant changes in immunosuppression dose. Conclusion: BS can be safely performed in KT recipients and candidates and results in sustainable weight losses and improvements in metabolic comorbidities. Although no major complications were observed in our study, close monitoring of this complex group of patients is imperative.
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