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- 저자 : Lih Ming Loh (검색결과 1 건)
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Wann Jia Loh,Dawn Shao Ting Lim,Lih Ming Loh,Peng Chin Kek 대한내분비학회 2018 Endocrinology and metabolism Vol.33 No.3
Background: The aim of this study was to investigate the factors associated with resolution of hypertension after adrenalectomy inpatients with primary aldosteronism. A secondary aim was to describe our use of the contralateral ratio in adrenal venous sampling(AVS) in the setting of suboptimal successful cannulation rates. Methods: A retrospective review of patients who underwent AVS followed by unilateral adrenalectomy for primary aldosteronismwas performed. Results: Complete resolution of hypertension and hypokalemia was seen in 17 of 40 patients (42.5%), while a clinical improvementin hypertension was seen in 38 of 40 (95%). Shorter duration of hypertension, mean aldosteronoma resolution score (ARS), and ahigh ARS of 3 to 5 were associated with resolution of hypertension after adrenalectomy (P=0.02, P=0.02, and P=0.004, respectively). Of the individual components of ARS, only a duration of hypertension of ≤6 years was associated with resolution of hypertensionafter adrenalectomy (P=0.03). Conclusion: A shorter duration of hypertension was significantly associated with resolution of hypertension after adrenalectomy inpatients with primary aldosteronism.
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