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Park Kyeong-Yeol,Lee Kyu-Jae,Kim In-Sik,Yang Eun-Ju,Lim Su-jung,Lim Byung-Hyuk,Ryang Yong-Suk The Korean Society for Biomedical Laboratory Scien 2005 Journal of biomedical laboratory sciences Vol.11 No.3
Mast cells and goblet cells have been known to protect the host against parasites. In this study, we examined the response of the mast cells and goblet cells over a period of 6 weeks in the duodenum, jejunum and ileum of C3H/HeN and C57BL/6 mice infected with Echinostoma hortense (E. hortense). In addition, we investigated whether the worm recovery rate of uninfected mice (the control group) or E. hortense-infected mice (the experimental group) was associated with the number of mast cells and goblet cells. The worm recovery rate was higher in the C3H/HeN mice than in the C57BL/6 mice. The number of goblet cells significantly increased in the experimental group of the C3H/HeN and C57BL/6 mice compared with the control group of both strains (P<0.005). Worm recovery peaked 3 weeks after the infection of the C57BL/6 mice and at 2 weeks after the infection of the C3H/HeN mice, and it was higher in the duodenum than in the jejunum and ileum. However, the infected site in the intestine had no relation with worm expulsion. In the C3H/HeN and C57BL/6 mice, the number of goblet cells in the experimental group was significantly higher than that in the control group (P<0.005). The number reached a peak 2 weeks after the infection and it even increased in duodenum, jejunum and ileum. The increased number of goblet cells was retained 6 weeks after infection. The number of goblet cells was higher in the C3H/HeN mice than in the C57BL/6 mice (P<0.01). These results indicate that goblet cells are related with the worm expulsion. Furthermore, immunohistostaining of the antral intestinal walls for lectin showed the significant increase of the number of goblet cells in the experimental group (P<0.001). The high infection rate in the duodenum was found during the early infection. An increased infection rate in the jejunum and ileum was found 3 weeks after infection and the infection rate was higher in the C3H/HeN mice than in the C57BL/6 mice. Taken together, the present study indicates that goblet cells, rather than mast cells, may play critical roles in parasite expulsion.
여성의 전쟁체험 구술에 나타난 가족관계의 갈등과 대응방식
박경열 ( Park Kyeong-yeol ) 한국문학치료학회 2016 문학치료연구 Vol.40 No.-
이 연구는 여성의 전쟁체험 구술에 나타난 가족관계의 갈등과 대응방식을 살펴보았다. 전쟁체험 구술에 나타난 가족관계의 갈등은 부녀관계와 부부관계에서 발생한 것이다. 실제 부녀관계와 부부관계에 나타난 갈등의 원인과 화자가 구술하는 갈등의 원인이 다르게 나타났다. 화자가 갈등을 원인을 다르게 보는 이 관점은 화자의 의도가 반영된 것이다. 부녀관계나 부부관계에서 공통적으로 나타난 현상은 화자의 관점이 보고 싶은 것 혹은 믿고 싶은 것을 원인으로 판단한다는 것이다. 딸이나 혹은 아내가 믿고 싶은 것만 믿으려 했던 이유는 고난을 자처하기 위해서이다. 남편을 장애로 여기고 아버지를 고난으로 여기는 것은 결국 고난을 짊어지고 그 고난을 감수하려했던 의도 때문이었다. 화자 스스로 책임을 자처하거나 책임을 짊어지는 행위는 스스로를 단죄하며 고난을 감내하는 자신을 보여주기 위함이다. 화자는 아버지를 디딤돌로 삼고 걸림돌인 남편을 제거함으로써 자신의 삶을 완성한다. 이런 점에서 배척의 화법으로 구술하는 가족관계의 갈등은 자신의 존재가치를 입증하고 드러내는 한 방법인 것이다. 화자는 고통을 감내하며 자신 스스로를 구제하고 그럼으로써 자기를 극복하여 자신을 일구어 낸 성공한 자기만의 서사를 완성한 것이다. This research is aims at looking into family conflicts and reactions to family members sharing their experiences of war, specifically in father-daughter relationships and spousal relationships. The relationship between fathers and daughters is rooted in positioning conditions. Conflict in the spousal relationship comes from the husband`s experience as seen from the wife`s point of view. Whether a father-daughter or a spousal relationship, what we can clearly see is that the speaker believes they are the source of conflicts, regardless of what causes the conflict actually. These two cases of conflict also share the characteristic that the speaker`s point of view is determined by what they want to see or believe. The reason daughters and wives only believe what they want to believe is that they want to bear the hardship by themselves. They convince themselves to bear the hardship while seeing their husband as a wall and their father as a hardship. In this way, they reveal that bearing their hardship is motivated by feelings of guilt. The speakers are willing to overcome the hardship and live successful lives while creating a step against their fathers and rejecting their husbands, who present a hurdle to their success. In this point of view, the conflict from hearing about their husbands and fathers` war experiences reflects the hardships they face to save themselves and be successful against the odds.
한 대기업 근로자들의 직무스트레스와 정신건강과의 관련성
유경열 ( Kyeong Yeol Yu ),이경종 ( Kyung Jong Lee ),민경복 ( Kyoung Bok Min ),박규철 ( Kyu Chul Park ),채상국 ( Sang Kug Chai ),박재범 ( Jae Bum Park ) 한국산업위생학회 2011 한국산업보건학회지 Vol.21 No.3
Objectives: This study was conducted to investigate the association between job stress and mental health among male and female workers in a large electric manufacture company. Methods: A cross-sectional study was carried out on 3,228 employees who participated in annual medical check-up working in a large electric manufacture company in Gyeonggi Province. Medical check-up and self-administrated questionnaire were performed at the same time. Korean Occupational Stress Scale Short Form (KOSS-SF) and Psychosocial Wellbeing Index Short Form (PWI-SF) were applied to assess occupational stress and mental health. Hierarchical multiple linear regression and multiple logistic regression were performed to estimate the association between job stress and mental health. Results: The proportion of high risk of mental health was 17.1% in male, and 46.9% in women. Job stress had a greater effect on mental health than other general and work characteristics. All subscales of job stress were revealed to affect mental health. Bad occupational climate and lack of reward are the strongest risk factors in mental health of male and female respectively. Conclusions: Our results suggest that job stress could affect mental health among large electronic manufacture workers.
국내 민간병원에서 치료한 다제내성결핵 환자의 치료 결과 및 예후 인자
박진경 ( Jin Kyeong Park ),고원중 ( Won-Jung Koh ),김덕겸 ( Deog Kyeom Kim ),김은경 ( Eun Kyung Kim ),김유일 ( Yu Il Kim ),김희진 ( Hee Jin Kim ),김태형 ( Tae-Hyung Kim ),김재열 ( Jae Yeol Kim ),박무석 ( Moo Suk Park ),박이내 ( I- 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.69 No.2
Background: The increasing rate of drug-resistant tuberculosis (TB) is a threat to the public health and TB control. In Korea, about 75~80% of TB patients are treated in private hospitals and the rate has been continuously increasing since 2000. Methods: On a retrospective basis, we enrolled 170 newly diagnosed with or retreated for multidrug-resistant TB (MDR-TB) in 2004 from 21 private hospitals. We extracted the following demographics and treatment history from patient medical records: initial treatment outcomes, cumulative survival rates, treatment outcomes, and prognostic factors. Results: Of the 170 patients, the majority were male (64.1%), the mean age was 44.5 years old, and mean body-mass-index was 20.2kg/m2. None of the patients tested positive for HIV. Eleven (6.5%) were confirmed to have extensively drug-resistant TB (XDR-TB) at treatment initiation. Treatment success rates were not different between XDR-TB (36.4%, 4/11) and non-XDR MDR-TB (51.6%, 82/159). Default rate was high, 21.8% (37/170). Far advanced disease on X-ray was a significant negative predictor of treatment success; advanced disease and low BMI were risk factors for all-cause mortality. Conclusion: In private hospitals in Korea, the proportion of XDR-TB in MDR-TB was comparable to previous data. The treatment success rate of MDR-/XDR-TB remains poor and the failure rate was quite high. Adequate TB control policies should be strengthened to prevent the further development and spread of MDR-/XDR-TB in Korea.