http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
( Seon Hee Oh ),( Suk Whee Kim ),( Dong Joon Kim ),( Sang Hun Kim ),( Kyung Joon Lim ),( Kichang Lee ),( Ki Tae Jung ) 대한통증학회 2021 The Korean Journal of Pain Vol.34 No.4
Background: This study investigated the effect of intrathecal Sec-O-glucosylhamaudol (SOG) on the p38/c-Jun N-terminal kinase (JNK) signaling pathways, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)-related inflammatory responses, and autophagy in a spinal nerve ligation (SNL)-induced neuropathic pain model. Methods: The continuous administration of intrathecal SOG via an osmotic pump was performed on male Sprague-Dawley rats (n = 50) with SNL-induced neuropathic pain. Rats were randomized into four groups after the 7th day following SNL and treated for 2 weeks as follows (each n = 10): Group S, sham-operated; Group D, 70% dimethylsulfoxide; Group SOG96, SOG at 96 μg/day; and Group SOG192, SOG at 192 μg/day. The paw withdrawal threshold (PWT) test was performed to assess neuropathic pain. Western blotting of the spinal cord (L5) was performed to measure changes in the expression of signaling pathway components, cytokines, and autophagy. Additional studies with naloxone challenge (n = 10) and cells were carried out to evaluate the potential mechanisms underlying the effects of SOG. Results: Continuous intrathecal SOG administration increased the PWT with p38/ JNK mitogen-activated protein kinase (MAPK) pathway and NF-κB signaling pathway inhibition, which induced a reduction in proinflammatory cytokines with the concomitant downregulation of autophagy. Conclusions: SOG alleviates mechanical allodynia, and its mechanism is thought to be related to the regulation of p38/JNK MAPK and NF-κB signaling pathways, associated with autophagy during neuroinflammatory processes after SNL.
초음파 중재 하 황색인대 침도시술 방법에 대한 프로토콜
Kang Kyungho,Oh Kichang,Kim Jaehyo,Chu Hongmin 대한침도의학회 2023 대한침도의학회지 Vol.7 No.1
Background: The aim of this article is to propose the safe and effective protocol for ultrasound-guided acupotomy procedure at ligamentum flavum. Deep needling at the ligament flavum can cause side effects such as leakage of cerebrospinal fluid or hematoma, or exacerbation of the patient’s symptoms, which are difficult to respond to in primary medical institutions. In this regard, the need to present a safer and more accurate method of needling at ligamentum flavum is enhanced. Methods: While treating 12 patients aged 60-80 years, the method of needling the shortest length with identifing the tip of acupuncture on the image was studied. An ultrasound machine was used with GE LOGIQ P9 XDclear and C1-6D Single Crystal Convex Probe. The initial study used a SMC 0.40×60 mm needle. After the operation became proficient with the needle, MAANSHAN BOND MEDICAL INSTRUMENTS CO. LTD. GB 60×60 acupotomy was used. Results: A safe procedure method and a manual for education methods were proposed. Conclusion: Because of the long axis entry, the procedure can be performed without missing the full length and tip of the acupuncture on image. It can be performed with small invasion compared to previous in-plane studies performed by laying down the angle.
Sun Teh Cheng,Oh Kichang,Kim Gyeongchan 대한침도의학회 2023 대한침도의학회지 Vol.7 No.1
Background: The aim of this report is to report the effect of Acupotomy on Oculomotor Nerve Palsy. Methods: A 78-year-old male patient was diagnosed with Oculomotor Nerve Palsy and complained of Diplopia, right eye movement disorder. This patient received acupuncture treatment on the anterior border of posterior tubercle of cervical transverse process, upper border of right zygomatic arch, right Jingming acupoint (BL1). Results: As a result of 20 acupotomy treatments from November 14 to February 20, adduction in the right eye completely improved, and the diplopia which occurred when looking to the left also disappeared. Conclusion: This study suggests that acupotomy treatment may be effective in eye movement disorder caused by oculomoter nerve palsy and diplopia.
Yang, Tae-Ho,Oh, Sun-Young,Kwak, Kichang,Lee, Jong-Min Informa Healthcare USA, Inc. 2014 Neuro-ophthalmology Vol.38 No.4
<P>The authors describe a 35-year-old man suffering from homonymous hemianopia after head trauma 4 years before but with negative magnetic resonance imaging (MRI) findings. Brain fluorine-18 fluorodeoxyglucose positron emission tomography (<SUP>18</SUP>FDG-PET) showed hypometabolism at the unilateral occipital lobe and crossed cerebellar hemisphere, and diffusion tensor imaging (DTI) revealed that the ipsilateral optic radiations were completely interrupted. The crossed cerebellar diaschisis (CCD) observed in the chronic stage of brain damage was caused by cerebellar suppression of the cerebral blood flow due to an involvement of the corticopontocerebellar tract. PET and DTI provide objective means for determining the relationship of functional deficits to head trauma, even in cases where the injury was sustained years prior to the evaluation.</P>