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소프트웨어 개발 프로젝트의 위험요인 도출에 대한 델파이 연구
정경수,강명희,김용 한국정보시스템학회 2004 情報시스템硏究 Vol.13 No.1
Most of the software development projects bear risks that need analysis and management. Risk management plays a critical role for the success of software project management. In this study, we have used delphi method to delineate critical risk factors. The study pulls out 20 project risk factors from 21 project managers. It is certainly clear that certain features are more risky than others. Our study shows that unrealistic cost estimation and changes in scope and objective are more risky than other features.
Kim, Myeong-Seong,Lee, Geon-Woo,Lee, Suk-Woo,Jeong, Jun Hui,Mhamane, Dattakumar,Roh, Kwang Chul,Kim, Kwang-Bum Elsevier 2017 Journal of industrial and engineering chemistry Vol.52 No.-
<P><B>Abstract</B></P> <P>LiFePO<SUB>4</SUB>/graphene microspheres are synthesized while avoiding the restacking of graphene sheets using a spray-drying process and a subsequent heat treatment. To determine an optimal condition for preventing the restacking of graphene sheets in the composites, we control the weight ratio of LiFePO<SUB>4</SUB> to rGO. When the amount of rGO in the composite exceeds a specific amount, the rGO sheets are spontaneously restacked. The restacked rGO sheets impede the Li ion movement, which is leading to the deterioration of the electrochemical performance at high C-rates. The microspheres synthesized exhibit a high specific capacity, excellent rate capability, and good cycling stability.</P> <P><B>Highlights</B></P> <P> <UL> <LI> LFP/graphene composite was synthesized while avoiding graphene sheets restacking. </LI> <LI> Degree of graphene sheets restacking affected the rate capability of the composites. </LI> <LI> Restacked graphene sheets blocked Li ion movement in the electrode. </LI> <LI> LFP/graphene composite exhibited improved rate capability and cyclability. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>To fully exploit the properties of graphene as an electrode material for energy storage devices, it is important to prevent the restacking of graphene sheets. In this study, three-dimensional (3D) micro-spherical LiFePO<SUB>4</SUB>/graphene composites were synthesized while avoiding the restacking of graphene sheets using a scalable, facile, and simple spray-drying process and a subsequent heat treatment. In this system, the LiFePO<SUB>4</SUB> nanoparticles acted not only as the active material but also as the spacer between the graphene sheets. To determine an optimal condition for preventing the restacking of graphene sheets in the composites, we controlled the weight ratio of LiFePO<SUB>4</SUB> to graphene. During this process, the degree of restacking of graphene sheets in the composites had a significant effect on their morphology and electrochemical properties. The 3D LiFePO<SUB>4</SUB>/graphene microspheres were micrometer-sized spherical assemblies with 100nm-sized LiFePO<SUB>4</SUB> nanoparticles and graphene sheets. The microspheres exhibited a high specific capacity of 163mAhg<SUP>−1</SUP> at 0.1 C-rate, excellent rate capability (65% of the initial discharge capacity (0.1 C-rate) at 30 C-rate), and good cycling stability (81.6% capacity retention after 1000 cycles).</P> <P>[DISPLAY OMISSION]</P>
Kim, Jong-shu,Kim, Yong-hwan,Choi, Min-cheol,Kim, Gon-sup,Kim, Chung-hui,Park, Jeong-hee,Hah, Dae-sik,Heo, Jung-ho,Jeong, Myeong-ho,An, Dong-won The Korean Society of Veterinary Science 1999 大韓獸醫學會誌 Vol.39 No.4
A national animal health monitoring system(NAHMS) in Gyeongnam area was started from 1997 to develop statistically valid data for use in estimating disease frequencies in dairy cattle, and the associated costs. The objectives of this study were to : (1) discribe what was done to implement and maintain the system in Gyeongnam ; (2) present selected disease frequencies ; (3) discuss the epidemiological consideration of what was done and implications for the results obtained. Veterinary Medical Officers(VMOs-professors and graduate students from Gyeongsang National University, Faculty of Gyeongnam Livestock Promotion Institute, and Clinic veterinarians) served as data collectors. After training on current disease and management problems of dairy cattle, interview techniques, sampling methods, and data collection instruments, the VMOs participated in selection of the sample herds and data gathering. Forty of 167 dairy herds were selected randomly and the VMOs visited farms once a month for 12 months to collect data about management, disease, inventory, production, preventive treatment, financial and any other relevant data. Strict data quality control devices were used. Specific feed-back was developed for the producers and data collectors. Of the three age groups studied, cows had the greatest number of disease problems. The six disorders found most frequently were (from the highest to the lowest) breeding problems, clinical mastitis, birth problems, gastrointestinal problems. metabolic problems, and lameness. In young stock, respiratory, multiple system, breeding problems, and gastrointestinal problems were pre dominant, whereas in calves, gastrointestinal, respiratory, and integumental problems were major.
Kim, In Hye,Lee, Tae-Kyeong,Cho, Jeong Hwi,Lee, Jae-Chul,Park, Joon Ha,Ahn, Ji Hyeon,Shin, Bich-Na,Chen, Bai Hui,Tae, Hyun-Jin,Kim, Yang Hee,Kim, Jong-Dai,Kim, Young-Myeong,Won, Moo-Ho,Kang, Il Jun D.A. Spandidos 2017 MOLECULAR MEDICINE REPORTS Vol.16 No.1
<P><I>Chrysanthemum indicum</I> Linné extract (CIL) is used in herbal medicine in East Asia. In the present study, gerbils were orally pre-treated with CIL, and changes of antioxidant enzymes including superoxide dismutase (SOD) 1 and SOD2, catalase (CAT) and glutathione peroxidase (GPX) in the hippocampal CA1 region following 5 min of transient cerebral ischemia were investigated and the neuroprotective effect of CIL in the ischemic CA1 region was examined. SOD1, SOD2, CAT and GPX immunoreactivities were observed in the pyramidal cells of the CA1 region and their immunoreactivities were gradually decreased following ischemia-reperfusion and barely detectable at 5 days post-ischemia. CIL pre-treatment significantly increased immunoreactivities of SOD1, CAT and GPX, but not SOD2, in the CA1 pyramidal cells of the sham-operated animals. In addition, SOD1, SOD2, CAT and GPX immunoreactivities in the CA1 pyramidal cells were significantly higher compared with the ischemia-operated animals. Furthermore, it was identified that pre-treatment with CIL protected the CA1 pyramidal cells in the CA1 region using neuronal nuclei immunohistochemistry and Fluoro-Jade B histofluorescence staining; the protected CA1 pyramidal cells were 67.5% compared with the sham-operated animals. In conclusion, oral CIL pre-treatment increased endogenous antioxidant enzymes in CA1 pyramidal cells in the gerbil hippocampus and protected the cells from transient cerebral ischemic insult. This finding suggested that CIL is promising for the prevention of ischemia-induced neuronal damage.</P>
지역사회 및 병원 임상검체에서 분리한 대장균의 항생제 내성 양상
Kim, Yong-Hui,Go, Jong-Myeong,Gong, Young-Woo,Oh, Bo-Young,Kim, Jung-Hee,Kim, Hye-Young,Lee, Mi-Yeon,Koh, Yeon-Ja,Hwang, Kyoung-Wha,JeGal, Seung,Lee, Jae-Mann 한국미생물학회 2006 미생물학회지 Vol.42 No.4
본 연구에서는 지역사회 일반인에게 분리된 대장균과 종합병원을 내원한 설사환자에서 분리한 대장균에 대하여 항생제 내성현황을 모니터링 하였다. 2006년 2월$\sim$7월까지 인천의 지역사회 일반인 692명의 대변으로부터 순수하게 분리된 대장균 491 균주에 대해 항생제 내성균을 조사한 결과, tetracycline 내성이 46.6%, ampicillin 내성이 41.1% ticarcillin 내성이 37.9%였다. 또한 3차 의료기관의 설사환자에서 분리된 대장균 120 균주에 대하여 ampicillin 내성이 66.9%, ticareillin 내성이 63.8%, tetracycline 내성이 47.2%였다. $\beta$-lactam 분해효소(extended spectrum $\beta$-lactamase)를 생성하는 대장균은 지역사회 일반인의 경우 0.6%, 설사질환자의 경우4..1%로 각각 분리되었다. We monitored antibiotic resistance of Escherichia coli isolates from healthy volunteers of community and hospital patients from February to July in 2006. From disc diffusion test on 4915 E. coli isolates from healthy volunteers of the community, the resistance rates were as follows; tetracycline resistant, 46.6%; ampicillin resistant, 41.1%; ticarcillin resistant,37.9%. From disc diffusion test on 120 E. coli isolates from hospital patients, the resistance rates were as follows: ampicillin resistant, 66.9%; ticarcillin resistant, 63.8%; tetracycline resistant, 47.2%. Extended spectrum $\beta$-lactamase producing E. coli were isolated 0.6% and 4.1% from healthy volunteers and hospital patients.
Kim, Hyun-Soo,Jung, Se-Hui,Kim, Sang-Hyun,Suh, In-Bum,Kim, Woo Jin,Jung, Jae-Wan,Yuk, Jong seol,Kim, Young-Myeong,Ha, Kwon-Soo WILEY-VCH Verlag 2006 Proteomics Vol.6 No.24
<P>We investigated the potential use of a spectral surface plasmon resonance (SPR) biosensor in a high-throughput analysis of mumps virus and a mumps virus-specific mAb on the arrays of a cationic polyelectrolyte, poly(diallyldimethylammonium chloride) (PDDA). The PDDA surface was constructed by electrostatic adsorption of the polyelectrolyte onto a monolayer of 11-mercaptoundecanoic acid (MUA). Poly-L-lysine was also adsorbed onto the MUA monolayer and compared with the PDDA surface in the capacity of mumps virus immobilization. The PDDA surface showed a higher adsorption of mumps virus than the poly-L-lysine surface. The SPR signal caused by the virus binding onto the PDDA surface was proportional to the concentration of mumps virus from 0.5 × 10<SUP>5</SUP> to 14 × 10<SUP>5</SUP> pfu/mL. The surface structure of the virus arrays was visualized by atomic force microscopy. Then, a dose-dependent increase in the SPR signal was observed when various concentrations of the antimumps virus antibody in buffer or human serum were applied to the virus arrays, and their interaction was specific. Thus, it is likely that the spectral SPR biosensor based on the cationic polyelectrolyte surface may provide an efficient system for a high-throughput analysis of intact virus and serodiagnosis of infectious diseases.</P>
스트렙토조토신 유도성 당뇨쥐의 췌장 선포세포에서 Cholecystokinin이 유도한 Calcium Signal의 변화
김명준 ( Kim Myeong Jun ),류경렬 ( Lyu Gyeong Lyeol ),성종호 ( Seong Jong Ho ),민도식 ( Min Do Sig ),이덕주 ( Lee Deog Ju ),윤신희 ( Yun Sin Hui ),한상준 ( Han Sang Jun ),조양혁 ( Jo Yang Hyeog ),김명석 ( Kim Myeong Seog ) 대한소화기학회 2003 대한소화기학회지 Vol.42 No.6
Background/Aims: Pancreatic acini of streptozotocin (STZ)-induced diabetic rats release amylase less than normal acini on cholecystokinin (CCK) stimulation. Pancreatic enzyme secretion has been closely related to the intracellular calcium concentration ([Ca2+]i) of the acinar cell. In the present study, sequential changes of the intracellular calcium signal which probably underlie the altered enzyme secretion in response to CCK-8 were investigated using pancreatic acini from diabetic rats. Methods: Diabetic rats were prepared by single intravenous injection of STZ (70 mg/kg). Stimulating experiments with CCK-8 were performed 7 days later. Pancreatic acini were isolated by collagenase digestion. Amylase release and [Ca2+]i were measured by colorimethod and calcium imaging, respectively. The geometry of intracellular calcium signal was analyzed. Results: Normal acini exhibited concentration-dependent [Ca2+]i increase and regular oscillatory calcium signal on CCK-8 stimulation. Amylase release was also concentration-dependent. However, diabetic acini showed significantly less [Ca2+]i increase, prolonged time to peak [Ca2+]i, decreased calcium spikes number, and decreased amylase release compared with normal acini. The decreased [Ca2+]i in diabetic acini was restored significantly by insulin treatment. Conclusions: Relatively decreased amylase release in diabetic pancreatic acini in response to CCK, appears to be associated with altered calcium signal due to insulin deficiency. (Korean J Gastroenterol 2003;42:519-526)
내시경으로 관찰된 식도 병변의 발생과 경비위관 거치의 상관관계 경피 내시경하 위루술을 시행한 185예의 임상적 고찰
김한숙 ( Kim Han Sug ),동석호 ( Dong Seog Ho ),정경환 ( Jeong Gyeong Hwan ),채명종 ( Chae Myeong Jong ),한요셉 ( Han Yo Seb ),정용희 ( Jeong Yong Hui ),이병욱 ( Lee Byeong Ug ),김효종 ( Kim Hyo Jong ),김병호 ( Kim Byeong Ho ),장 대한소화기학회 2003 대한소화기학회지 Vol.42 No.6
Background/Aims: Percutaneous endoscopic gastrostomy (PEG) is a method widely used for long-term enteral nutrition in dysphagia. Mostly, it is preceded by nasogastric intubation (NI) for short-term enteral nutrition; endoscopic findings associated with NI are encountered during PEG. The purpose of this study was to discuss such findings and to delineate a relationship between these findings, especially esophageal lesions and the duration of NI. Methods: This study involved 185 individuals who had undergone PEG at Kyung Hee Medical Center from January 1999 to May 2002. The medical records were examined retrospectively. Results: The dysfunction of the CNS comprised 98.4% of the causes of dysphagia. The duration of NI was 15.2 weeks on average, with median value of 8.7 weeks, indicating that PEG was performed relatively soon. Endoscopic findings revealed esophagitis in 63 cases, esophageal ulcers in 27 and active bleedings in another 10. The incidence of esophageal lesions was shown to be higher in subjects with duration of NI under 12 weeks than in those with duration over 12 weeks (p=0.032). Conclusions: PEG was carried out in many cases during the early stages of dysphagia, and NI-associated esophageal lesions appeared to be more prevalent within 12 weeks of NI duration. These results may be of help in deciding the timing of PEG. (Korean J Gastroenterol 2003;42:461-467)