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Minah Jeong,Kwang Yeon Lee,Hyeon Gyu Lee 한국식품과학회 2021 한국식품과학회지 Vol.53 No.1
The physicochemical properties of deodeok (Codonopsis lanceolate) was investigated in relation to the different steaming time and cycles of steaming and drying (S/D). Additionally, the quality characteristics of Makgeolli with different amount (0-0.45%) of steaming and drying deodeok (SD) were measured comparison to non-steaming and drying deodeok (NSD). L* values of deodeok tended to decrease as the number of S/D cycles and steaming times increased, while BI showed the opposite trend for L* values. Reducing sugar increased significantly from 1 to 3 S/D cycles and decreased thereafter (p<0.05). Also, processed with steaming for 4 h and 5 S/D cycles had the highest antioxidant properties. Principal component analysis (PCA) revealed that the S/D process notably influenced the properties of deodeok. Quality characteristics of Makgeolli showed that 0.45% SD resulted in higher antioxidant properties than control or NSD.
Lee Won,Park Hyungyou,Moon Sun-Young,Oh Sanghoon,Lee Junhee,Kim Minah,Kwon Jun Soo 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.6
Objective The cerebello-thalamic tract is the only efferent white matter (WM) bundle of the cerebellum that connects the cerebellum to the thalamus and has recently attracted much attention in obsessive-compulsive disorder (OCD) with its integral role in higher order cognitive functions commonly impaired in OCD patients. Previous neuroimaging studies have shown that the cerebello-thalamic circuit is functionally impaired in OCD patients. However, the WM integrity of the cerebello-thalamic tract in OCD, which may underly functional abnormalities of the cerebello-thalamic circuit, is not yet sufficiently understood. Therefore, the current study aimed to elucidate whether compromised cerebello-thalamic WM integrity is observed in medication-free OCD patients.Methods In this study, diffusion tensor imaging was acquired from 106 medication-free OCD patients and 105 matched healthy controls (HCs). Probabilistic tractography was then used to reconstruct the cerebello-thalamic tract with accurate anatomical features. Three diffusion indices (fractional anisotropy, FA; mean diffusivity, MD; radial diffusivity, RD) were measured from the reconstructed bilateral cerebello-thalamic tract and then compared between groups.Results We found that patients with OCD showed significantly increased MD and RD in the right cerebello-thalamic tract compared to HCs, and there was no difference in FA between groups.Conclusion Our findings may indicate the underlying structural abnormalities of the dysfunctional cerebello-thalamic circuit in OCD patients. Therefore, our findings are expected to provide novel insights into the pathophysiology of OCD on the cerebello-thalamic WM architecture, extending our knowledge from the existing functional neurobiological model of OCD.
Settling and Filtering Processes for Treatment of Fine Suspended Solidsand Soluble Heavy Metals
Minah Oh(오민아),Wonki Kim(김원기),Seungjin Oh(오승진),Dukmin Kim(김덕민),SangHoon Lee(이상훈),Jai-Young Lee(이재영) 한국지반신소재학회 2013 한국토목섬유학회 학술발표회 Vol.2013 No.11
Fine suspended solids and heavy metals generated effluence from mine drainage could destroy environment as the aesthetic landscapes, and depreciate water quality. Therefore, the purpose of this research is focused on process development applied the actual field for controlling fine suspended solids and heavy metals, and so lab-scale test was performed for inducement of basic data. The mine drainage used in this research was sampled in H. mine located Jeongseon-gun, Gangwon-do. Concentration of suspended soil, arsenic, iron and manganese was exceeded the standard of contaminant limitation for the clean water, and particle size of suspended solid was less than 10 μm as fine particle. Although hydraulic retention time of mine drainage for effective settling was required more than 6 hours, hydraulic retention time would be increased in winter season when the settling efficiency could be reduced because of viscosity decreasing. Moreover, installed inclination plate helped to increase settling efficiency of suspended solid about 30 %. Filtering media that was the most effective removal of suspended solids and heavy metal was indicated granular activated carbon of 1~2 mm was the optimal size.
Lee, Tae-Kyeong,Park, Joon Ha,Ahn, Ji Hyeon,Kim, Hyunjung,Song, Minah,Lee, Jae-Chul,Kim, Jong Dai,Jeon, Yong Hwan,Choi, Jung Hoon,Lee, Choong Hyun,Hwang, In Koo,YAN, Bing-Chun,Won, Moo-Ho,Kang, Il Jun Elsevier 2019 Chinese journal of natural medicines Vol.17 No.6
<P><B>Abstract</B></P> <P>To examine the effects of <I>Populus tomentiglandulosa</I> (PT) extract on the expressions of antioxidant enzymes and neurotrophic factors in the cornu ammonis 1 (CA1) region of the hippocampus at 5 min after inducing transient global cerebral ischemia (TGCI) in gerbils, TGCI was induced by occlusion of common carotid arteries for 5 min. Before ischemic surgery, 200 mg·kg<SUP>−1</SUP> PT extract was orally administrated once daily for 7 d. We performed neuronal nuclear antigen immunohistochemistry and Fluoro-Jade B staining. Furthermore, we determined <I>in situ</I> production of superoxide anion radical, expression levels of SOD1 and SOD2 as antioxidant enzymes and brain-derived neurotrophic factor (BDNF) and insulin-like growth factor I (IGF-I) as neurotrophic factors. Pretreatment with 200 mg·kg<SUP>−1</SUP> PT extract prevented neuronal death (loss). Furthermore, pretreatment with 200 mg·kg<SUP>−1</SUP> PT extract significantly inhibited the production of superoxide anion radical, increased expressions of SODs and maintained expressions of BDNF and IGF-I. Such increased expressions of SODs were maintained in the neurons after IRI. In summary, pretreated PT extract can significantly increase levels of SODs and protect the neurons against TGCI, suggesting that PT can be a useful natural agent to protect against TGCI.</P>