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      • KCI등재

        Application of ZnO and TiO2 nanoparticles coated onto montmorillonite in the presence of H2O2 for efficient removal of cephalexin from aqueous solutions

        Rasoul Khosravi,Ahmad Zarei,Mohsen Heidari,Ali Ahmadfazeli,Mehdi Vosughi,Mehdi Fazlzadeh 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.4

        This study considers the feasibility of uptake of cephalexin, an emerging contaminant, from aqueous solutions by using green local montmorillonite (GLM), montmorillonite coated with ZnO (ZnO/GLM) and montmorillonite coated with TiO2 (TiO2/GLM) in the presence of H2O2. Batch adsorption experiments were carried out as a function of pH, initial concentration of the cephalexin, adsorbent dosage, contact time, and temperature. Finally, the adsorbents were characterized by XRD, SEM and FTIR analyses. XRD patterns showed dramatic changes in the adsorbents after loading with the nanoparticles, confirming successful placing of the nanoparticles onto GLM. The GLM mineral surface after nanoparticle loading appears to be fully exposed and more porous with irregular shapes in particles diameters of 1-50 microns. FTIR analyses also confirmed dramatic changes in surface functional groups after modification with these nanoparticles. The results showed that the removal efficiency of cephalexin was better at lower pH values. Totally, the removal efficiency increased with increase in adsorbent dosage and contact time and decreased with concentration and temperature increase. The thermodynamics values of Go and Ho revealed that the adsorption process was spontaneous and exothermic. In isotherm study, the maximum adsorption capacities (qm) were obtained to be 7.82, 17.09 and 49.26mg/g for GLM, ZnO/GLM and TiO2/GLM, respectively. Temkin constant (BT) showed that adsorption of cephalexin from solution was exothermic for all three adsorbents.

      • KCI등재

        Assessment of Spatial Distribution and Temporal Trends of Temperature in Iran

        Asakereh Hossein,Khosravi Younes,Doostkamian Mehdi,Solgimoghaddam Mustafa 한국기상학회 2020 Asia-Pacific Journal of Atmospheric Sciences Vol.56 No.4

        Temperature is one of the most important elements of climate, which undergoes temporal and spatial changes under the influence of local and external factors. These changes can cover micro and macroclimate areas as well as short to long-term periods. Therefore, in the present study, the spatial patterns of temperature change in Iran over the past half-century are discussed. To this end, average annual temperature of 383 synoptic stations in Iran during 50 years (1961–2010) were collected from Iran Meteorological Organization. Linear regression and local Moran’s I were used to analyze the trend of changes and the spatial patterns respectively. The results of intra-decade changes in temperature showed that the average temperature of Iran has increased significantly in recent decades, and have experienced less significant daily fluctuations at the same time. Results obtained from analysis of intra-decade temperature change trend showed that temperature has dramatically increased as a result of rises in mean temperature levels in recent decades, such that in the fourth (1991 to 2000) and fifth decade (2001 to 2010) the temperature variation trend has increased by 0.17 and 0.1 respectively, while the temperature of Iran in the first and third decade has declined by −0.03. The results obtained from analysis of spatial pattern of intra-decade temperature variation showed that spatial temperature pattern in Iran is mostly influenced by local factors such as latitudes variations. Generally, with increasing latitude in Iran, the temperature decreases. The temperature in the mountainous areas (negative spatial autocorrelation), southern parts, and areas around Persian Gulf, follow a high spatial pattern (positive spatial autocorrelation) due to lower latitudes and special condition of greenhouse gas emission. However, in recent decades, the positive spatial pattern zones have increased significantly as a result of upward temperature trends.

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        Investigating the expression pattern of the angiopoietin-Tie system in ALL and its correlation with baseline characteristics

        Saeed Zaka Khosravi,Samira Molaei Ramshe,Mehdi Allahbakhshian Farsani,Saeed Solali,Mohammadreza Moonesi,Majid Farshdousti Hagh 대한혈액학회 2021 Blood Research Vol.56 No.2

        Background Acute lymphoblastic leukemia (ALL) is the most common type of leukemia in children. Several environmental and genetic factors are known to be involved in its development and progression. The angiopoietin-Tie system is one of the most critical factors in angiogenesis, and its possible role in solid tumors and leukemia has been previously investigated. In this study, we examined the expression of these genes in ALL patients (early pre-B-ALL and pre-B-ALL) and compared them with normal samples. Methods Bone marrow samples were collected from 40 patients (aged 0‒19 yr) newly diagnosed with early pre-B-ALL or pre-B-ALL using molecular and flow cytometric tests and from 15 control individuals. For molecular tests, RNA extraction and cDNA synthesis were performed, and Ang1, Ang2, Ang4, Tie1, and Tie2 gene expression was examined by real-time polymerase chain reaction. Results Ang2, Tie1, and Tie2 gene expression were significantly increased in patients with ALL, whereas Ang1 gene expression was decreased. The Ang4 gene did not show significant expression changes between the two groups. Conclusion Changes in the expression of the Ang-Tie system indicate a possible role of angiogenesis in ALL prognosis. Moreover, such changes can be considered as potential diagnostic biomarkers or therapeutic targets.

      • KCI등재

        A Porous Sodium Alginate-CaSiO3 Polymer Reinforced with Graphene Nanosheet: Fabrication and Optimality Analysis

        Shahin Foroutan,Mohammad Hashemian,Mehdi Khosravi,Mazyar Ghadiri Nejad,Azadeh Asefnejad,Saeed Saber-Samandari,Amirsalar Khandan 한국섬유공학회 2021 Fibers and polymers Vol.22 No.2

        Bone regeneration is a growing and relatively effective treatment in most bone disease treatments. Adverse effectsassociated with conventional transplantation techniques have led to advanced bone tissue engineering. The purpose of thisstudy is to produce a bone scaffold, made of sodium alginate (Na-Alg) based scaffold, with the addition of wollastonitegraphenenanosheet (WS-GS) with similar mechanical properties to normal bone. First, the Na-Alg-WS-GS nanocompositesare fabricated using freeze-drying technique in which GS is used as additives with different weight percentages (0, 1, 2 and3 wt%). The fabricated nanocomposite scaffolds are tested and analyzed by X-ray diffraction (XRD) and scanning electronmicroscopy (SEM) analyzes. The maximum tensile strength, lowest decrease in sample area and stress yield is tested usingmechanical testing. Then, the biological response in the biological environment, pH and weight changes after immersion insimulated body fluid (SBF) and phosphate buffered saline (PBS) is determined. The results show that the sample with 1 wt%GS has an appropriate capacity for reconstitution in the biological solution. The SEM shows an appropriate porosity of thescaffolds and a uniform distribution of GS in the polymeric matrix. The SEM images shows that as the amount of GSincreases, the swelling capacity of the nanocomposites rises, regarding the weak bonding of GS and polymeric matrix. Additional amount of GS leads to increase in the tensile strength with the sample containing 1 wt%, however increasing ofGS may decreases the mechanical performance of the structure. To gain the optimal combination of scaffold with the bestmechanical and biological properties, the Global Criterion Method (GCM) is utilized. The obtained results show that theprepared nanocomposites are suitable for further development in tissue engineering and can be suitable for the bonesubstitutes application with desirable mechanical performance.

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