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Review : Graft-versus-Leukemia Effect of Nonmyeloablative Stem Cell Transplantation
( Masahiro Imamura ),( Junji Tanaka ) 대한내과학회 2009 The Korean Journal of Internal Medicine Vol.24 No.4
Nonmyeloablative stem cell transplantation (NST) is increasingly used with beneficial effects because it can be applied to older patients with hematological malignancies and those with various complications who are not suitable for conventional myeloablative stem cell transplantation (CST). Various conditioning regimens differ in their myeloablative and immunosuppressive intensity. Regardless of the type of conditioning regimen, graft-versus-host disease (GVHD) in NST occurs almost equally in CST, although a slightly delayed development of acute GVHD is observed in NST. Although graft-versus-hematological malignancy effects (i.e., graft-versus-leukemia effect, graft-versus-lymphoma effect, and graft-versus-myeloma effect) also occur in NST, completely eradicating residual malignant cells through allogeneic immune responses is insufficient in cases with rapidly growing disease or uncontrolled progressive disease. Donor lymphocyte infusion (DLI) is sometimes combined to support engraftment and to augment the graft-versus-hematological malignancy effect, such as the graft-versus-leukemia effect. DLI is especially effective for controlling relapse in the chronic phase of chronic myelogenous leukemia, but not so effective against other diseases. Indeed, NST is a beneficial procedure for expanding the opportunity of allogeneic hematopoietic stem cell transplantation to many patients with hematological malignancies. However, a more sophisticated improvement in separating graft-versus-hematological malignancy effects from GVHD is required in the future. (Korean J Intern Med 2009;24:287-298)
New Geo-economic Thinking on North Korea in Japan
Masahiro Matsumura 통일연구원 2008 International journal of korean unification studie Vol.17 No.2
Japan’s North Korea policy is currently based on solid strategic calculation, and Tokyo will most likely adhere to the six-party talks process for the resolution of the nuclear, ballistic missile, and abduction issues. However, adherence to this policy is neither static nor permanent. Tokyo will be forced to reformulate a new approach if the talks process makes significant progress, or if the Pyongyang regime collapses abruptly, replaced by a new one satiated with the status quo that involves lowering the tensions centered on North Korea. This paper analyzes major factors pushing the Japanese government to their adoption of a geo-economic approach to North Korea, something which represents a major shift from the current thinking and policy approach. The Japanese public has recently been exposed to an alternative perspective, critical of U.S. North Korea policy, particularly in regard to the recent u-turn in policy toward appeasement and the growing skepticism of the U.S. allegation regarding Pyongyang’s counterfeiting activities. The Japanese public has also become gradually aware of growing U.S.-European competition in direct investment in North Korean underground resources and of the latent Japanese edge in that competition. This paper discusses the prospects for a geo-economic regional power game and an evolving Japanese geo-economic policy approach.
Semantic Segmentation with Rgbd Camera and Real-time 2D Mapping in Fields for Robot Mower
( Masahiro Moriya ),( Yutaka Kaizu ),( Kenji Imou ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1
Mowing is burdensome and automation by the robot mower is expected. For autonomous running of the robot mower, the accurate information of fields with various types of objects is necessary. In this research, we developed a real-time outdoor 2D mapping method based on semantic segmentation using RGBD camera for autonomous running of robot mower. In our method, first, pixel-wise classification image is obtained from RGB-D image using semantic segmentation, which is a technique of image processing by deep convolutional neural network (DCNN), and using the classification image and the depth image, the environmental information about the location and the type of objects in the surroundings is obtained. At the same time, the state (position, attitude, etc.) is estimated from output of GNSS receiver and Inertial Measurement Unit (IMU) using Extended Kalman Filter (EKF). By combining the environmental information and the state, 2D map is created in real-time. To verify our method, we used the differential driven four-wheel vehicle (with two driving wheels, two driven wheels) imitating an actual mower (with four driving wheels). The vehicle has an RGBD camera, a GNSS receiver, IMU and a control computer. As a result, the vehicle properly classified the surrounding objects and 2D map was created in real time. By using the map obtained by our method, autonomous running of the robot mower can be performed even in fields with various types of objects.
Advanced powder processes for chemical applications
( Masahiro Inoki ) 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.1
Composing technology has opened the door for developing new functionalities as well as new materials for its ability to create composite particles using ultra-fine particles with different properties that could never be achieved with single components. For this reason, there are high hopes for Nano Particle Technology to be a breakthrough for further advancements in Powder Technology. In this presentation, we will introduce mainly two machines that our company has developed; Single/Multi-component oxidized Nano Particle Synthesizer “Nano Creator (FCM)” and Mechanical Dry Particle Composing Machine “Nobilta (NOB)”. We will review the technical features for each machine as well as its performance and applications respectively.