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RISS 인기검색어
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- 저자 : Liu Pei (검색결과 225 건)
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Shu-Tsen Liu(Shu-Tsen Liu),Sheng-Che Lin(Sheng-Che Lin),Jane Pei-Chen Chang(Jane Pei-Chen Chang),Kai-Jie Yang(Kai-Jie Yang),Che-Sheng Chu(Che-Sheng Chu),Chia-Chun Yang(Chia-Chun Yang),Chih-Sung Liang( 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.1
There is growing evidence that the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with increased risks of psychiatric sequelae. Depression, anxiety, cognitive impairments, sleep disturbance, and fatigue during and after the acute phase of COVID-19 are prevalent, long-lasting, and exerting negative consequences on well-being and imposing a huge burden on healthcare systems and society. This current review presented timely updates of clinical research findings, particularly focusing on the pathogenetic mechanisms underlying the neuropsychiatric sequelae, and identified potential key targets for developing effective treatment strategies for long COVID. In addition, we introduced the Formosa Long COVID Multicenter Study (FOCuS), which aims to apply the inflammation theory to the pathogenesis and the psychosocial and nutrition treatments of post-COVID depression and anxiety.
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Liying Dong(Liying Dong),Shufang Liu(Shufang Liu),Jing Li(Jing Li),Didier Tharreau(Didier Tharreau ),Pei Liu(Pei Liu),Dayun Tao(Dayun Tao),Qinzhong Yang(Qinzhong Yang) 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.6
Rice blast is one of the most destructive diseases of rice worldwide, and the causative agent is the filamentous ascomycete Magnaporthe oryzae. With the successful cloning of more and more avirulence genes from M. oryzae, the direct extraction of M. oryzae genomic DNA from infected rice tissue would be useful alternative for rapid monitoring of changes of avirulence genes without isolation and cultivation of the pathogen. In this study, a fast, low-cost and reliable method for DNA preparation of M. oryzae from a small piece of infected single rice leaf or neck lesion was established. This single step method only required 10 min for DNA preparation and conventional chemical reagents commonly found in the laboratory. The AvrPik and AvrPi9 genes were successfully amplified with the prepared DNA. The expected DNA fragments from 570 bp to 1,139 bp could be amplified even three months after DNA preparation. This method was also suitable for DNA preparation from M. oryzae strains stored on the filter paper. All together these results indicate that the DNA preparation method established in this study is reliable, and could meet the basic needs for polymerase chain reaction-based analysis of M. oryzae.
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Elastography for Breast Cancer Diagnosis: a Useful Tool for Small and BI-RADS 4 Lesions
Liu, Xue-Jing,Zhu, Ying,Liu, Pei-Fang,Xu, Yi-Lin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24
The present study aimed at evaluating and comparing the diagnostic performance of B-mode ultrasound (US), elastography score (ES), and strain ratio (SR) for the differentiation of breast lesions. This retrospective study enrolled 431 lesions from 417 in-hospital patients. All patients were examined with both conventional ultrasound and elastography. Two experienced radiologists reviewed ultrasound and elasticity images. The histopathologic result obtained from ultrasound-guided core biopsy or operation excisions were used as the reference standard. Pathologic examination revealed 276 malignant lesions (64%) and 155 benign lesions (36%). A cut-off point of 4.15 (area under the curve, 0.891) allowed significant differentiation of malignant and benign lesions. ROC (receiver-operating characteristic) curves showed a higher value for combination of B-mode ultrasound and elastography for the diagnosis of breast lesions. Conventional ultrasound combined elastography showed high sensitivity, specificity, and accuracy for group II lesions (10mm<lesion diameter ${\leq}20mm$). Elastography combined with conventional ultrasound show high specificity and accuracy for differentiation of benign and malignant breast lesions. Elastography is particularly important for the diagnosis of BI-RADS 4 and small breast lesions.
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Liu, Jing,Liu, Pei-Fang,Li, Jun-Nan,Qing, Chun,Ji, Yu,Hao, Xi-Shan,Zhang, Xue-Ning Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Background: A dense breast not only reduces the sensitivity of mammography but also is a moderate independent risk factor for breast cancer. The percentage of Western women with fat breast tissue is higher aged 40 years or older. To a certain extent, mammography as a first choice of screening imaging method for Western women of this group is reasonable. Hitherto, the frequency and age distribution of mammographic breast density patterns among Chinese women had not been characterized. The purpose of this study was to investigate the frequency and age distribution of mammographic breast density patterns among a group of Chinese screening women and breast cancer patients in order to provide useful information for age-specific guidelines for breast cancer screening in Chinese women. Methods: A retrospective review of a total of 3,394 screening women between August and December 2009 and 2,527 breast cancer patients between July 2011 and June 2012 was conducted. Descriptive analyses were used to examine the association between age and breast density. The significance of differences of breast density between the screening women and the breast cancer patients was examined using nonparametric tests. Results: There was a significant inverse relationship between age and breast density overall (r=-0.37, p< 0.01). Breast density of the breast cancer patients in the subgroups of 40-49 years old was greater compared with that of the screening women, the same in those aged 50-54 years and in those 55 years old or older, less than in the screening group. Conclusions: With regard to the Chinese women younger than 55 years old, the diagnostic efficiency of breast cancer screening imaging examinations may be potentially improved by combining screening mammography with ultrasound.
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Enhanced Morris for the extraction of significant parameters in high-dimensional design optimization
Pei Yuan,Jin Cheng,Zhenyu Liu,Daxin Liu,Jianrong Tan 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.11
The traditional Morris method cannot ensure the consistent extraction of significant parameters because its random sampling strategy often leads to an improper coverage of the input space, especially when the number of sample points is small. To overcome the drawbacks, we developed an improved sampling strategy to enhance the performance of Morris method based on Latin hypercube sampling (LHS) with the idea of Central composite design (CCD) and a fluctuant step to generate a more uniform points set. A comparison on the results of a numerical example obtained by the enhanced Morris, the traditional methods and CCS-Morris demonstrated that the former had a much better performance. The application of the enhanced Morris method in the high-dimensional optimization of a compressor shell with 15 design parameters aimed at increasing its natural frequencies and keeping its mass relatively light demonstrates that the method is effective and applicable in engineering design.
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Dynamic reliability of structures: the example of multi-grid composite walls
Liu, Pei,Yaoa, Qian-Feng Techno-Press 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.36 No.4
Based on damage accumulation of multi-grid composite walls, a method of dynamic reliability estimations is proposed. The multi-grid composite wall is composed of edge frame beam, edge frame columns, grid beams, grid columns and filling blocks. The equations including stiffness, shear forces at filling blocks cracking and multi-grid composite walls yielding, ultimate displacement, and damage index are obtained through tests of 13 multi-grid composite wall specimens. Employing these equations in reliability calculations, procedures of dynamic reliability estimations based on damage accumulation of multi-grid composite walls subjected to random earthquake excitations are proposed. Finally the proposed method is applied to the typical composite wall specimen subjected to random earthquake excitations which can be specified by a finite number of input random variables. The dynamic reliability estimates, when filling blocks crack under earthquakes corresponding to 63% exceedance in 50 years and when the composite wall reach limit state under earthquakes corresponding to 2-3% exceedance in 50 years, are obtained using the proposed method by taking damage indexes as thresholds. The results from the proposed method which show good agreement with those from Monte-Carlo simulations demonstrate the proposed method is effective.
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