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김소연,박동진,권오성,임채영,김판경,이상화,김창진 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2
제주도지역, 충청남도 서해안지역, 강원도 및 충청북도 자연 동굴지역, 그리고 충청북도 청원군 등지에서 채집한 205점의 토양시료로부터 분리된 총 1,322주의 방선균을 대상으로 Eschericia coli KCTC 1924, Salmonella typhimurium KCTC 1926, Staphylococcus aureus KCTC 1926, Staphylococcus aureus KCTC 1928, Candida albicans KCTC 1940등 5종의 시험균주에 대하여 항균활성을 조사하였다. 액체배양을 위해서는 G.S.S(glucose-soybean meal-starch) 배지와 fish meal 배지등 2종류의 배지를 사용하였으며 그 결과를 균분리원 지역별, 배지별, 시험균주별, 그리고 방선균 종류별로 비교하였다. It is well known that actinomycetes would be useful for screening of biologically active compounds. Not only to isolate diverse actinomycete strains but to ferment those strains effectively would be important. Seven hundred and forty six strains were isolated from Cheju province, 216 strains were from Chungnam province, 158 strains were from the natural caves at Chungbuk and Kangwon provinces and 202 strains were from Chungwon area at Chungbuk province. All of these 1,322 strains were fermented on a small scale using two different media and tested for their antimicrobial activities against four bacterial strains and one yeast strain. As the result, 12.3% of those isolates were active against Staphylococcus aureus KCTC 1916, 7.6% were Staphylococcus aureus KCTC 1928, 3.9% were Eschericia coli KCTC 1924, 3.0% were Canida albicans KCTC 1940, and 2.2% were Salmonella typhimurium KCTC 1926. About 40% of those isolates showed antimicrobial activities at both two media but the others showed at either one. According to the genus of isolated strains, Streptomyces and Micromonospora showed activities with higher frequencies than others.
In-situ Production Analysis of Composite Precast Concrete Members of Green Frame
Lim, Chae-Yeon,Joo, Jin-Kyu,Lee, Goon-Jae,Kim, Sun-Kuk The Korean Institute of Building Construction 2011 한국건축시공학회지 Vol.11 No.5
Recently, there have been many cases in which the difficulty of repair and replacement of principal elements in the bearing wall structure for apartment buildings, which is a major part of apartment buildings in Korea, has led to the reconstruction of buildings rather than their remodeling. To address this problem, the Korea government now allows a floor area ratio of up to 20 %, and has relaxed the building height limits to encourage the use of a rahmen structure instead of a bearing wall structure. However, since reinforced concrete rahmen structures have many problems, including higher floor height and greater construction cost, a great deal of research into rahmen composite precast concrete structures have been conducted. Green Frame, one of the developed prototypes, is expected to provide economic benefits through in-situ production for precast concrete column and beam. For in-situ production of composite precast concrete members, a detailed plan for production, curing, and installation is needed. However, it needs to be confirmed that the space is sufficient to produce the precast concrete members on-site before planning those activities. Therefore, this study proposes in-situ production analysis of composite precast concrete members of Green Frame with the evaluation of structural safety and available area on the parking structure. The result of this study shows that the in-situ production of precast concrete members is possible through a case study.
Automatic Arrangement Algorithm for Tower Cranes Used in High-rise Apartment Buildings
Lim, Chae-Yeon,Kim, Sun-Kuk,Seo, Deok-Seok,Son, Ki-Young The Korean Institute of Building Construction 2012 한국건축시공학회지 Vol.12 No.3
On most construction sites, the arrangement of tower cranes is decided by site engineers based on their own experience, which can cause cost overruns and delays in the lifting work. Although many researchers have conducted studies on tower crane arrangement using computer modeling and knowledge-based expert systems as well as mathematical models, no research has aimed to develop an algorithm to identify an optimum solution among several alternatives for installation areas of tower cranes satisfying the conditions of lifting work. The objective of this study is to develop an automatic arrangement algorithm for tower cranes used in high-rise apartment construction. First, as a new concept, a possible installation area of tower cranes was suggested. Second, after proposing several alternatives based on the installation points suggested in this study, an algorithm analyzing the economic feasibility of tower cranes was developed considering the rental, installation and removal costs. Third, a case study was conducted to prove the validity of the developed algorithm for selecting and installing an effective set of tower cranes at minimum cost.
Lim Chae-Yeon,Kim Deuk-Su,Kang Yangjoo,Lee Ye-Rin,Kim Kibum,Kim Do Sun,Kim Moon-Soo,Ko Kisung 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.6
Epidermal cell adhesion molecule (EpCAM) is a tumor-associated antigen (TAA), which has been considered as a cancer vaccine candidate. The EpCAM protein fused to the fragment crystallizable region of immunoglobulin G (IgG) tagged with KDEL endoplasmic reticulum (ER) retention signal (EpCAM-FcK) has been successfully expressed in transgenic tobacco (Nicotiana tabacum cv. Xanthi) and purified from the plant leaf. In this study, we investigated the ability of the plant-derived EpCAM-FcK (EpCAM-FcKP) to elicit an immune response in vivo. The animal group injected with the EpCAM-FcKP showed a higher differentiated germinal center (GC) B cell population (~9%) compared with the animal group injected with the recombinant rhEpCAM-Fc chimera (EpCAM-FcM). The animal group injected with EpCAM-FcKP (~42%) had more differentiated T follicular helper cells (Tfh) than the animal group injected with EpCAM-FcM (~7%). This study demonstrated that the plant-derived EpCAM-FcK fusion antigenic protein induced a humoral immune response in mice.
국내 대학의 창의·디자인 교양 교육 현황 및 방향성 연구
임채연(Chae Yeon Lim) 한국디자인리서치학회 2023 한국디자인리서치 Vol.8 No.3
4차 산업혁명을 선도할 미래 인재 양성을 위한 대학 창의 교육의 중요성이 언급되는 시점이다. 본 연구는 창의·디자인 교육이 지향해야 할 점과 창의 역량 배양을 위해 나아가야 할 방향성 추구를 위한 목적으로 현재 국내 대학에 개설된 창의·디자인 교과 현황 파악을 하고, 더불어 2019년부터 2020년까지 디자인 이론 중심 수업과 디자인 사고를 기반으로 한 문제 해결 활동의 두 종류 실험 수업을 진행하여 연구 결과를 고찰하였다. 연구 결과, 각 대학이 창의 교육의 중요성을 인지하고 있으나, 창의와 관련된 교과목은 다양성이 부족하여 학생들에게 폭넓은 형태의 강좌를 제공하지 못하고 있는 것으로 보인다. 장기적 목표로 학생의 통합적 사고 능력과 창의적 사고력을 함양할 수 있는 지속적이고 체계적인 프로그램의 확대가 필요하다. 창의·디자인 교육의 방향은 다학제적 안목으로 새로운 지식 창출을 위한 융복합 교육과 창의 활동에 따른 미적 체험이 이루어지는 통합적 사고 과정을 주축으로 자기 주도적 학습형태로 지향되어야 한다. It is time to mention the importance of creative education at universities to foster future talents who will lead the fourth industrial revolution. This study identified the current status of creative and design courses currently opened at domestic universities for the purpose of pursuing the goals of creative and design education and the direction to cultivate creative capabilities, and conducted two types of experimental classes based on design theory and design thinking from 2019 to 2020. As a result of the study, each university is aware of the importance of creative education, but it seems that creative-related subjects are not providing a wide range of courses to students due to lack of diversity. As a long-term goal, it is necessary to expand continuous and systematic programs that can cultivate students' integrated thinking skills and creative thinking skills. The direction of creative and design education should be directed in the form of self-directed learning, focusing on convergence education to create new knowledge from a multidisciplinary perspective and an integrated thinking process in which aesthetic experiences are made according to creative activities.
디자인 전공 학생을 대상으로 한 바이오미미크리 디자인 교육 사례 연구
임채연(Chae Yeon Lim) 한국디자인리서치학회 2022 한국디자인리서치 Vol.7 No.4
Designers in the future society should play a competent role in converging technology with various fields through creative thinking to lead industrial development, present future visions, and solve many upcoming problems. The purpose of this study is to expand learners' thinking skills and foster creative thinking through bio-micri design education based on the design thinking process for creative and convergent thinking cultivation required by prospective designers. Accordingly, a two-week project class study was conducted on a first-year design major group at D University in Busan in 2021 to examine educational efficiency and various effects through classes by developing and utilizing processes and design toolkits useful in the bio-micri design curriculum. In order to find out about the various influences that appear in learners, in-depth interviews are conducted and analyzed. As a result of the above study, a positive response was found that ideas were diversified in the bio-micri design curriculum using the design toolkit according to the three-step process developed by this researcher as a class tool. 미래 사회의 디자이너들은 창의적 사고를 통해 기술을 다양한 분야들과 융합하여 산업 발전을 주도하고 미래의 비전을 제시하며, 앞으로 다가오는 많은 문제를 해결하는 데 능력을 발휘할 수 있는 유능한 역할을 담당하여야 한다. 본연구의 목적은 예비 디자이너에게 요구되는 창의적이고 융합적 사고 배양을 위해 디자인 씽킹 프로세스를 기반한 바이오미미크리 디자인 교육을 통해 학습자의 사고력 확장과 창의적 사고 함양을 도모하고자 한다. 그에 따라 바이오미미크리 디자인 교육 과정에 유용한 프로세스와 디자인 툴킷을 개발, 활용하여 수업을 통해 나타나는 교육적 효율성 및 다양한 영향에 대해 고찰하고자 2021년 부산 소재 D 대학의 1학년 디자인 전공 집단을 대상으로 2주간의프로젝트 수업 연구를 진행하였다. 학습자에 나타나는 다양한 영향에 대해 알아보기 위해 사전, 사후 심층 인터뷰를진행하고 이를 분석한다. 이상의 연구 결과, 본 연구자가 개발한 3단계 프로세스에 따른 디자인 툴킷을 수업 도구로활용한 바이오미미크리 디자인 교육 과정에서 아이디어가 다양화되면서 창의적 사고와 아이디어 발상에 도움이 된다는 긍정적 반응이 나타났다.