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Zipeprol 남용환자에서 뇌 단일광자방출 전산화단층촬영술의 임상적 의의
김광원(Kwang Won Kim),최영길(Young Kil Choi),고은미(Eun Mi Koh),김덕윤(Deog Yoon Kim),조대옥(Dai Ok Cho),김재필(Jae Phil Kim),양현인(Hyung In Yang) 대한핵의학회 1993 핵의학 분자영상 Vol.27 No.1
N/A Drug abuse is widespread in worldwide and has been associated with neurologic complication. Zipeprol is one of drugs which been abused for psychological satisfaction in some adolescents. This agent is non-opioid antitussive agent, which is not legally considered as being capable of creating dependence or abuse liability at therapeutic serum levels. But it has been reported that acute or chronic overdose create neurologic complication such as convulsion as well as dependence. Recently we experienced six zipeprol abusers who admitted due to convulsion and variable neurologic symptoms. The aim of our study was to determine the role of Tc-99m- HMPAO brain SPECT in those patients. EEG and brain CT showed no abnormal finding, but brain SPECT showed focal or multiple perfusion abnormalities in frontal, parietal, occipital cortex, basal ganglia, thalamus and especially at temporal cortex. These results suggest that brain SPECT may be a useful diagnostic tool to evaluate the cerebral dysfunction indused by zipeprol abuse.
김광원 ( Kwang-won Kim ) 대한갑상선학회 2010 International Journal of Thyroidology Vol.3 No.2
The prevalence of thyroid nodule has been reported to be from 13 to 67% in the world and from 14 to 41% in Korea. Oh et al. (2010) reported that solid thyroid nodules were found in 39%. The prevalence of thyroid cancer was 2.5% among total subjects, and 6.5% among the subjects with thyroid nodules. The prevalence of papillary thyroid carcinoma (PTC) has increased, but the prevalence of follicular thyroid carcinoma and anaplastic thyroid carcinoma has decreased in Korea between 1980’s and 2000’s. The prevalence of BRAF mutations were reported to be 66∼83% in Korean PTC. The prevalence of ret/PTC rearrangement was 13%, but ras mutations were not detected. Jung et al. (2010) compared the clinicopathologic characteristics of 1,139 papillary thyroid microcarcinoma (PTMC) with those of 1,296 PTC more than 1 cm. Aggressiveness was less frequent in patients with PTMC, but recurrence and mortality rates for PTMC were also significantly lower than those of PTC (p<0.05). The prevalence of PTC variants in Korea was 6.7% and it was much lower than previously reported. The disease-specific survival and recurrence-free survival in classic PTC were not different from those of the favorable variants, but they were higher than those of the aggressive variants (p<0.01).
김광원(Kwang Won Kim),최영길(Young Kil Choi),고은미(Eun Mi Koh),김덕윤(Deog Yoon Kim),김병호(Byung Ho Kim),장영운(Young Woon Chang),장린(Rin Chang),김용봉(Yong Bong Kim) 대한핵의학회 1990 핵의학 분자영상 Vol.24 No.2
N/A Scintigraphic measurement of gastric emptying time has been reported to be influenced by the variation in depth of radionuclide within the stomach. In order to determine the effect of tissue attenuation in the measurement of gastric emptying time, 15 gastric emptying studies were performed with Tc-99m labeled egg sandwiches. Single anterior detector method overestimated the T1/2 by an average of 13% than geometric mean method and the range of overestimation was wide (from -13% to +32%). Therefore, to evaluate the gastric empthying time accurately, methods of attenuation correction are needed.
정상 관동맥 조영상을 갖는 급성 심근경색증 환자의 임상적 특징 및 99mTc - MIBI 심근 SPECT 소견
김광원(Kwang Won Kim),김덕윤(Deog Yoon Kim),박명재(Myung Jae Park),최태열(Tae Youl Choi),강홍선(Heung Sun Kang),조정휘(Chung Whee Choue),김권삼(Kwon Sam Kim),김명식(Myung Shick Kim),송정상(Jung Sang Song),배종화(Jong Hoa Bae) 대한핵의학회 1993 핵의학 분자영상 Vol.27 No.1
N/A Among 64 patients with acute myocardial infarction who underwent coronary angiogrphy, 7 patients (10.9%)showed normal coronary artery. Six patients were men and 1 patient was female. The mean age of patients were 31.1±3.9 years. Among the risk factors of coronary heart disease, smoking was most probable factor in patients with acute myocardial infarction with normal coronary angiography. Tc-99m-MIBI heart SPECT performed 5 of 7 patients and showed that it could be used in diagnosis, localization, extent of infarct area in patients with acute myocardial infarction with normal coronary angiography. But follow up Tc-99m-MIBI heart SPECT study will be needed to define the ability of myocardial viability in this patients.