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Adaptive Reconfigurable Flight Control System Based on Recursive System Identification
Kim, Sung Pil,Kim, You Dan,Kim, Hee Seob,Nam, Chang Ho 서울대학교 항공우주신기술연구소 2001 항공우주신기술연구소 연구보고 Vol.2 No.2
An adaptive reconfigurable control algorithm is proposed for fault aircraft tolerant control. An input-output model is derived from a discrete state-space model. The formulated model has the same structure as the ARX model, and therefore any recursive system identification method can be used. Model following control schemes are applied for reconfigurable control system design. The reference outputs for the system to be followed are generated via the linear optimal control theory. During the recursive adaptive control process, the reference system model is updated periodically. The proposed algorithm is very robust and applicable on real time. To validate the proposed adaptive fault tolerant control algorithm, numerical simulation is performed.
Antibacterial activity of Curcuma longa L. against methicillin-resistant Staphylococcus aureus
Kim, Kang-Ju,Yu, Hyeon-Hee,Cha, Jung-Dan,Seo, Se-Jeong,Choi, Na-Young,You, Yong-Ouk John Wiley Sons, Ltd. 2005 Phytotherapy research Vol.19 No.7
<P>Methicillin-resistant Staphylococcus aureus (MRSA) has been emerging worldwide as one of the most important hospital and community pathogens. Therefore, new agents are needed to treat MRSA associated infections. The present study investigated the antimicrobial activity of ethyl acetate, methanol and water extracts of Curcuma longa L. (C. longa) against MRSA. The ethyl acetate extract of C. longa demonstrated a higher antibacterial activity than the methanol extract or water extract. Since the ethyl acetate extract was more active than the other extracts, the study examined whether the ethyl acetate extract could restore the antibacterial activity of β-lactams and alter the MRSA invasion of human mucosal fibroblasts (HMFs). In the checkerboard test, the ethyl acetate extract of C. longa markedly lowered the MICs of ampicillin and oxacillin against MRSA. In the bacterial invasion assay, MRSA intracellular invasion was significantly decreased in the presence of 0.125–2 mg/mL of C. longa extract compared with the control group. These results suggest that the ethyl acetate extract of C. longa may have antibacterial activity and the potential to restore the effectiveness of β-lactams against MRSA, and inhibit the MRSA invasion of HMFs. Copyright © 2005 John Wiley & Sons, Ltd.</P>
Kim, Min Su,Liu, Ying Dan,Park, Bong Jun,You, Chun-Yeol,Choi, Hyoung Jin Elsevier 2012 Journal of industrial and engineering chemistry Vol.18 No.2
<P><B>Abstract</B></P><P>In order to examine dispersion properties of magnetorheological (MR) fluids, characteristics of its medium oil such as their rheological property and density are being focused in this study. Carbonyl iron (CI) based MR fluid with an aqueous polymeric solution using poly(ethylene oxide) (PEO) as a medium was prepared. MR characteristics as a function of applied magnetic field strength was investigated using a rotational rheometer with MR devices attached, demonstrating that the characteristics of the CI–PEO based MR fluids were affected by a medium viscosity in a steady shear flow.</P>
Berberine의 항생제 내성 확색포도구균에 대한 항미생물 효과
김강주,차정단,김해경,유현희,유용욱,이동근 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.2
Antibiotic-resistant Staphylococcus aureus (S. aureus) emerged in many parts of the world and increased complex clinical problems. Therefore, new agents are needed to treat the antibiotic-resistant S. aureus. Some natural products are candidates of new antibiotic substances. Previous reports showed that the extract of Coptidis Rhizoma and Phellodendri Cortex have antimicrobial effects. The main antibacterial substance of Coptidis Rhizoma and Phellodendri Cortex is berberine. In this study, we examined the antimicrobial activity of berberine to antibiotic-resistant S. aureus. We isolated the 13 strains of antibiotic-resistant S. aureus from the oral cavity of healthy children in a preschool, and investigated the antimicrobial activity of berberine. We examined the effects of berberine on the level of resistance to antibiotic-resistant S. aureus. We observed that the invasion of S. aureus into human gingival fibroblasts was blocked by berberine. Berberine inhibited the growth of antibiotic-resistant S. aureus as a dosw dependent maner. Minimum inhibitory concentration (MIC) of berberine against antibiotic-resistant S. aureus was 50∼100㎍/㎖. The inhibition of S. aureus invasion was depended on the concentration of berberine in human gingival fibroblasts. The MIC of ampicillin against antibiotic-resistant S. aureus was 32㎍/㎖. However, the MIC of ampicillin against antibiotic-resistant S. aureus in the presence of 50㎍/㎖ berberine was 1㎍/㎖. These data indicate that the combination with berberine and β-lactam antibiotics resulted in the synergistic reaction. These results suggest that the berberine may have the antimicrobial activities to antibiotic-resistnat S. aureus, and the mechanism may be the inhibition of growth and intracellular invasion, and alteration of antibiotic-resistance level of antibiotic-resistant S. aureus.