Development of Pongamia pinnata as an Alternative Biofuel Crop - Current Status and Scope of Plantations in India

Kesari, Vigya,Rangan, Latha 한국작물학회 2010 Journal of crop science and biotechnology Vol.13 No.3

Pongamia pinnata is a leguminous tree known for its multipurpose benefits and as a potential source of biodiesel crop. Its added benefits to grow on marginal lands make it a suitable candidate in agro-forestry. These properties support the suitability of this plant for large-scale production required by a sustainable biodiesel industry. While utilizing these species as a source of biodiesel, there is a further need for research and extensive knowledge generation into various areas of production and utilization. The future success of P. pinnata as a sustainable source of biodiesel will heavily depend on an unlimited feed stock supply. This will call for large-scale plantations of clonal stocks of elite genotypes to encourage afforestation programs coordinated both at the central and state levels to cater to the needs of the biodiesel industry. The success rate will rely on the elite planting stock, propagation techniques, and plantation practices and models in making Pongamia cultivation an economically viable proposition.

Genotype-Phenotype correlation of SMN locus genes in spinal muscular atrophy patients from India

Akanchha Kesari,M Mohammed Idris,Giri Raj Chandak,Balraj Mittal 생화학분자생물학회 2005 Experimental and molecular medicine Vol.37 No.3

Spinal muscular atrophy has been classified into four groups based on the age of onset and clinical severity of the disease. Homozygous deletion in SMN1 gene causes the disease but the clinical severity may be modified by copy number of homologous gene SMN2 as wel as the extent of deletion at SMN locus. In the view of scarcity of genotype and phenotype corela-tion data from India, this study has been under-taken to determine that corelation in SMA pa-SMN and NAIP genes and two polymorphic markers C212 and C272 located in this region. Two to four aleles of the markers C212 and C272 were observed in normal indivi-duals. However, majority of Type I patients show-ed only one alele from both markers whereas in Type II and II patients, 2-3 alleles were observed. The SMN2 copy number in our type II patients showed that patients cary 3-5 copies of SMN2 gene. Our results sugest that extent of deletions encompassing H4F5, SMN1, NAIP and copy num-ber of SMN2 gene can modify the SMA pheno-type, thus acounting for the diferent clinical subtypes of the disease.

Development of Pongamia pinnata as an Alternative Biofuel Crop - Current Status and Scope of Plantations in India

Vigya Kesari,Latha Rangan 한국작물학회 2010 Journal of crop science and biotechnology Vol.13 No.3

Pongamia pinnata is a leguminous tree known for its multipurpose benefits and as a potential source of biodiesel crop. Its added benefits to grow on marginal lands make it a suitable candidate in agro-forestry. These properties support the suitability of this plant for large-scale production required by a sustainable biodiesel industry. While utilizing these species as a source of biodiesel, there is a further need for research and extensive knowledge generation into various areas of production and utilization. The future success of P. pinnata as a sustainable source of biodiesel will heavily depend on an unlimited feed stock supply. This will call for large-scale plantations of clonal stocks of elite genotypes to encourage afforestation programs coordinated both at the central and state levels to cater to the needs of the biodiesel industry. The success rate will rely on the elite planting stock, propagation techniques, and plantation practices and models in making Pongamia cultivation an economically viable proposition.

Botulinum toxin injections as salvage therapy is beneficial for management of patellofemoral pain syndrome

( Yuval Kesary ),( Vivek Singh ),( Tal Frenkel ),( Rutenberg ),( Arie Greenberg ),( Shmuel Dekel ),( Ran Schwarzkopf ),( Nimrod Snir ) 대한슬관절학회 2021 대한슬관절학회지 Vol.33 No.-

Purpose: Patellofemoral pain syndrome (PFPS) is a common pathology usually presenting with anterior or retropatellar pain. It is associated with a relative imbalance between the vastus medialis oblique (VMO) and the vastus lateralis (VL) muscles. This can lead to considerable morbidity and reduced quality of life (QOL). This study aims to assess the long-term functional outcome of PFPS treated with VL muscle botulinum toxin A (BoNT-A) injection. Materials and methods: A retrospective review was performed on 26 consecutive patients (31 knees) with a mean age of 50.1 years (± 19.7 years) who were treated with BoNT-A injections to the VL muscle followed by physiotherapy between 2008 and 2015. Pre- and post-treatment pain levels (numerical rating scale, NRS), QOL (SF-6D), and functional scores (Kujala and Lysholm questionnaires) were measured. Demographics, physical therapy compliance, previous surgeries, perioperative complications, and patient satisfaction levels were collected. Results: The mean follow-up time was 58.8 ± 36.4 months. There were significant improvements in all the examined domains. The average pain score (NRS) decreased from 7.6 to 3.2 (P < 0.01), and the Kujala, Lysholm, and SF-6D scores improved from 58.9 to 82.7 (P < 0.001), 56.2 to 83.2 (P < 0.001), and 0.6 to 0.8 (P < 0.001), respectively. Similar delta improvement was achieved irrespective of gender, age, compliance to post-treatment physical therapy, or coexisting osteoarthritis. Patients who presented with a worse pre-treatment clinical status achieved greater improvement. Prior to BoNT-A intervention, 16 patients (18 knees) were scheduled for surgery, of whom 12 (75%, 13 knees) did not require further surgical intervention at the last follow-up. Conclusions: A single intervention of BoNT-A injections to the VL muscle combined with physiotherapy is beneficial for the treatment of patients with persistent PFPS. Level III evidence: Retrospective cohort study.

Biopolymer sodium alginate based titania and magnetite nanocomposites as natural corrosion inhibitors for mild steel in acidic medium

Priya Kesari,G. Udayabhanu,Arpita Roy,Sagar pal 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.122 No.-

Green biopolymeric materials and its hybrid nanocomposites, i.e. sodium alginate grafted polymethylmethacrylatebased titanium dioxide and iron oxide (SA-g-PMMA/TiO2 and SA-g-PMMA/Fe3O4) havebeen explored for the prevention of mild steel’s corrosion in 15% HCl. It is reflected from the electrochemicalimpedance data that SA-g-PMMA/TiO2 exhibits maximum inhibition efficiency of 97.28% followed bySA-g-PMMA/Fe3O4 that gives 96.82% efficiency while the unmodified sodium alginate possess merely84.74% efficiency. The declining trend of inhibition efficiency with rising temperature has been explainedthrough gravimetric studies conducted at 303 K- 333 K. The thermodynamic activation and adsorptionparameters revealed the mixed mode of adsorption of inhibitors over mild steel surface which followLangmuir adsorption isotherm. It has been observed from tafel polarization studies that all studied inhibitorsare mixed type in nature. The surface morphological inspection of the mild steel samples was donethrough FE-SEM and AFM, which revealed the formation of better protective adsorption layer over theexposed metallic surface by the nanocomposites in comparison to sodium alginate alone. In additionto this, the elemental composition of adsorbed film on inhibited mild steel specimens was obtained byXPS technique. Quantum parameters obtained through Density Functional Theory (DFT) further corroboratethe experimental outcomes.

Antimicrobial and Micro Raman Spectroscopy of Selected Zingiberaceae Species from Northeast India

Das, Archana,Kesari, Vigya,Nath, Arpita,Khare, Alika,Rangan, Latha 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.1

Antimicrobial activity of crude rhizome oils from some important members of Zingiberaceae from Northeast India was carried out in the present study. The plants used were Curcuma amada, C. longa, Zingiber moran, and Z. zerumbet. Rhizomes of the four species were collected and rhizome oil was extracted using six different polar and non-polar solvents. The antimicrobial property of the crude oil was studied against human pathogens using disc-diffusion and viability assay. The rhizome oil of all the 24 extracts exhibited potent antimicrobial activity against all pathogenic bacterial and fungal strains tested. Hydrodistilled fractions of the four species studied showed better effect among all solvents. Water extract of Z. moran was found to be the highest effective antimicrobial agent of all. Antibacterial effect of the water fractions was also characterized against Gram-positive and Gram-negative bacteria using micro Raman spectroscopy. This investigation shows that the essential oils from the wild and domestic species of the family Zingiberaceae from Northeast India are a potential source of bioactive compounds with tremendous medicinal, economic, and therapeutic value. The wild and endemic species Z. moran represents an interesting and promising source of plant-derived antimicrobial agent in the development of new drugs against pathogens.

Antimicrobial and Micro Raman Spectroscopy of Selected Zingiberaceae Species from Northeast India

Archana Das,Latha Rangan,Vigya Kesari,Arpita Nath,Alika Khare 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.1

Antimicrobial activity of crude rhizome oils from some important members of Zingiberaceae from Northeast India was carried out in the present study. The plants used were Curcuma amada, C. longa, Zingiber moran, and Z. zerumbet. Rhizomes of the four species were collected and rhizome oil was extracted using six different polar and non-polar solvents. The antimicrobial property of the crude oil was studied against human pathogens using disc-diffusion and viability assay. The rhizome oil of all the 24 extracts exhibited potent antimicrobial activity against all pathogenic bacterial and fungal strains tested. Hydrodistilled fractions of the four species studied showed better effect among all solvents. Water extract of Z. moran was found to be the highest effective antimicrobial agent of all. Antibacterial effect of the water fractions was also characterized against Gram-positive and Gram-negative bacteria using micro Raman spectroscopy. This investigation shows that the essential oils from the wild and domestic species of the family Zingiberaceae from Northeast India are a potential source of bioactive compounds with tremendous medicinal, economic, and therapeutic value. The wild and endemic species Z. moran represents an interesting and promising source of plant-derived antimicrobial agent in the development of new drugs against pathogens.