Islamic Religious Needs in Destination Marketing

Mohamed Kamal Battour,Mohd Nazari Ismail,Idris abdelgawad elhabony 세계문화관광학회 2009 Conference Proceedings Vol.10 No.0

The destination marketers may consider Muslim tourist as a customer segment. In response to that, the supply of Islamic religious attributes for Muslim tourists may lead to increase satisfaction and revisit intension. The success of marketing destinations for Muslim tourists should be guided by observing Islamic teachings (Shariah) in tourism activities. The objective of this study is to explore which Islamic attributes or aspects of the destination are important to the Muslim tourists. The Muslim tourist may need these Islamic religious attributes when he/she is planning to visit a country. Data were collected by two FGDs and 27 interviews with Muslim tourists in July 2009 in Kuala-lumpur, the capital city of Malaysia. Results of the analysis were categorized into two major aspects; physical aspects and environmental aspects. The physical aspect consists of Islamic religious facilities such as, prayer facilities, Halal food, and Islamic entertainments. The environmental aspects related to general environment where the tourists have to practice their activities. Environmental aspect is sometimes uncontrollable but the interviewees are appreciated if there is Islamic environment in the destination where alcohol is not drunk, availability of Islamic dress codes, and availability of general Islamic morality.

A Hybrid DTC-DSC Drive for High Performance Induction Motor Control

Jidin, Auzani,Idris, Nik Rumzi Nik,Yatim, Abdul Halim Mohamed,Sutikno, Tole,Elbuluk, Malik E. The Korean Institute of Power Electronics 2011 JOURNAL OF POWER ELECTRONICS Vol.11 No.5

This paper describes a hybrid induction motor drive system incorporating DTC-hysteresis and Direct Self Control (DSC) schemes to achieve excellent dynamic performance. The control scheme is switched from a circular to a hexagonal flux locus whenever a dynamic condition is encountered. On the other hand, when the motor operates under steady state conditions, a circular flux locus is used. Without major modifications to the simple structure of a basic DTC, hexagonal flux locus operation is established by modifying the flux error status, before it is fed to the look-up table. The feasibility of the proposed hybrid scheme to achieve excellent control performance is verified by experimental results.

Mitochondrial 10398A>G NADH-Dehydrogenase Subunit 3 of Complex I Is Frequently Altered in Intra-Axial Brain Tumors in Malaysia

( Abdul Aziz Mohamed Yusoff ),( Fatin Najwa Zulfakhar ),( Siti Zulaikha Nashwa Mohd Khair ),( Wan Salihah Wan Abdullah ),( Jafri Malin Abdullah ),( Zamzuri Idris ) 대한뇌종양학회 대한신경종양학회 2018 Brain Tumor Research and Treatment Vol.6 No.1

Background Mitochondria are major cellular sources of reactive oxygen species (ROS) generation which can induce mitochondrial DNA damage and lead to carcinogenesis. The mitochondrial 10398A>G alteration in NADH-dehydrogenase subunit 3 (ND3) can severely impair complex I, a key component of ROS production in the mitochondrial electron transport chain. Alteration in ND3 10398A>G has been reported to be linked with diverse neurodegenerative disorders and cancers. The aim of this study was to find out the association of mitochondrial ND3 10398A>G alteration in brain tumor of Malaysian patients. Methods Brain tumor tissues and corresponding blood specimens were obtained from 45 patients. The ND3 10398A>G alteration at target codon 114 was detected using the PCR-RFLP analysis and later was confirmed by DNA sequencing. Results Twenty-six (57.8%) patients showed ND3 10398A>G mutation in their tumor specimens, in which 26.9% of these mutations were heterozygous mutations. ND3 10398A>G mutation was not significantly correlated with age, gender, and histological tumor grade, however was found more frequently in intra-axial than in extra-axial tumors (62.5% vs. 46.2%, p< 0.01). Conclusion For the first time, we have been able to describe the occurrence of ND3 10398A >G mutations in a Malaysian brain tumor population. It can be concluded that mitochondrial ND3 10398A>G alteration is frequently present in brain tumors among Malaysian population and it shows an impact on the intra-axial tumors.

Expression Profile of Genes Modulated by Aloe emodin in Human U87 Glioblastoma Cells

Haris, Khalilah,Ismail, Samhani,Idris, Zamzuri,Abdullah, Jafri Malin,Yusoff, Abdul Aziz Mohamed Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

Glioblastoma, the most aggressive and malignant form of glioma, appears to be resistant to various chemotherapeutic agents. Hence, approaches have been intensively investigated to targeti specific molecular pathways involved in glioblastoma development and progression. Aloe emodin is believed to modulate the expression of several genes in cancer cells. We aimed to understand the molecular mechanisms underlying the therapeutic effect of Aloe emodin on gene expression profiles in the human U87 glioblastoma cell line utilizing microarray technology. The gene expression analysis revealed that a total of 8,226 gene alterations out of 28,869 genes were detected after treatment with $58.6{\mu}g/ml$ for 24 hours. Out of this total, 34 genes demonstrated statistically significant change (p<0.05) ranging from 1.07 to 1.87 fold. The results revealed that 22 genes were up-regulated and 12 genes were down-regulated in response to Aloe emodin treatment. These genes were then grouped into several clusters based on their biological functions, revealing induction of expression of genes involved in apoptosis (programmed cell death) and tissue remodelling in U87 cells (p<0.01). Several genes with significant changes of the expression level e.g. SHARPIN, BCAP31, FIS1, RAC1 and TGM2 from the apoptotic cluster were confirmed by quantitative real-time PCR (qRT-PCR). These results could serve as guidance for further studies in order to discover molecular targets for the cancer therapy based on Aloe emodin treatment.

Genotype-Phenotype correlation of SMN locus genes in spinal muscular atrophy patients from India

Akanchha Kesari,M Mohammed Idris,Giri Raj Chandak,Balraj Mittal 생화학분자생물학회 2005 Experimental and molecular medicine Vol.37 No.3

Spinal muscular atrophy has been classified into four groups based on the age of onset and clinical severity of the disease. Homozygous deletion in SMN1 gene causes the disease but the clinical severity may be modified by copy number of homologous gene SMN2 as wel as the extent of deletion at SMN locus. In the view of scarcity of genotype and phenotype corela-tion data from India, this study has been under-taken to determine that corelation in SMA pa-SMN and NAIP genes and two polymorphic markers C212 and C272 located in this region. Two to four aleles of the markers C212 and C272 were observed in normal indivi-duals. However, majority of Type I patients show-ed only one alele from both markers whereas in Type II and II patients, 2-3 alleles were observed. The SMN2 copy number in our type II patients showed that patients cary 3-5 copies of SMN2 gene. Our results sugest that extent of deletions encompassing H4F5, SMN1, NAIP and copy num-ber of SMN2 gene can modify the SMA pheno-type, thus acounting for the diferent clinical subtypes of the disease.

Association of The IDH1 C.395G>A (R132H) Mutation with Histological Type in Malay Brain Tumors

Yusoff, Abdul Aziz Mohamed,Zulfakhar, Fatin Najwa,Sul'ain, Mohd Dasuki,Idris, Zamzuri,Abdullah, Jafri Malin Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.12

Background: Brain tumors, constituting one of the most deadly forms of cancer worldwide, result from the accumulation of multiple genetic and epigenetic alterations in genes and signaling pathways. Isocitrate dehydrogenase enzyme isoform 1 (IDH1) mutations are frequently identified in primary brain tumors and acute myeloid leukemia. Studies on IDH1 gene mutations have been extensively performed in various populations worldwide but not in Malaysia. This work was conducted to study the prevalence of IDH1 c.395G>A (R132H) hotspot mutations in a group of Malaysian patients with brain tumors in order to gain local data for the IDH1 mutation profile in our population. Methods: Mutation analysis of c.395G>A (R132H) of IDH1 was performed in 40 brain tumor specimens by the polymerase chain reaction-restriction fragment length polymorphism method (PCR-RFLP) and then verified by direct sequencing. Associations between the IDH1 c.395G>A (R132H) mutation and clinicopathologic characteristics were also analyzed. Results: The IDH1 c.395G>A (R132H) mutation was detected in 14/40 patients (35%). A significant association was found with histological tumor types, but not with age, gender and race. Conclusions: IDH1 is frequently mutated and associated with histological subtypes in Malay brain tumors.

A Hybrid DTC-DSC Drive for High Performance Induction Motor Control

Auzani Jidin,Nik Rumzi Nik Idris,Abdul Halim Mohamed Yatim,Tole Sutikno,Malik E. Elbuluk 전력전자학회 2011 JOURNAL OF POWER ELECTRONICS Vol.11 No.5

This paper describes a hybrid induction motor drive system incorporating DTC-hysteresis and Direct Self Control (DSC) schemes to achieve excellent dynamic performance. The control scheme is switched from a circular to a hexagonal flux locus whenever a dynamic condition is encountered. On the other hand, when the motor operates under steady state conditions, a circular flux locus is used. Without major modifications to the simple structure of a basic DTC, hexagonal flux locus operation is established by modifying the flux error status, before it is fed to the look-up table. The feasibility of the proposed hybrid scheme to achieve excellent control performance is verified by experimental results.

Development of Animal Health Monitoring System based on Wireless Sensor Network

Maliki Danlami,Emmanuel Fiyinfoluwa Ogunbase,Ibrahim Mohammed Abdullahi,Ibrahim Aliyu,Seungmin Oh,Idris Aji Dauda 한국디지털콘텐츠학회 2022 The Journal of Contents Computing Vol.4 No.2

Optimizing the extraction of essential oil from cinnamon leaf (Cinnamomum verum) for use as a potential preservative for minced beef

Yitbarek Reta Merid,Admassu Habtamu,Idris Fekiya Mohammed,Fentie Eskindir Getachew 한국응용생명화학회 2023 Applied Biological Chemistry (Appl Biol Chem) Vol.66 No.-

Cinnamon leaf essential oil extraction using steam distillation method is a time-consuming and energy-intensive process. Furthermore, a lower yield and a higher rate of product degradation are this method’s main drawbacks. Thus, the goal of this research is to optimize the extraction process parameters of cinnamon leaf essential oil in response to maximizing the yield while retaining quality by using response surface methodology (RSM). The application of extracted essential oil on minced beef to assess its preservative effect was also the other objective of this research. Extraction time (120–210 min), extraction temperature (105–115 ℃), and feed mass (300–600 g) were the chosen independent variables of the optimization experiment using central composite design (CCD). Furthermore, the extracted essential oil’s antibacterial and microbiological preservative activity on minced beef was evaluated. At extraction time of 175.43 min, extraction temperature of 105 °C, and a feed mass of 600 g, the optimum predicted value of cinnamon leaf essential oil yield and cinnamaldehyde concentration (% area) was 2.9% and 34.6%, respectively. Moreover, the second-order polynomial equation fits the experimental data for 20-run experimental data. The chemical composition of cinnamon leaf essential oil extracted at optimal conditions was dominated by eugenol (60.68%) and cinnamaldehyde (33.94%). Additionally, the optimally extracted cinnamon essential oil inhibited the growth of bacteria, particularly gram-positive bacteria. After twenty-one days of storage at 4 °C, total viable count of minced beef seasoned with cinnamon essential oil at concentration of 1.2% (v/v) was lower than 106 CFU/g. To conclude, optimized cinnamon leaf essential oil extraction process provides better yield while retaining its functional properties.

Preemptive pregabalin for postoperative analgesia during minimally invasive hysterectomy: a systematic review and meta-analysis of randomized controlled trials

Ahmed Abu-Zaid,Osama Alomar,Nora F AlNaim,Fatimah Shakir Abualsaud,Mohammed Ziad Jamjoom,Latifa F AlNaim,Abdullah AMA Almubarki,Saeed Baradwan,Saud Abdullah Saud Aboudi,Faisal Khalid Idris,Meshael Fod 대한산부인과학회 2022 Obstetrics & Gynecology Science Vol.65 No.2

We aimed to perform a systematic review and meta-analysis of all randomized placebo-controlled trials (RCTs)that examined the analgesic benefits of preemptive pregabalin among patients undergoing minimally invasivehysterectomy. Five major databases were systematically screened from inception until August 29, 2021 Relevantstudies were evaluated for risk of bias. Endpoints were analyzed using the random-effects model and pooled asthe mean difference or risk ratio with a 95% confidence interval. Four studies with seven treatment arms met theinclusion criteria. The total sample size was 304 patients: 193 and 111 patients were allocated to the pregabalin andplacebo groups, respectively. Overall, the included studies revealed a low risk of bias. The summary results revealedthat the mean postoperative pain scores at rest were significantly lower in the pregabalin group than in the controlgroup at 0, 2, 4, 6, 12, and 24 hours. Moreover, the mean postoperative pain scores on movement/coughing weresignificantly lower in the pregabalin group than in the control group at 12 and 24 hours. The rate of patients whowere opioid-free postoperatively was significantly higher in the pregabalin group than in the control group. Therewas no significant difference between the groups in terms of the mean postoperative time to first rescue analgesicand the rates of adverse events. Compared with placebo, preemptive pregabalin was largely safe, and was correlatedwith superior analgesic effects in terms of lower postoperative pain scores and higher opioid-sparing effects. Additional RCTs are needed to confirm these findings.